4.8 Article

Substrate nesting guides cyst morphogenesis of human pluripotent stem cells without 3D extracellular matrix overlay

Related references

Note: Only part of the references are listed.
Review Cell Biology

Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst

Amber E. Carleton et al.

Summary: The formation of a central lumen in the human epiblast is a critical step for development. Recent developments using new model systems have revealed new insights into the molecular and cellular events of this process, including new molecular understanding, a novel pluripotency state, and the mechanisms contributing to lumenogenesis.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2022)

Review Cell Biology

Mechanisms of formation and functions of the early embryonic cavities

Yung Su Kim et al.

Summary: This article discusses the mechanisms of cavity formation in early mouse embryonic development, and describes the formation and functions of the blastocoel and proamniotic cavity.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2022)

Article Developmental Biology

A mechanogenetic role for the actomyosin complex in branching morphogenesis of epithelial organs

Jin Man Kim et al.

Summary: The study reported a mechanogenetic role of the actomyosin complex in branching morphogenesis, revealing the importance of force distribution for promoting the branching process, and the crucial genes regulated by YAP and TAZ for the distribution of epithelial progenitor cells in epithelial organs.

DEVELOPMENT (2021)

Article Physics, Multidisciplinary

Surface-tension-induced budding drives alveologenesis in human mammary gland organoids

Pablo A. Fernandez et al.

Summary: The study found that the morphological transformation of glands is induced by a local change in tension from anisotropic to isotropic within the epithelial cell layer, leading to continuous collective rotation of cells around the branch axis and the eventual formation of spherical tissue buds.

NATURE PHYSICS (2021)

Article Multidisciplinary Sciences

Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids

B. Buchmann et al.

Summary: This study found that the elongation of epithelial ducts within human mammary organoid branches relies on the non-linear and plastic mechanical response of the surrounding collagen. Collective motion of cells generates tension, inducing a plastic reorganization of the collagen network to form mechanically stable collagen cages, which further directs branch outgrowth and matrix deformation.

NATURE COMMUNICATIONS (2021)

Article Chemistry, Multidisciplinary

Viscoelasticity and Adhesion Signaling in Biomaterials Control Human Pluripotent Stem Cell Morphogenesis in 3D Culture

Dhiraj Indana et al.

Summary: This research utilized viscoelastic alginate hydrogels to study hiPSC morphogenesis in 3D culture. Higher RGD density and fast stress relaxation were found to promote hiPSC viability, proliferation, and lumen formation, while slow stress relaxation at low RGD densities triggered hiPSC apoptosis.

ADVANCED MATERIALS (2021)

Article Cell Biology

Cell fate coordinates mechano-osmotic forces in intestinal crypt formation

Qiutan Yang et al.

Summary: This study reveals the simultaneous occurrence of crypt formation and reduction in lumen volume in intestinal organoids derived from single cells. By developing a 3D biophysical model and utilizing multiple mechanical perturbations, it demonstrates the synergistic effects of actomyosin-driven crypt apical contraction and villus basal tension with lumen volume reduction in driving crypt morphogenesis. Additionally, a sodium/glucose cotransporter specific to differentiated enterocytes was identified, which modulates lumen volume reduction through cell swelling in the villus region.

NATURE CELL BIOLOGY (2021)

Article Cell Biology

Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Carlos Perez-Gonzalez et al.

Summary: Intestinal organoids exhibit non-monotonic stress distribution, with distinct mechanical domains affecting cell folding and migration along a gradient of increasing tension.

NATURE CELL BIOLOGY (2021)

Article Cell & Tissue Engineering

ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

Robin Lovell-Badge et al.

Summary: The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation to address advances in the field and the associated ethical, social, and policy issues. The basic principles remain unchanged while serving as a standard resource for scientists, regulators, and the public.

STEM CELL REPORTS (2021)

Article Engineering, Biomedical

Microengineered human amniotic ectoderm tissue array for high-content developmental phenotyping

Sajedeh Nasr Esfahani et al.

BIOMATERIALS (2019)

Review Cell Biology

Opening the black box: Stem cell-based modeling of human post-implantation development

Kenichiro Taniguchi et al.

JOURNAL OF CELL BIOLOGY (2019)

Article Nanoscience & Nanotechnology

Biochemical Ligand Density Regulates Yes-Associated Protein Translocation in Stem Cells through Cytoskeletal Tension and Integrins

Alice E. Stanton et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Cell Biology

An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells

Kenichiro Taniguchi et al.

JOURNAL OF CELL BIOLOGY (2017)

Article Multidisciplinary Sciences

A pluripotent stem cell-based model for post-implantation human amniotic sac development

Yue Shao et al.

NATURE COMMUNICATIONS (2017)

Review Developmental Biology

Tension, contraction and tissue morphogenesis

Natalie C. Heer et al.

DEVELOPMENT (2017)

Editorial Material Multidisciplinary Sciences

Revisit the 14-day rule

Insoo Hyun et al.

NATURE (2016)

Article Multidisciplinary Sciences

Self-organization of the in vitro attached human embryo

Alessia Deglincerti et al.

NATURE (2016)

Article Cell Biology

Self-organization of the human embryo in the absence of maternal tissues

Marta N. Shahbazi et al.

NATURE CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

How actin/myosin crosstalks guide the adhesion, locomotion and polarization of cells

Erich Sackmann

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)

Review Cell & Tissue Engineering

Mechanism of regulation of stem cell differentiation by matrix stiffness

Hongwei Lv et al.

STEM CELL RESEARCH & THERAPY (2015)

Article Cell & Tissue Engineering

Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells

Kenichiro Taniguchi et al.

STEM CELL REPORTS (2015)

Article Biophysics

Spherical indentation method for determining the constitutive parameters of hyperelastic soft materials

Man-Gong Zhang et al.

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2014)

Review Cell Biology

Mechanotransduction and extracellular matrix homeostasis

Jay D. Humphrey et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

Theory of epithelial sheet morphology in three dimensions

Edouard Hannezo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Effect of Substrate Stiffness on Early Mouse Embryo Development

Kevin S. Kolahi et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Forces Driving Epithelial Spreading in Zebrafish Gastrulation

Martin Behrndt et al.

SCIENCE (2012)

Review Cell Biology

Biomechanical regulation of contractility: spatial control and dynamics

Romain Levayer et al.

TRENDS IN CELL BIOLOGY (2012)

Article Biochemical Research Methods

Increased poly(dimethylsiloxane) stiffness improves viability and morphology of mouse fibroblast cells

Joong Yull Park et al.

BIOCHIP JOURNAL (2010)

Article Multidisciplinary Sciences

Pulsed contractions of an actin-myosin network drive apical constriction

Adam C. Martin et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity

Wei Yu et al.

EMBO REPORTS (2008)

Article Cell Biology

Myosin II regulates the shape of three-dimensional intestinal epithelial cysts

Andrei I. Ivanov et al.

JOURNAL OF CELL SCIENCE (2008)

Article Multidisciplinary Sciences

Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration

Seema Grewal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Cell Biology

Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis

Thomas Lecuit et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)