Ring-Opening-Recombination Strategy Based on 2-Methylbenzothiazole Salts: Syntheses of Thiazinopyrrole Fused-Ring Derivatives

This study presents a method for the synthesis of thiazinopyrrole fused ring derivatives utilizing a ring-opening recombination strategy with benzothiazole salts. Thiazolium salts, aldehydes, and amines undergo a cascade cyclization reaction in a one-pot under the solvent conditions of ethanol. +image

Automated summary

This study presents a novel method for synthesizing thiazinopyrrole fused ring derivatives using a ring-opening recombination strategy with benzothiazole salts. Thiazolium salts, aldehydes, and amines undergo a cascade cyclization reaction in ethanol solvent conditions, leading to the efficient synthesis of the desired products.