Journal
MEASUREMENT SCIENCE AND TECHNOLOGY
Volume 28, Issue 1, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/1361-6501/28/1/012003
Keywords
time-correlated single photon counting; fluorescence lifetime imaging; microchannel plate; single-photon avalanche diode array; single photon detection
Funding
- UK's Medical Research Council (MRC)
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Time-correlated single photon counting (TCSPC) is a widely used, robust and mature technique to measure the photon arrival time in applications such as fluorescence spectroscopy and microscopy, LIDAR and optical tomography. In the past few years there have been significant developments with wide-field TCSPC detectors, which can record the position as well as the arrival time of the photon simultaneously. In this review, we summarise different approaches used in wide-field TCSPC detection, and discuss their merits for different applications, with emphasis on fluorescence lifetime imaging.
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