Glymphatic system and post-hemorrhagic hydrocephalus

Review Physiology

FLUID TRANSPORT IN THE BRAIN

Martin Kaag Rasmussen et al.

Summary: The brain has the ability to shift its gears between wakefulness and sleep, with information processing and behavior dominating in wakefulness and homeostatic functions prevailing during sleep. The brain relies on the glymphatic system, a fluid system comprised of the cerebrospinal fluid and perivascular spaces formed by astrocytic vascular endfeet, to clear waste products and maintain homeostasis. This system is especially active during sleep, driven by the cardiac cycle, respiration, and slow vasomotion.

PHYSIOLOGICAL REVIEWS (2022)

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Review Neurosciences

The Glymphatic System: A Novel Component of Fundamental Neurobiology

Lauren M. Hablitz et al.

Summary: The glymphatic system in the brain plays a key role in regulating interstitial fluid movement, waste clearance, and potentially brain immunity. Through the glymphatic system, there is potential to alter the local and global transport of signaling molecules and metabolites. Additionally, evidence suggests there is cross talk among the glymphatic system, cardiovascular system, gastrointestinal tract, and lymphatic system.

JOURNAL OF NEUROSCIENCE (2021)

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Article Multidisciplinary Sciences