Nanoparticle-Based Photothermal Therapy for Breast Cancer Noninvasive Treatment

Rapid advancements in materials science and nanotechnology, intertwined with oncology, have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy for cancer. The breast's superficial anatomical location and aesthetic significance render breast cancer a particularly pertinent candidate for the clinical application of PTT following melanoma. This review comprehensively explores the research conducted on the various types of nanoparticles employed in PTT for breast cancer and elaborates on their specific roles and mechanisms of action. The integration of PTT with existing clinical therapies for breast cancer is scrutinized, underscoring its potential for synergistic outcomes. Additionally, the mechanisms underlying PTT and consequential modifications to the tumor microenvironment after treatment are elaborated from a medical perspective. Future research directions are suggested, with an emphasis on the development of integrative platforms that combine multiple therapeutic approaches and the optimization of nanoparticle synthesis for enhanced treatment efficacy. The goal is to push the boundaries of PTT toward a comprehensive, clinically applicable treatment for breast cancer. This paper discusses the photothermal properties and biological mechanisms of nanomaterials, emphasizing a clinical and biological perspective. The primary focus is on current research regarding photothermal nanoparticles for breast cancer treatment: nanoparticle materials, breast characteristics, functional design, and commonly used adjuvant therapy in clinical practice.image

Automated summary

Photothermal therapy (PTT) combined with nanotechnology has emerged as a promising noninvasive treatment strategy for breast cancer. This comprehensive review explores the use of various nanoparticles in PTT for breast cancer, highlighting their specific roles and mechanisms of action. The integration of PTT with existing clinical therapies and the modifications to the tumor microenvironment are also discussed.