Journal
AMERICAN JOURNAL OF NEURORADIOLOGY
Volume -, Issue -, Pages -Publisher
AMER SOC NEURORADIOLOGY
DOI: 10.3174/ajnr.A7977
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The study retrospectively reviewed the MR imaging of 27 children to describe the signal of common pediatric orbital lesions on arterial spin-labeling and evaluate its ability to discriminate malignant from benign masses. The arterial spin-labeling perfusion patterns were classified into homogeneous hypoperfusion, heterogeneous hyperperfusion, and homogeneous intense hyperperfusion. Arterial spin-labeling was found to be valuable in improving the diagnostic confidence of some orbital lesions.
Benign and malignant pediatric orbital lesions can sometimes have overlapping features on conventional MR imaging sequences. MR imaging of 27 children was retrospectively reviewed to describe the signal of some common pediatric extraocular orbital lesions on arterial spin-labeling and to evaluate whether this sequence helps to discriminate malignant from benign masses, with or without ADC value measurements. Qualitative and quantitative assessments of arterial spin-labeling CBF and ADC were performed. All lesions were classified into 3 arterial spin-labeling perfusion patterns: homogeneous hypoperfusion (pattern 1, n = 15; benign lesions), heterogeneous hyperperfusion (pattern 2, n = 9; cellulitis, histiocytosis, malignant tumors), and homogeneous intense hyperperfusion (pattern 3, n = 3; infantile hemangiomas). Arterial spin-labeling can be a valuable tool to improve the diagnostic confidence of some orbital lesions, including infantile hemangioma. An algorithm is proposed.
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