Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 69, Pages 13373-13376Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc04759e
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Funding
- 973 Program [2011CB911002]
- NSFC [21475037, 21190044, 21222507, 21175036]
- Foundation for Innovative Research Groups of NSFC [21221003]
- Fundamental Research Funds for the Central Universities
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The interaction between supercharged green fluorescent protein (ScGFP) and graphene oxide (GO) as well as the resulting quenching effect of GO on ScGFP were investigated. Based on this unique quenching effect and the DNA-mediated ScGFP/GO interaction, a label-free fluorescence method has been established for homogeneously assaying the activity and inhibition of base excision repair enzyme.
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