Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 43, Pages 9038-9041Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc02052b
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Funding
- Global Innovative Research Center (GiRC) program through the National Research Foundation (NRF) - Ministry of Education, Science and Technology [NRF-2012K1A1A2A01056094]
- National R&D Program for Cancer Control, Ministry for Health and Welfare, Republic of Korea [1220050]
- Korea Health Promotion Institute [1220050] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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In this study, multivalent carrier-free aptamer-RNA based fluorescent probes (CF-probes) were designed as a simpler, more reliable, timesaving strategy for cellular miRNA detection. CF-probes spontaneously delivered into cells without the need for additional carriers and visualized target microRNA-34a specifically.
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