☆ 3.8 Review

Synthesis of end-user research to inform future multipurpose prevention technologies in sub-Saharan Africa: a scoping review

FRONTIERS IN REPRODUCTIVE HEALTH (2023)

Related references

Note: Only part of the references are listed.

Article Public, Environmental & Occupational Health

Couples' decision making regarding the use of multipurpose prevention technology (MPT) for pregnancy and HIV prevention

Marie C. D. Stoner et al.

Summary: This study conducted a secondary analysis of DCE data to understand couple decision making around the choice of MPTs for preventing HIV and pregnancy. Most couples had similar preferences or equal decision-making power. Couples with male influence were more likely to use contraceptive pills with the male partner's knowledge. Decision making was shared, but certain attributes were more likely to be dominated by male partners.

AIDS AND BEHAVIOR (2023)

Add to Collection

Article Public, Environmental & Occupational Health

Women Want Choices: Opinions from the Share.Learn.Shape Global Internet Survey About Multipurpose Prevention Technology (MPT) Products in Development

B. A. Friedland et al.

Summary: Women require multipurpose prevention technologies (MPTs) for simultaneous protection against sexually transmitted infections (STIs), including HIV, with or without contraception. The feedback from users during the early stages of product development is crucial for maximizing adoption and continuous usage. A global online survey conducted from April 2017 to December 2018 explored women's opinions on MPT formulations in development, preferences for long-acting or on-demand methods, and interest in contraceptive MPT versus products solely for HIV/STI prevention. Among the 630 women analyzed, the majority preferred a contraceptive MPT over HIV/STI prevention alone, with no specific preferences for a particular product or type.

AIDS AND BEHAVIOR (2023)

Add to Collection

Article Obstetrics & Gynecology

Contributions of side effects to contraceptive discontinuation and method switch among Kenyan women: a prospective cohort study

C. W. Rothschild et al.

Summary: This study aimed to determine the impact of specific contraceptive side effects on method switch and modern-method discontinuation among Kenyan women. The results showed that bleeding, weight changes, and sexual problems were associated with discontinuation of contraception, but many women continued to use despite experiencing side effects.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2022)

Add to Collection

Review Obstetrics & Gynecology

Values and preferences for contraception: A global systematic review

Ping Teresa Yeh et al.

Summary: This article conducts a systematic review of global contraceptive user values and preferences, aiming to identify and synthesize original research on users' perspectives and concerns about family planning methods. The study reveals diverse values and preferences among contraceptive users across different countries, while also identifying consistent core themes in their views.

CONTRACEPTION (2022)

Add to Collection

Article Multidisciplinary Sciences

Female and male partner perspectives on placebo Multipurpose Prevention Technologies (MPTs) used by women in the TRIO study in South Africa and Kenya

Laura Danielle Wagner et al.

Summary: This study explored men's reactions and preferences towards their partners' use of Multipurpose Prevention Technology (MPT) products. The findings showed that men wanted to be informed and educated about the products and expressed a high level of concern regarding optimizing ease of product adherence. They preferred long-acting, discreet products with minimal impact on sexual encounters.

PLOS ONE (2022)

Add to Collection

Article Immunology

Prospective study of oral pre-exposure prophylaxis initiation and adherence among young women in KwaZulu-Natal, South Africa

Leila E. Mansoor et al.

Summary: This study aims to explore the initiation and adherence of oral PrEP among young women in South Africa and its impact on HIV incidence. The study found that although the initiation rate and pill count adherence of PrEP were high, adherence measured by TFV-DP levels was low and early discontinuation was common.

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY (2022)

Add to Collection

Article Public, Environmental & Occupational Health

Couples' Preferences for 2 in 1 Multipurpose Prevention Technologies to Prevent Both HIV and Pregnancy: Results of a Discrete Choice Experiment in Uganda and Zimbabwe

Alexandra M. Minnis et al.

Summary: End-user input in biomedical product development is important for optimizing design. This study interviewed couples in Uganda and Zimbabwe to assess their preferences for multipurpose prevention technologies (MPTs) for HIV and pregnancy prevention. Results showed that couples preferred MPTs over male condoms and their choices were influenced by product form and dosing frequency. There were differences in preferences for side effects between the two countries.

AIDS AND BEHAVIOR (2022)

Add to Collection

Article Medicine, Research & Experimental

Acceptability of an intravaginal ring for simultaneously preventing HIV infection and pregnancy: Qualitative findings of the Kisumu combined ring study, 2019

Eleanor McLellan-Lemal et al.

Summary: Multipurpose prevention technology intravaginal rings (MPT IVRs) offer a potential solution for women's sexual and reproductive health needs. The study found that MPT IVRs were generally accepted by users, although concerns about physical discomforts and societal endorsement were identified. Personal choices in reproductive and sexual behaviors needed to align with sociocultural values for wider acceptance.

CONTEMPORARY CLINICAL TRIALS (2022)

Add to Collection

Article Immunology

Making the Case for Joint Decision-Making in Future Multipurpose Prevention Technology (MPT) Choice: Qualitative Findings on MPT Attribute Preferences from the CUPID Study (MTN-045)

Nivedita L. Bhushan et al.

Summary: Young women in sub-Saharan Africa are at high risk of HIV infection and unintended pregnancy. Multipurpose prevention technologies (MPTs) are promising products that aim to prevent both HIV and unintended pregnancy. Understanding the role of male partners in decision-making is crucial for ensuring the acceptability and use of MPTs.

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY (2022)

Add to Collection

Article Pediatrics

Global, regional, and national burdens of HIV and other sexually transmitted infections in adolescents and young adults aged 10-24 years from 1990 to 2019: a trend analysis based on the Global Burden of Disease Study 2019

Jing Zhang et al.

Summary: The incidence of HIV among adolescents and young adults globally has decreased, while other sexually transmitted infections (STIs) have increased and only started decreasing in 2011. The implementation of antiretroviral therapy and pre-exposure prophylaxis has contributed to the decrease in HIV incidence.

LANCET CHILD & ADOLESCENT HEALTH (2022)

Add to Collection

Article Medicine, General & Internal

PrEP acceptability and initiation among women engaged in sex work in Uganda: Implications for HIV prevention

Susan S. Witte et al.

Summary: Women engaged in sex work in Uganda are disproportionately affected by HIV, but many remain reluctant to use PrEP despite willingness. The study highlights the importance of family and friend support in destigmatizing sex work and PrEP use for women.

ECLINICALMEDICINE (2022)

Add to Collection

Article Public, Environmental & Occupational Health

Country-specific estimates of unintended pregnancy and abortion incidence: a global comparative analysis of levels in 2015-2019

Jonathan Marc Bearak et al.

Summary: Internationally comparable estimates of unintended pregnancy and abortion can shed light on disparities in sexual and reproductive health and autonomy. Country-specific estimates are crucial for international comparison and informing country-level policies.

BMJ GLOBAL HEALTH (2022)

Add to Collection

Review Pharmacology & Pharmacy

Advances in long-acting injectables, implants, and vaginal rings for contraception and HIV prevention

Sai Archana Krovi et al.

Summary: MPTs offer combined protection against HIV, STIs, and unintended pregnancy, with potential for simplified use and increased public health benefits. Significant progress has been made in the development of MPTs over the past decade, with the potential to grant sexual and reproductive health autonomy to women globally.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Add to Collection

Review Polymer Science

Multipurpose Prevention Technologies: Oral, Parenteral, and Vaginal Dosage Forms for Prevention of HIV/STIs and Unplanned Pregnancy

Isabella C. Young et al.

Summary: There is a high global prevalence of HIV, sexually transmitted infections (STIs), and unplanned pregnancies. Current preventative daily oral dosing regimens can be ineffective due to low patient adherence. Multipurpose prevention technologies (MPTs) in conjunction with sustained release delivery systems can reduce these high rates, providing users with efficacious, acceptable, and easily accessible technology.

POLYMERS (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Contraceptive Method Mix and HIV Risk Behaviors Among Kenyan Adolescent Girls and Young Women Seeking Family Planning Services: Implications for Integrating HIV Prevention

Edward Nyaboe et al.

Summary: The study found that in Kisumu, Kenya, LARC users more frequently engaged in transactional sex, and injectable users more frequently had condomless sex. There is a need to integrate HIV prevention services within family planning clinics, especially for AGYW.

FRONTIERS IN REPRODUCTIVE HEALTH (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Giving voice to the end-user: input on multipurpose prevention technologies from the perspectives of young women in Kenya and South Africa

Alexandra M. Minnis et al.

Summary: Unintended pregnancy and unmet need for modern contraception are major contributors to reproductive health disparities globally, especially in regions with high rates of HIV infection like sub-Saharan Africa. Research on future Multipurpose Prevention Technologies (MPTs) found high interest among participants, but anticipated side effects and various barriers exist. Therefore, attention to cultural contexts and research with end-users are essential to ensure acceptance of new MPT products and maximize public health benefits.

SEXUAL AND REPRODUCTIVE HEALTH MATTERS (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Trajectories of PrEP Adherence Among Young Women Aged 16 to 25 in Cape Town, South Africa

Marie C. D. Stoner et al.

Summary: Research has shown that there are two trajectories of PrEP adherence among adolescent girls and young women, with one group showing a decline in high early adherence and the other group demonstrating consistently low adherence. Factors influencing adherence include social support, logistical concerns, and the frequency of study visits. As a result, differentiated PrEP support should be provided based on individual needs.

AIDS AND BEHAVIOR (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Can healthcare choice be predicted using stated preference data?

E. W. de Bekker-Grob et al.

SOCIAL SCIENCE & MEDICINE (2020)

Add to Collection

Article Public, Environmental & Occupational Health

Efficacy is Not Everything: Eliciting Women's Preferences for a Vaginal HIV Prevention Product Using a Discrete-Choice Experiment

Erica N. Browne et al.

AIDS AND BEHAVIOR (2020)

Add to Collection

Article Immunology

End-user preference for and choice of four vaginally delivered HIV prevention methods among young women in South Africa and Zimbabwe: the Quatro Clinical Crossover Study

Elizabeth T. Montgomery et al.

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY (2019)

Add to Collection

Article Immunology

Young Women's Stated Preferences for Biomedical HIV Prevention: Results of a Discrete Choice Experiment in Kenya and South Africa

Alexandra M. Minnis et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2019)

Add to Collection

Article Obstetrics & Gynecology

Engaging study participants in interpreting results: lessons from the TRIO study in Kenya and South Africa

Kawango Agot et al.

INTERNATIONAL JOURNAL OF WOMENS HEALTH (2019)

Add to Collection

Article Immunology

The Tablets, Ring, Injections as Options (TRIO) study: what young African women chose and used for future HIV and pregnancy prevention

Ariane van der Straten et al.

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY (2018)

Add to Collection

Review Health Care Sciences & Services

Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach

Zachary Munn et al.

BMC MEDICAL RESEARCH METHODOLOGY (2018)

Add to Collection

Article Multidisciplinary Sciences

Perceptions of the Fabric - An exploratory study of a novel multi-purpose technology among women in Sub Saharan Africa

Nicole D. Laborde et al.

PLOS ONE (2018)

Add to Collection

Article Public, Environmental & Occupational Health

Young Women's Ratings of Three Placebo Multipurpose Prevention Technologies for HIV and Pregnancy Prevention in a Randomized, Cross-Over Study in Kenya and South Africa

Alexandra M. Minnis et al.

AIDS AND BEHAVIOR (2018)

Add to Collection

Article Public, Environmental & Occupational Health

A Randomized Crossover Study Evaluating the Use and Acceptability of the SILCS Diaphragm Compared to Vaginal Applicators for Vaginal Gel Delivery

Mags Beksinska et al.

AIDS AND BEHAVIOR (2018)

Add to Collection

Article Public, Environmental & Occupational Health

End-Users' Product Preference Across Three Multipurpose Prevention Technology Delivery Forms: Baseline Results from Young Women in Kenya and South Africa

Rachel Weinrib et al.

AIDS AND BEHAVIOR (2018)

Add to Collection

Article Public, Environmental & Occupational Health

Placing contraception at the centre of the HIV prevention agenda

Tamaryn L. Crankshaw et al.

AJAR-AFRICAN JOURNAL OF AIDS RESEARCH (2016)

Add to Collection

Meeting Abstract Immunology

Introduction of the SILCS Diaphragm as a Multipurpose Technology in South Africa: Potential Users, Perceived Benefits, and Barriers to Use

Cecilia Milford et al.

AIDS RESEARCH AND HUMAN RETROVIRUSES (2014)

Add to Collection

Article Obstetrics & Gynecology

Interest in multipurpose prevention of HIV and pregnancy: perspectives of women, men, health professionals and community stakeholders in two vaginal gel studies in southern Africa

C. Woodsong et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2014)

Add to Collection

Review Obstetrics & Gynecology

Making the case for multipurpose prevention technologies: the socio-epidemiological rationale

H. Boonstra et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2014)

Add to Collection

Article Demography

Reasons for Contraceptive Nonuse among Women Having Unmet Need for Contraception in Developing Countries

Gilda Sedgh et al.

STUDIES IN FAMILY PLANNING (2014)

Add to Collection

Review Pharmacology & Pharmacy

Designing a multipurpose technology for acceptability and adherence

Elizabeth E. Tolley et al.

ANTIVIRAL RESEARCH (2013)

Add to Collection

Article Multidisciplinary Sciences

How Much Demand for New HIV Prevention Technologies Can We Really Expect? Results from a Discrete Choice Experiment in South Africa

Fern Terris-Prestholt et al.

PLOS ONE (2013)

Add to Collection

Article Public, Environmental & Occupational Health

Use of modern contraception increases when more methods become available: analysis of evidence from 1982-2009

John Ross et al.

GLOBAL HEALTH-SCIENCE AND PRACTICE (2013)

Add to Collection

Review Immunology

Acceptability in microbicide and PrEP trials: current status and a reconceptualization

Barbara S. Mensch et al.

CURRENT OPINION IN HIV AND AIDS (2012)

Add to Collection

© Peeref 2019-2024. All rights reserved.