4.8 Article

Artificial Periosteum with Oriented Surface Nanotopography and High Tissue Adherent Property

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

Three-dimensional bioprinted BMSCs-laden highly adhesive artificial periosteum containing gelatin-dopamine and graphene oxide nanosheets promoting bone defect repair

Xin Sun et al.

Summary: In this study, a modified gelatin-dopamine composite bioink was developed by grafting dopamine onto the molecular chain of gelatin, and it was used for constructing an artificial periosteum through 3D bioprinting. The results showed that the developed bioink exhibited good thermosensitivity and printability, and could be used to fabricate a 3D bioprinted artificial periosteum with high cell viability and adhesion. Additionally, the 3D bioprinted artificial periosteum effectively promoted osteogenesis both in vitro and in vivo. Therefore, the developed 3D bioprinted artificial periosteum holds great promise for bone defect repair.

BIOFABRICATION (2023)

Review Nanoscience & Nanotechnology

Vertically Aligned Carbon Nanotubes as a Unique Material for Biomedical Applications

August Kohls et al.

Summary: Vertically aligned carbon nanotubes (VACNTs) have numerous advantages that make them highly desirable in biomedical applications. This review discusses the utilization of VACNTs in sensing, biomolecule filtration systems, cell stimulation, regenerative medicine, drug delivery, and bacteria inhibition, and compares them to the traditionally nonaligned, randomly oriented nanotubes.

ACS APPLIED MATERIALS & INTERFACES (2022)

Article Nanoscience & Nanotechnology

Biomass Microcapsules with Stem Cell Encapsulation for Bone Repair

Lei Yang et al.

Summary: Stem cell transplantation has emerged as an alternative approach for bone repair due to its excellent biological activities and therapy effect. This study developed a novel core-shell microcapsule with a stem cell-laden core and a biomass shell, which showed good biocompatibility and therapeutic effect for bone defects.

NANO-MICRO LETTERS (2022)

Article Engineering, Biomedical

A tannic acid doped hydrogel with small extracellular vesicles derived from mesenchymal stem cells promotes spinal cord repair by regulating reactive oxygen species microenvironment

Zhong Liu et al.

Summary: This study found that sEVs have potential therapeutic effects in the treatment of spinal cord injury. By fabricating a novel sEVs-releasing hydrogel, the researchers successfully promoted the recovery of motor function after spinal cord injury and effectively regulated the inflammatory and ROS microenvironment.

MATERIALS TODAY BIO (2022)

Article Nanoscience & Nanotechnology

3D Polycaprolactone/Gelatin-Oriented Electrospun Scaffolds Promote Periodontal Regeneration

Xuanwen Xu et al.

Summary: Periodontitis is a chronic inflammatory disease that affects people worldwide and has an uncertain prognosis with surgical treatment. In this study, a three-dimensional scaffold made of electrospun polycaprolactone/gelatin fibrous membranes was developed to overcome the challenges of periodontal treatment. The scaffold showed good properties and promoted adhesion and proliferation of human periodontal ligament stem cells. In vivo experiments confirmed that the scaffold could guide cellular orientation and potentially facilitate periodontal regeneration.

ACS APPLIED MATERIALS & INTERFACES (2022)

Article Nanoscience & Nanotechnology

Rotary Jet-Spun Polycaprolactone/Hydroxyapatite and Carbon Nanotube Scaffolds Seeded with Bone Marrow Mesenchymal Stem Cells Increase Bone Neoformation

Mirian M. Machado-Paula et al.

Summary: In this study, a next-generation bone regeneration material was developed by combining polycaprolactone fibers, carbon nanotubes, and hydroxyapatite nanoparticles. Rotary jet spinning fibers showed the best outcomes in repairing rat calvarial defects, and their rough topography allowed for better cellular growth and spreading. Incorporating nanoparticles and bone marrow mesenchymal stem cells enhanced cell performance and resulted in greater bone neoformation.

ACS APPLIED BIO MATERIALS (2022)

Article Cell & Tissue Engineering

Construction of developmentally inspired periosteum-like tissue for bone regeneration

Kai Dai et al.

Summary: The periosteum, a highly vascularized thin tissue, has excellent osteogenic and bone regenerative abilities. Creating periosteum-like tissue using a BMP-2-loaded scaffold in vivo can be an effective strategy for bone defect repair and regeneration. The study found that BMP-2-induced endochondral ossification plays a crucial role in the construction of periosteum-like tissue.

BONE RESEARCH (2022)

Article Chemistry, Multidisciplinary

Ice-Inspired Lubricated Drug Delivery Particles from Microfluidic Electrospray for Osteoarthritis Treatment

Lei Yang et al.

Summary: Particle-based drug delivery systems show significant value in osteoarthritis treatment. By developing functional particles with enhanced lubrication and therapeutic effects through microfluidic electrospray, potential applications in clinical settings are promising. This approach offers precise control over particle size, chemical modification, and drug loading, showcasing great potential for improved treatment outcomes.

ACS NANO (2021)

Article Engineering, Biomedical

Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration

Gaojie Yang et al.

Summary: The functional biomimetic membrane with micropatterns of site-specific biomineralization mimics the role of natural periosteum in bone regeneration. It can sustainably release calcium phosphate and growth factors, enhancing cell recruitment and differentiation, leading to improved vascularized ossification and accelerated new bone formation in a rat model.

BIOMATERIALS (2021)

Article Engineering, Biomedical

Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature

Yiming Li et al.

Summary: Decellularized allografts, commonly used for critical size bone defects, have high long-term failure rates due to lack of periosteum. Recent studies show that MMP-TEP modified allografts can effectively coordinate host neurovasculature, leading to improved bone healing outcomes.

BIOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Biomimetic, Stiff, and Adhesive Periosteum with Osteogenic-Angiogenic Coupling Effect for Bone Regeneration

Yuhe Yang et al.

Summary: The study presents the development of a periosteum mimicking bone aid (PMBA) with enhanced mechanical strength, tissue adhesiveness, and sustained activation of nitric oxide-cyclic guanosine monophosphate (NO-cGMP) signaling pathway for accelerated bone regeneration. This concept involves considering both the initial material components and the degradation products in promoting physiological activities, aiming to inspire the design of high-performance bioscaffolds for bone and periosteum tissue engineering.

SMALL (2021)

Article Biochemistry & Molecular Biology

Periosteum-Mimicking Tissue-Engineered Composite for Treating Periosteum Damage in Critical-Sized Bone Defects

Sneha Gupta et al.

Summary: The study developed a biomimetic periosteum membrane and a bioactive inorganic-organic composite cryogel for promoting periosteal regeneration and bone formation in in vitro oxidative stress model and rat tibial bone fracture model.

BIOMACROMOLECULES (2021)

Article Engineering, Biomedical

Hierarchical Nanostructured Electrospun Membrane with Periosteum-Mimic Microenvironment for Enhanced Bone Regeneration

Laijun Liu et al.

Summary: The developed hierarchical nanostructured electrospun membrane with periosteum-mimic microenvironment, incorporating a calcium-binding peptide, showed enhanced osteogenic differentiation of rat-bone marrow-derived mesenchymal stem cells (rBMSCs) and promoted the regeneration of vascularized bone tissue.

ADVANCED HEALTHCARE MATERIALS (2021)

Article Materials Science, Biomaterials

Carbon nanotube-reinforced cell-derived matrix-silk fibroin hierarchical scaffolds for bone tissue engineering applications

Rafael Lemos et al.

Summary: The study developed advanced hierarchical scaffolds composed of silk fibroin, cell-derived extracellular matrix, and carbon nanotubes to improve the performance of standard silk fibroin scaffolds. The scaffolds were fabricated using various methods and showed satisfactory pore structure and mechanical properties for bone regeneration applications. In vitro studies demonstrated the bioactivity of the scaffolds and their support for cell proliferation, indicating their potential for bone tissue engineering.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Article Chemistry, Multidisciplinary

Graphene Hybrid Anisotropic Structural Color Film for Cardiomyocytes' Monitoring

Linjie Li et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Article Multidisciplinary Sciences

Bioinspired structural color patch with anisotropic surface adhesion

Yu Wang et al.

SCIENCE ADVANCES (2020)

Article Chemistry, Multidisciplinary

Cardiomyocyte-Driven Structural Color Actuation in Anisotropic Inverse Opals

Yixuan Shang et al.

ACS NANO (2019)

Review Cell Biology

Animal models for bone tissue engineering and modelling disease

Jacqui Anne McGovern et al.

DISEASE MODELS & MECHANISMS (2018)

Article Engineering, Biomedical

Aligned nanofiber material supports cell growth and increases osteogenesis in canine adipose-derived mesenchymal stem cells in vitro

Sony Pandey et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2018)

Review Dentistry, Oral Surgery & Medicine

A Review of the Impact of Implant Biomaterials on Osteocytes

F. A. Shah et al.

JOURNAL OF DENTAL RESEARCH (2018)

Article Nanoscience & Nanotechnology

Inorganic Strengthened Hydrogel Membrane as Regenerative Periosteum

Tianwen Xin et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Article Engineering, Biomedical

Multiscale patterned transplantable stem cell patches for bone tissue regeneration

Jangho Kim et al.

BIOMATERIALS (2014)

Review Cell Biology

Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation

Yang-Kao Wang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2013)

Review Nanoscience & Nanotechnology

Carbon nanotubes: Their potential and pitfalls for bone tissue regeneration and engineering

Peter Newman et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2013)

Article Chemistry, Physical

The conflicts between strength and toughness

Robert O. Ritchie

NATURE MATERIALS (2011)

Article Engineering, Biomedical

In vitro calcification of chemically functionalized carbon nanotubes

Johanne Beuvelot et al.

ACTA BIOMATERIALIA (2010)