Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 37, Pages 7843-7846Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01934f
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Funding
- Northeastern University
- National Science Foundation CAREER award [1453255]
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A solid-phase synthesis for nucleic acid-polymer amphiphiles is developed. Using this strategy, several DNA-b-polymer amphiphiles are synthesized, and their self-assembly in aqueous solution is investigated. This general method can in principle be extended to nearly all polymers synthesized by atom transfer radical polymerization to produce a variety of nucleic acid-polymer conjugates.
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