4.1 Editorial Material

Dietary microRNAs: Could They Be Considered Nutraceuticals?

Related references

Note: Only part of the references are listed.
Article Agriculture, Multidisciplinary

Digestion of Plant Dietary miRNAs Starts in the Mouth under the Protection of Coingested Food Components and Plant-Derived Exosome-like Nanoparticles

Xinshu Qin et al.

Summary: This study reveals the potential of plant miRNAs in cross-kingdom effects by investigating their stability in human saliva.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022)

Article Cell Biology

SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

Qun Chen et al.

Summary: The study reveals that SIDT1 expressed on gastric pit cells is necessary for the absorption of dietary microRNAs, and deficiency in SIDT1 leads to reduced absorption. The stomach is identified as the primary site for dietary microRNA absorption, and the process relies on SIDT1 and low pH. Oral administration of plant-derived miR2911 can delay liver fibrosis, but this effect is nullified in SIDT1-deficient mice.

CELL RESEARCH (2021)

Review Agriculture, Multidisciplinary

Insights into Health-Promoting Effects of Plant MicroRNAs: A Review

Wen-Jing Zhu et al.

Summary: Plant-derived miRNAs play a significant role in human health by affecting food quality, protein expression in host cells, and reshaping the human gut microbiota. They contribute to the cross-kingdom communication and balance among plants, gut microbiota, and hosts.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Agriculture, Multidisciplinary

Connection between miRNA Mediation and the Bioactive Effects of Broccoli (Brassica oleracea var. italica): Exogenous miRNA Resistance to Food Processing and GI Digestion

Luis A. Chapado et al.

Summary: The study suggests that bioactive compounds in broccoli may exert beneficial health effects through miRNA regulation, and the anticarcinogenic properties of cruciferous vegetables may be mediated by miRNA-related mechanisms. Furthermore, miRNAs derived from broccoli can survive common food-processing conditions and GI digestion.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Microbiology

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

Yun Teng et al.

CELL HOST & MICROBE (2018)