3.8 Review

Progesterone receptor ligands for the treatment of endometriosis

Related references

Note: Only part of the references are listed.
Editorial Material Obstetrics & Gynecology

Evaluation of marketing authorization and clinical implementation of ulipristal acetate for uterine fibroids

Mei-An Middelkoop et al.

Summary: This paper reviews the marketing authorization and implementation process of UPA, highlighting its limitations in terms of study population representativeness, lack of surgical outcome evaluation, and absence of comparative groups for intermittent treatment. The paper emphasizes the need for regulatory measures to ensure the generation of necessary evidence before widespread prescription of new drugs.

HUMAN REPRODUCTION (2022)

Article Endocrinology & Metabolism

Long-term treatment of endometriosis-related pain among women seeking hormonal contraception

Silvia Vannuccini et al.

Summary: This study evaluated the effects of desogestrel (DSG) and combined oral contraceptives (COCs) on treating endometriosis-related pain. The results showed that both treatments were effective in reducing pain, but patients treated with DSG experienced lower levels of dysmenorrhea, dyspareunia, and nonmenstrual pelvic pain.

GYNECOLOGICAL ENDOCRINOLOGY (2022)

Article Endocrinology & Metabolism

Hormonal treatments for endometriosis: The endocrine background

Silvia Vannuccini et al.

Summary: Endometriosis is a chronic uterine disorder that affects women's health, and hormonal drugs are the main medical treatment used to manage the disease based on endocrine and inflammatory changes. The key events causing pain and infertility are estrogen-dependency and progesterone-resistance. Current treatments aim to inhibit menstruation, block the hypothalamus-pituitary-ovary axis, and control the progression of endometriotic implants.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2022)

Article Medicine, General & Internal

A new validated screening method for endometriosis diagnosis based on patient questionnaires

Charles Chapron et al.

Summary: This study developed scoring systems based on patient questionnaires to identify a high-risk population for endometriosis diagnosis, improving sensitivity and specificity.

ECLINICALMEDICINE (2022)

Review Family Studies

Norethisterone and its acetate - what's so special about them?

Emilia Huvinen et al.

Summary: Progestogens like norethisterone (NET) are commonly used for contraception, hormone therapy, and treatment of various gynecological conditions. NET can partially convert to ethinylestradiol (EE), with positive effects on the endometrium, bone density, and cardiovascular health. However, long-term use of NET may slightly increase the risk of breast cancer and venous thromboembolism, especially in women with migraine with aura.

BMJ SEXUAL & REPRODUCTIVE HEALTH (2021)

Article Obstetrics & Gynecology

Dydrogesterone in the treatment of endometriosis: evidence mapping and meta-analysis

Chao Peng et al.

Summary: 19 studies involving 1709 female participants were included in the data synthesis. Dydrogesterone was found to relieve dysmenorrhea, increase pregnancy rate, and reduce certain adverse events compared to gestrinone. It also lowered the risk of endometriosis recurrence and elevated transaminase levels compared to GnRH agonists. Efficacy differences between dydrogesterone and leuprolide acetate, letrozole, or traditional Chinese medicine remain unclear due to insufficient data.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2021)

Review Biochemistry & Molecular Biology

Endometriosis: Etiology, pathobiology, and therapeutic prospects

Philippa T. K. Saunders et al.

Summary: Endometriosis is a common condition associated with infertility that causes chronic pain in women. The exact cause and natural history are still uncertain, but hormonal, neurological, and immunological factors are believed to play a role in the development of symptoms. Current interventions have limited efficacy with high rates of symptom recurrence.
Article Obstetrics & Gynecology

Ulipristal Acetate Prior to Surgery for Endometriosis

Sukhbir S. Singh et al.

REPRODUCTIVE SCIENCES (2020)

Review Obstetrics & Gynecology

Clinical management of endometriosis

Miguel A. Luna Russo et al.

MINERVA GINECOLOGICA (2020)

Article Obstetrics & Gynecology

Progesterone Receptor B (PGR-B) Is Partially Methylated in Eutopic Endometrium From Infertile Women With Endometriosis

Carlos Valerio Rocha-Junior et al.

REPRODUCTIVE SCIENCES (2019)

Review Endocrinology & Metabolism

Endometriosis

Serdar E. Bulun et al.

ENDOCRINE REVIEWS (2019)

Article Obstetrics & Gynecology

Dienogest or Norethindrone acetate for the treatment of ovarian endometriomas: Can we avoid surgery?

Simona Del Forno et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2019)

Review Endocrinology & Metabolism

Rethinking mechanisms, diagnosis and management of endometriosis

Charles Chapron et al.

NATURE REVIEWS ENDOCRINOLOGY (2019)

Article Obstetrics & Gynecology

Clinical diagnosis of endometriosis: a call to action

Sanjay K. Agarwal et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2019)

Article Obstetrics & Gynecology

From pathogenesis to clinical practice: Emerging medical treatments for endometriosis

Sara Clemenza et al.

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2018)

Article Obstetrics & Gynecology

Dienogest therapy during the early stages of recurrence of endometrioma might be an alternative therapeutic option to avoid repeat surgeries

Akemi Koshiba et al.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2018)

Article Obstetrics & Gynecology

Comparison of the efficacy of diegnogest and levonorgestrel-releasing intrauterine system after laparoscopic surgery for endometriosis

Ki H. Lee et al.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2018)

Review Endocrinology & Metabolism

Progesterone Resistance in Endometriosis: an Acquired Property?

Brett McKinnon et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2018)

Article Obstetrics & Gynecology

Long-term treatment of endometriosis with dienogest: retrospective analysis of efficacy and safety in clinical practice

Thomas Roemer

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2018)

Article Obstetrics & Gynecology

Dienogest Versus Leuprolide Acetate for Recurrent Pelvic Pain Following Laparoscopic Treatment of Endometriosis

Ahmed Mahmoud Abdou et al.

JOURNAL OF OBSTETRICS AND GYNECOLOGY OF INDIA (2018)

Article Obstetrics & Gynecology

Effect of dienogest on pain and ovarian endometrioma occurrence after laparoscopic resection of uterosacral ligaments with deep infiltrating endometriosis

Akiyoshi Yamanaka et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2017)

Article Obstetrics & Gynecology

Dienogest and deep infiltrating endometriosis: The remission of symptoms is not related to endometriosis nodule remission

Joao Paulo Leonardo-Pinto et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2017)

Article Obstetrics & Gynecology

Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis

Matteo Morotti et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2017)

Review Pharmacology & Pharmacy

Oral and depot progestin therapy for endometriosis: towards a personalized medicine

Laura Buggio et al.

EXPERT OPINION ON PHARMACOTHERAPY (2017)

Article Obstetrics & Gynecology

Postoperative maintenance levonorgestrel-releasing intrauterine system and endometrioma recurrence: a randomized controlled study

Yi-Jen Chen et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2017)

Review Obstetrics & Gynecology

Progesterone resistance in endometriosis: origins, consequences and interventions

Bansari G. Patel et al.

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA (2017)

Article Obstetrics & Gynecology

Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study

Paolo Vercellini et al.

FERTILITY AND STERILITY (2016)

Review Pharmacology & Pharmacy

Innovations in classical hormonal targets for endometriosis

Nicola Pluchino et al.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2016)

Article Obstetrics & Gynecology

Long-term administration of dienogest reduces recurrence after excision of endometrioma

Yoshiaki Ota et al.

JOURNAL OF ENDOMETRIOSIS AND PELVIC PAIN DISORDERS (2015)

Article Obstetrics & Gynecology

Progestin-only contraception compared with extended combined oral contraceptive in women with migraine without aura: a retrospective pilot study

Matteo Morotti et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2014)

Article Obstetrics & Gynecology

Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment

Matteo Morotti et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2014)

Review Pharmacology & Pharmacy

Dienogest in the treatment of endometriosis

Nicolo Bizzarri et al.

EXPERT OPINION ON PHARMACOTHERAPY (2014)

Article Obstetrics & Gynecology

Treatment of pelvic pain associated with endometriosis: a committee opinion

Samantha Pfeifer et al.

FERTILITY AND STERILITY (2014)

Article Obstetrics & Gynecology

Interest of selective progesterone receptor modulators in endometriosis

P. Merviel et al.

GYNECOLOGIE OBSTETRIQUE & FERTILITE (2013)

Article Obstetrics & Gynecology

Consensus on current management of endometriosis

Neil P. Johnson et al.

HUMAN REPRODUCTION (2013)

Review Obstetrics & Gynecology

The social and psychological impact of endometriosis on womens lives: a critical narrative review

Lorraine Culley et al.

HUMAN REPRODUCTION UPDATE (2013)

Article Endocrinology & Metabolism

Increased AKT or MEK1/2 Activity Influences Progesterone Receptor Levels and Localization in Endometriosis

Jennifer L. Eaton et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Medicine, Research & Experimental

Analysis of the levonorgestrel-releasing intrauterine system in women with endometriosis

Shen Lan et al.

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2013)

Article Obstetrics & Gynecology

Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment

Felice Petraglia et al.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2012)

Review Cell Biology

The immninent dawn of SPRMs in obstetrics and gynecology

Nathalie Chabbert-Buffet et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)

Article Reproductive Biology

Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis

Atsushi Hayashi et al.

JOURNAL OF OVARIAN RESEARCH (2012)

Review Medicine, General & Internal

Progestagens and anti-progestagens for pain associated with endometriosis

Julie Brown et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)

Article Obstetrics & Gynecology

Selective progesterone receptor modulators in reproductive medicine: pharmacology, clinical efficacy and safety

Philippe Bouchard et al.

FERTILITY AND STERILITY (2011)

Article Biochemistry & Molecular Biology

Selectivity and potency of the retroprogesterone dydrogesterone in vitro

Tea Lanisnik Rizner et al.

STEROIDS (2011)

Article Obstetrics & Gynecology

Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study

Thomas Strowitzki et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2010)

Article Pharmacology & Pharmacy

A novel mifepristone-loaded implant for long-term treatment of endometriosis: In vitro and in vivo studies

Lin Mei et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Obstetrics & Gynecology

A dose-ranging study to determine the efficacy and safety of 1, 2, and 4 mg of dienogest daily for endometriosis

Guenter Koehler et al.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2010)

Article Obstetrics & Gynecology

Practice Bulletin No. 114: Management of Endometriosis

OBSTETRICS AND GYNECOLOGY (2010)

Article Endocrinology & Metabolism

The Progesterone Receptor Coactivator Hic-5 Is Involved in the Pathophysiology of Endometriosis

Lusine Aghajanova et al.

ENDOCRINOLOGY (2009)

Article Obstetrics & Gynecology

Long-term use of dienogest for the treatment of endometriosis

Mikio Momoeda et al.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2009)

Review Obstetrics & Gynecology

Depot-medroxyprogesterone acetate: an update

Sayed Bakry et al.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2008)

Article Obstetrics & Gynecology

Use of a progestogen only preparation containing desogestrel in the treatment of recurrent pelvic pain after conservative surgery for endometriosis

Sandro Razzi et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2007)

Article Endocrinology & Metabolism

Formation of ethinyl estradiol in women during treatment with norethindrone acetate

Micheline C. Chu et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Article Biochemistry & Molecular Biology

Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis

Yan Wu et al.

EPIGENETICS (2006)

Article Obstetrics & Gynecology

Reduction of apoptosis and proliferation in endometriosis

A Béliard et al.

FERTILITY AND STERILITY (2004)

Review Medicine, General & Internal

Endometriosis

LC Giudice et al.

LANCET (2004)

Article Endocrinology & Metabolism

Progesterone receptor isoform A but not B is expressed in endometriosis

GR Attia et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2000)