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Fangfang Yang et al.
Summary: Sonodynamic therapy (SDT) is a promising modality for anticancer treatments and an interdisciplinary research field. This review provides a comprehensive discussion on ultrasonic cavitation, sonodynamic effect, and sonosensitizers, explaining the basic principles and mechanisms of SDT. The review also highlights the recent progress and advancements of MOF-based sonosensitizers in anticancer applications, and discusses the challenges and potential of MOF-assisted SDT for future advancements. Overall, this review contributes to the development of anticancer nanodrugs and biotechnologies.
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Rui Zhang et al.
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Shuaiqiang Zhang et al.
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Guan-Chi Lee et al.
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Pu Qiu et al.
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Zuoxiu Xiao et al.
Summary: Sonodynamic therapy (SDT) is a promising cancer treatment, but faces challenges in practical application. Metal organic frameworks (MOFs) show great potential in addressing the limitations of SDT.
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Yushan Dong et al.
Summary: In this study, ultrathin 2D Bi2MoO6-poly(ethylene glycol) nanoribbons were designed as piezoelectric sonosensitizers for sonodynamic therapy (SDT), aiming to reduce the scavenging capacity of reactive oxygen species (ROS) and elevate ROS production by consuming endogenous GSH and promoting electron-hole pair separation. The synthesized nanoribbons showed excellent computed tomography imaging of tumors and significant tumor suppression in vitro and in vivo, demonstrating a potential two-step enhancement SDT process activated by endogenous GSH and amplified by exogenous ultrasound.
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Review
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