4.8 Article

Chemodynamic/Photothermal Synergistic Cancer Immunotherapy Based on Yeast Microcapsule-Derived Au/Pt Nanoparticles

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth

Jialu Xu et al.

Summary: This article discusses the research progress of microbe-based cancer immunotherapy, inducing anticancer immunity through the preparation of nanoparticles of different sizes. The study found that the size of the formulations inversely correlates with their accumulation ability in tumor-draining lymph nodes, showing potential therapeutic effects.

NATURE COMMUNICATIONS (2022)

Article Biotechnology & Applied Microbiology

All-in-one approaches for triple-negative breast cancer therapy: metal-phenolic nanoplatform for MR imaging-guided combinational therapy

Qi Xie et al.

Summary: A nano-system was developed to integrate imaging and combinational therapy for triple-negative breast cancer (TNBC). The system encapsulates drugs and photothermal transduction agents, and serves as an MRI contrast agent, achieving integrated diagnosis and treatment.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

Article Nanoscience & Nanotechnology

Yeast Microcapsule Mediated Natural Products Delivery for Treating Ulcerative Colitis through Anti-Inflammatory and Regulation of Macrophage Polarization

Xingxing Feng et al.

Summary: This study designed a macrophages-targeting oral drug delivery system for ulcerative colitis, using berberine and Epigallocatechin Gallate encapsulated in yeast microcapsules. The system effectively transported the drugs to inflammation sites and exerted anti-inflammatory effects through the interaction with macrophage receptors. It provided a new targeting strategy for UC treatment.

ACS APPLIED MATERIALS & INTERFACES (2022)

Review Oncology

Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors

Liangliang Xu et al.

Summary: The development of combination immunotherapy based on regulatory mechanisms of the tumor immune microenvironment (TIME) is promising. This review focuses on recent advances in single-cell transcriptomics and spatial transcriptomics for the study of the systemic tumor immune environment (STIE), TIME, and their interactions. The understanding of heterogeneity and dynamic changes in response to immunotherapy may enhance treatment efficacy.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2022)

Article Chemistry, Multidisciplinary

Precise Chemodynamic Therapy of Cancer by Trifunctional Bacterium-Based Nanozymes

Weiyun Zhang et al.

Summary: The study introduces a novel chemodynamic therapy (CDT) nanodrug, utilizing a bacterial surface decorated Au@Pt nanozyme (Bac-Au@Pt) for precise treatment of tumors. By releasing ROS to tumor cells and reducing the intracellular reductants in a tumor-specific manner, the nanosystem achieves effective therapeutic efficacy at a very low dose for tumor cells with no toxic side effects on normal cells.

ACS NANO (2021)

Article Pharmacology & Pharmacy

Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Yu Liang et al.

Summary: Novel tumor microenvironment-activated metal-organic frameworks involving Fe & Cu ions were developed for targeted ferroptosis therapy, releasing Fe ions and inhibiting GPX4 to induce cell death. These frameworks can generate more ROS under specific TME conditions, showing promising anti-tumor efficacy.

ACTA PHARMACEUTICA SINICA B (2021)

Review Biochemistry & Molecular Biology

Intratumoral heterogeneity in cancer progression and response to immunotherapy

Ilio Vitale et al.

Summary: Tumors evolve under various pressures and exhibit considerable heterogeneity in genetic, phenotypic, and behavioral aspects. This intratumoral heterogeneity influences disease progression and treatment sensitivity, necessitating consideration of multiple levels of heterogeneity in future therapeutic approaches.

NATURE MEDICINE (2021)

Article Chemistry, Multidisciplinary

Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy

Xue-Liang Liu et al.

Summary: Nano-Pt loaded liposomal system enhances photodynamic therapy and chemotherapy in cancer treatment by increasing oxygen supply and releasing nanoparticles for better penetration, leading to inhibited tumor growth and extended survival without toxicity in animal models.

ADVANCED SCIENCE (2021)

Article Chemistry, Multidisciplinary

Engineering a sustained release vaccine with a pathogen-mimicking manner for robust and durable immune responses

Yingying Hou et al.

Summary: A sustained antigen delivery vector carrying abundant antigens, a nucleic acid adjuvant and pathogen-associated molecular patterns is reported to strengthen immune responses by mimicking a natural pathogen. This approach achieves stronger antibody responses, Th1 and Th17 biased cellular immunity, immune memory, and significantly suppresses tumor growth in a therapeutic tumor model. This work sheds light on the efficacy of combining sustained antigen release with pathogen-mimicking manner in vaccine design.

JOURNAL OF CONTROLLED RELEASE (2021)

Review Oncology

Next frontier in tumor immunotherapy: macrophage-mediated immune evasion

Yingqi Qiu et al.

Summary: This review highlights the critical role of TAMs in tumor immune evasion, discussing their interactions with other immune cells and factors, and summarizing relevant studies to provide new insights for immunotherapy. Macrophage-targeted therapy is expected to be the next frontier in cancer immunotherapy.

BIOMARKER RESEARCH (2021)

Review Nanoscience & Nanotechnology

Rational design of nanomedicine for photothermal-chemodynamic bimodal cancer therapy

Junlie Yao et al.

Summary: Traditional nanomedicine faces challenges in treating persistent tumors, but recent advancements in photothermal-chemodynamic bimodal therapy (PTT/CDT) nanomedicine have shown promising results in efficient and safe cancer treatment. Integrating different functional units into one nanomedicine is a meaningful task that can lead to significant synergistic effects.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2021)

Article Medicine, Research & Experimental

Silicon nanowires decorated with platinum nanoparticles were applied for photothermal-enhanced sonodynamic therapy

Lina Sun et al.

Summary: The developed Si-Pt NCs exhibit strong sonodynamic therapy and chemodynamic therapy effects, with a higher therapeutic efficacy. Taking advantage of the mesoporous structure, the mild photothermal effect further enhances the combined cancer therapy of SDT and CDT provided by Si-Pt NCs.

THERANOSTICS (2021)

Review Immunology

Top 10 Challenges in Cancer Immunotherapy

Priti S. Hegde et al.

IMMUNITY (2020)

Article Multidisciplinary Sciences

Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

Daniel S. Leventhal et al.

NATURE COMMUNICATIONS (2020)

Article Chemistry, Physical

Mesoporous platinum nanoparticle-based nanoplatforms for combined chemo-photothermal breast cancer therapy

Bei Fu et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2020)

Article Cell Biology

Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors

Anthony K. Park et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

Review Chemistry, Multidisciplinary

Recent progress of chemodynamic therapy-induced combination cancer therapy

Xianwen Wang et al.

NANO TODAY (2020)

Review Immunology

Enhancing cancer immunotherapy with nanomedicine

Darrell J. Irvine et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Immunology

Dendritic cells in cancer immunology and immunotherapy

Stefanie K. Wculek et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Chemistry, Multidisciplinary

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions

Zhongmin Tang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Biotechnology & Applied Microbiology

Programmed ROS/CO-releasing nanomedicine for synergetic chemodynamic-gas therapy of cancer

Bin Zhao et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Review Engineering, Biomedical

Nanocatalysts-augmented Fenton chemical reaction for nanocatalytic tumor therapy

Xiaoqin Qian et al.

BIOMATERIALS (2019)

Review Biotechnology & Applied Microbiology

Yeast-based vaccines: New perspective in vaccine development and application

Ravinder Kumar et al.

FEMS YEAST RESEARCH (2019)

Review Biochemistry & Molecular Biology

Understanding the tumor immune microenvironment (TIME) for effective therapy

Mikhail Binnewies et al.

NATURE MEDICINE (2018)

Review Urology & Nephrology

Potentiating prostate cancer immunotherapy with oncolytic viruses

Patrick Lee et al.

NATURE REVIEWS UROLOGY (2018)

Review Biochemistry & Molecular Biology

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

Miguel F. Sanmamed et al.

Review Biotechnology & Applied Microbiology

Gold nanoparticle-mediated photothermal therapy: current status and future perspective

Sekyu Hwang et al.

NANOMEDICINE (2014)

Review Nanoscience & Nanotechnology

Biosynthesis of Metal Nanoparticles: A Review

Narendra Kulkarni et al.

JOURNAL OF NANOTECHNOLOGY (2014)

Review Biotechnology & Applied Microbiology

Mechanistic aspects in the biogenic synthesis of extracellular metal nanoparticles by peptides, bacteria, fungi, and plants

Nelson Duran et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)

Review Nanoscience & Nanotechnology

Biosynthesis of Nanoparticles by Microorganisms and Their Applications

Xiangqian Li et al.

JOURNAL OF NANOMATERIALS (2011)