4.1 Review

Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials

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Article Chemistry, Medicinal

The effects of curcumin intake on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial

Mehrdad Mokhtari et al.

Summary: The intake of nanocurcumin significantly improved glycemic control and cholesterol levels in patients with diabetic foot ulcers, but did not have a significant impact on wound healing parameters.

PHYTOTHERAPY RESEARCH (2021)

Article Chemistry, Medicinal

Oral nano-curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease-19 patients: An open label nonrandomized clinical trial

Niloofar Saber-Moghaddam et al.

Summary: The study demonstrates that oral curcumin nano-formulation has significant effects in treating hospitalized COVID-19 patients, accelerating symptom relief and recovery. The treatment group showed superior outcomes in various aspects compared to the control group, including faster symptom resolution, higher oxygen saturation, and lymphocyte count.

PHYTOTHERAPY RESEARCH (2021)

Article Immunology

Nanocurcumin supplementation ameliorates Behcet's disease by modulating regulatory T cells: A randomized, double-blind, placebo-controlled trial

Samaneh Abbasian et al.

Summary: Nanocurcumin supplementation in Behcet's disease patients significantly increased Treg cells frequency, elevated the expression levels of related immunologic parameters, and reduced disease activity, showing promising potential for disease improvement.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects

Hyewon Chung et al.

Summary: In this study, the pharmacokinetics of two Theracurmin products and unformulated curcumin powder were compared. The results showed enhanced absorption of curcumin after the administration of Theracurmin compared to curcumin powder.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2021)

Article Biochemistry & Molecular Biology

A Presurgical Study of Curcumin Combined with Anthocyanin Supplements in Patients with Colorectal Adenomatous Polyps

Irene Maria Briata et al.

Summary: The combination of anthocyanins and curcumin appears to lead to a potentially favorable modulation of tissue biomarkers of inflammation and proliferation in colon adenomas.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Dentistry, Oral Surgery & Medicine

A clinicobiochemical evaluation of curcumin as gel and as buccal mucoadhesive patches in the management of oral submucous fibrosis

Aditi Chandrashekar et al.

Summary: This study evaluated the efficacy of topical curcumin gel and buccal mucoadhesive patches in managing oral submucous fibrosis (OSMF), finding both treatments effective in improving mouth opening and reducing burning sensation in patients. LDH levels were significantly higher in OSMF patients compared to healthy controls, but decreased after treatment with both curcumin gel and mucoadhesive patches.

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2021)

Article Endocrinology & Metabolism

Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective An- gioplasty; A Randomized Clinical Trial

Bijan Helli et al.

Summary: This study found that both curcumin and nano-curcumin have significant effects on improving lipid profiles, oxidative stress, and inflammatory factors related to heart in patients. Nano-curcumin showed better efficacy than curcumin in certain indicators.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2021)

Article Immunology

Miconia albicans and Curcuma longa herbal medicines positively modulate joint pain, function and inflammation in patients with osteoarthritis: a clinical study

Thiago P. O. Gomes et al.

Summary: This study found that the treatment of knee osteoarthritis with Curcuma longa and Miconia albicans had comparable effects to ibuprofen, significantly reducing pain and improving patient function.

INFLAMMOPHARMACOLOGY (2021)

Review Immunology

An updated advance of autoantibodies in autoimmune diseases

Ze Xiu Xiao et al.

Summary: Autoantibodies, generated by pathogenic B cells, are markers of autoimmune disorders and are considered clinical indicators. Different autoimmune diseases share similarities and differences, with women being more susceptible to these diseases compared to men.

AUTOIMMUNITY REVIEWS (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Food Science & Technology

Increasing Post-Digestive Solubility of Curcumin Is the Most Successful Strategy to Improve its Oral Bioavailability: A Randomized Cross-Over Trial in Healthy Adults and In Vitro Bioaccessibility Experiments

Sandra Flory et al.

Summary: This study compared the oral bioavailability of curcumin from different formulations and found a significant increase in bioavailability for micellar curcumin and curcumin-gamma-cyclodextrin complexes, likely due to increased post-digestive stability and solubility. However, strategies targeting post-absorptive processes appear to be ineffective in improving the bioavailability of curcumin.

MOLECULAR NUTRITION & FOOD RESEARCH (2021)

Article Urology & Nephrology

The effects of nanocurcumin supplementation on inflammation in hemodialysis patients: A randomized controlled trial

Golchin Vafadar-Afshar et al.

Summary: The study showed that nanocurcumin supplementation reduced serum levels and gene expression of IL-6 and TNF-alpha in hemodialysis patients. The results suggest the feasibility and potential clinical benefits of nanocurcumin treatment in reducing inflammation in hemodialysis patients.

HEMODIALYSIS INTERNATIONAL (2021)

Article Food Science & Technology

Effectiveness of the piperine-supplemented Curcuma longa L. in metabolic control of patients with type 2 diabetes: a randomised double-blind placebo-controlled clinical trial

Joana Furtado de Figueiredo Neta et al.

Summary: The study provides strong evidence that Curcuma longa L. can effectively reduce metabolic levels in individuals with diabetes, especially in the glycemic and triglyceride control of patients with type 2 diabetes.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2021)

Article Nutrition & Dietetics

Curcuma longa extract improves serum inflammatory markers and mental health in healthy participants who are overweight: a randomized, double-blind, placebo-controlled trial

Ryusei Uchio et al.

Summary: The study found that the dietary spice Curcuma longa containing anti-inflammatory turmeronols can help improve chronic low-grade inflammation, as well as enhance mental health and mood disturbance.

NUTRITION JOURNAL (2021)

Article Oncology

Caries effected dentin disinfection using Ozone, methylthioninium chloride and turmeric activated by photodynamic therapy on bond integrity of resin-modified glass ionomer cement

Rana Sulaiman Al-Hamdan

Summary: Curcumin combined with ozone has the potential to be used as a disinfectant in caries affected dentin, improving SBS to RMGIC. Chlorhexidine demonstrates low microleakage scores and decreases bond integrity.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

Article Chemistry, Medicinal

Effects of curcumin on menstrual pattern, premenstrual syndrome, and dysmenorrhea: A triple-blind, placebo-controlled clinical trial

Afsane Bahrami et al.

Summary: This study found that curcumin had a comparable effect to placebo in alleviating symptoms of PMS and dysmenorrhea. Further research with larger samples, higher doses of curcumin for longer durations, and perhaps in combination therapy is recommended for validation.

PHYTOTHERAPY RESEARCH (2021)

Article Orthopedics

Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study

X. Liu et al.

Summary: The RADIANT study aimed to investigate the efficacy and safety of a complementary medicine supplement combination in people with hand osteoarthritis. However, the results showed no significant differences in symptomatic relief between the two groups over 12 weeks, suggesting that the supplement combination might not be effective for treating hand pain in people with HOA.

OSTEOARTHRITIS AND CARTILAGE (2021)

Article Medicine, Research & Experimental

Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol

Shubha Singhal et al.

Summary: The study results suggest that bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis, while also being safer and more effective in reducing CRP and TNF-alpha levels.

TRIALS (2021)

Article Nutrition & Dietetics

Functional Food Components, Intestinal Permeability and Inflammatory Markers in Patients with Inflammatory Bowel Disease

Joana Franco Lacerda et al.

Summary: The study aimed to evaluate the effect of food components on intestinal permeability and inflammatory markers in individuals with IBD. While the specific impact of food components was inconclusive, there was a trend observed in the reduction of inflammatory parameters and gastrointestinal symptom prevalence. More controlled intervention studies with diet plans including potentially beneficial food components for intestinal barrier integrity are warranted.

NUTRIENTS (2021)

Article Environmental Sciences

A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Curcumin (Curcuma longa), Boswellia (Boswellia serrata), and French Maritime Pine Bark (Pinus pinaster)

Emily K. Donovan et al.

Summary: This study found that curcumin and maritime pine may help alleviate symptoms of Gulf War Illness, while boswellia was not significantly more effective than placebo. Further research is needed to determine the efficacy, strength, durability of effects, and optimal dosage of these botanical compounds for individuals with GWI.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Article Oncology

Multicenter randomized phase II study comparing docetaxel plus curcumin versus docetaxel plus placebo in first-line treatment of metastatic castration-resistant prostate cancer

Judith Passildas-Jahanmohan et al.

Summary: Despite good compliance and verified absorption of curcumin, the study showed no significant difference in progression-free survival between the curcumin and placebo groups, as well as in the secondary endpoints such as PSA response rate, overall survival, and quality of life. Consequently, the study was discontinued due to lack of efficacy.

CANCER MEDICINE (2021)

Review Chemistry, Multidisciplinary

Mesenchymal Stem Cells for Neurological Disorders

Anna Andrzejewska et al.

Summary: Neurological disorders pose a growing burden as society ages, with stem cell-based regenerative medicine offering a promising approach. Researchers are studying the application of MSCs to various neurological diseases and focusing on the delivery of stem cells to the brain as an essential and understudied challenge.

ADVANCED SCIENCE (2021)

Article Endocrinology & Metabolism

The effect of turmeric on lipid profile, malondialdehyde, liver echogenicity and enzymes among patients with nonalcoholic fatty liver disease: a randomized double blind clinical trial

Maryam Jarhahzadeh et al.

Summary: This study demonstrated that turmeric supplementation can effectively reduce liver enzymes, lipid profiles, and MDA levels in NAFLD patients. The results suggest that daily consumption of turmeric may be beneficial in managing NAFLD and decreasing serum liver enzyme levels.

DIABETOLOGY & METABOLIC SYNDROME (2021)

Article Cardiac & Cardiovascular Systems

Cardiovascular Disease in Chronic Kidney Disease Pathophysiological Insights and Therapeutic Options

Joachim Jankowski et al.

Summary: Patients with chronic kidney disease face an increased risk of cardiovascular events, with advanced CKD stages significantly elevating the risk. Cardiovascular events, rather than end-stage kidney disease, are the leading cause of death in this high-risk population, and CKD causes a proinflammatory state that affects the cardiovascular system.

CIRCULATION (2021)

Article Oncology

Cancer statistics for the year 2020: An overview

Jacques Ferlay et al.

Summary: The study briefly reviews the methods and data sources used in compiling the IARC GLOBOCAN cancer statistics for 2020 and summarizes the main results. It estimated that there were nearly 19.3 million new cancer cases and almost 10 million cancer deaths worldwide in 2020, with the most commonly diagnosed cancers being female breast cancer and lung cancer, and the most common causes of cancer death being lung cancer and liver cancer.

INTERNATIONAL JOURNAL OF CANCER (2021)

Article Nutrition & Dietetics

Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study

Pascale Fanca-Berthon et al.

Summary: The study suggests that the novel natural dried colloidal suspension of turmeric provides significantly better absorption of curcuminoids compared to other turmeric formulations, particularly when compared to a high dose of standard extract. Both unconjugated and conjugated curcuminoid absorption levels were higher with the dried colloidal suspension than with other formulations, and no significant adverse events were reported.

JOURNAL OF NUTRITION (2021)

Article Pharmacology & Pharmacy

Comparative bioavailability of curcuminoids from a water-dispersible high curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over, comparative, pharmacokinetic study

Shefali Thanawala et al.

Summary: WDTE6ON shows higher absorption and comparable exposure for free curcumin, total curcumin, and total curcuminoids at a 10-fold lower dose compared to STE95, suggesting its potential as an alternative to turmeric extract.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2021)

Article Chemistry, Medicinal

The effects of nano-curcumin supplementation on glycemic control, blood pressure, lipid profile, and insulin resistance in patients with the metabolic syndrome: A randomized, double-blind clinical trial

Zohre Bateni et al.

Summary: This study demonstrated that supplementation with nano-micelle curcumin significantly reduced serum triglyceride levels and HOMA-beta in MetS patients. However, there were no significant differences in other anthropometric measurements, blood pressure, and lipid profile variables at the end of the study.

PHYTOTHERAPY RESEARCH (2021)

Article Chemistry, Medicinal

The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design

Majid Karandish et al.

Summary: Management of prediabetes is crucial in preventing type-2 diabetes. This clinical trial examined the effects of curcumin and zinc supplementation on glycemic parameters, showing improvements in fasting plasma glucose, 2-hour postprandial glucose, HbA1C, insulin sensitivity, and insulin resistance. Dietary intake, physical activity, weight, and beta-cell function did not significantly differ among the groups after the intervention.

PHYTOTHERAPY RESEARCH (2021)

Article Food Science & Technology

Recent advances to improve curcumin oral bioavailability

Saman Sabet et al.

Summary: The oral delivery of curcumin is limited due to its low water solubility, low bioaccessibility, and fast degradation in the gastrointestinal tract. Recent advances in new delivery systems have shown potential in improving curcumin oral bioavailability, particularly through approaches such as curcumin-lipid conjugates and mucoadhesive delivery systems.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Review Chemistry, Medicinal

Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure

Osama A. Badary et al.

Summary: COVID-19 has caused a major global health crisis, and while few effective drugs have emerged, the main active ingredient of black seed oil, Thymoquinone (TQ), has shown promising antiviral, anti-inflammatory, and immunomodulatory properties that may help combat the virus. Studies have also demonstrated TQ's potential protective capabilities against various chronic diseases and conditions, highlighting its potential therapeutic effects in the context of the COVID-19 pandemic.

DRUG DESIGN DEVELOPMENT AND THERAPY (2021)

Article Biology

An incremental learning approach to automatically recognize pulmonary diseases from the multi-vendor chest radiographs

Mehreen Sirshar et al.

Summary: The study explores the use of deep learning systems to diagnose pulmonary diseases, but the challenges of large-scale data and rare diseases limit the application of such systems.

COMPUTERS IN BIOLOGY AND MEDICINE (2021)

Article Environmental Sciences

Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors

Christina Lombardi et al.

Summary: The study suggests that residential proximity to agricultural pesticide applications during pregnancy may increase the risk of childhood central nervous system tumors. Elevated risks were observed for several specific pesticides in relation to different types of childhood brain tumors.

ENVIRONMENTAL RESEARCH (2021)

Article Medicine, Research & Experimental

Nanocurcumin improves Treg cell responses in patients with mild and severe SARS-CoV2

Safa Tahmasebi et al.

Summary: The study showed that Nanocurcumin effectively increased the number of Treg cells and their mediated factors in both mild and severe COVID-19 patients, suggesting it may be a promising therapeutic agent for rehabilitating COVID-19 infected patients.

LIFE SCIENCES (2021)

Review Endocrinology & Metabolism

Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus

Daniel Ferguson et al.

Summary: NAFLD is the most prevalent liver disease worldwide, with no approved pharmacological therapies available. The spectrum of severity ranges from steatosis to NASH, which is linked to increased risks of liver cancer and cirrhosis. Therefore, a holistic approach and ongoing therapeutic options are necessary to address the global health burden of these diseases.

NATURE REVIEWS ENDOCRINOLOGY (2021)

Article Oncology

Efficacy of Rose Bengal and Curcumin mediated photodynamic therapy for the treatment of denture stomatitis in patients with habitual cigarette smoking: A randomized controlled clinical trial

Nawaf Labban et al.

Summary: This study found that Curcumin and Rose Bengal-mediated photodynamic therapy is as effective as topical Nystatin therapy for the intervention of denture stomatitis among cigarette smokers. Significant decrease in CFU/mL scores were observed in Group-I and Group-II at the end of the interventions and on the 12-week follow-up. The clinical efficacy rates for Group-I, II, and III were 53%, 51%, and 49% respectively.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

Article Chemistry, Medicinal

The effect of nanomicelle curcumin supplementation and Nigella sativa oil on the expression level of miRNA-21, miRNA-422a, and miRNA-503 gene in postmenopausal women with low bone mass density: A randomized, triple-blind, placebo-controlled clinical trial with factorial design

Azizeh Farshbaf-Khalili et al.

Summary: This study found that supplementation with Nigella sativa oil and Nigella sativa oil-curcumin can increase the expression level of miRNA-21 in postmenopausal women with low bone density.

PHYTOTHERAPY RESEARCH (2021)

Article Chemistry, Medicinal

A triple-blind, placebo-controlled, randomized clinical trial to evaluate the effect of curcumin-containing nanomicelles on cellular immune responses subtypes and clinical outcome in COVID-19 patients

Mehdi Hassaniazad et al.

Summary: This study showed that nano-curcumin may accelerate recovery of the acute inflammatory phase in COVID-19 patients by modulating inflammatory immune responses, indicating its potential effectiveness in controlling inflammatory responses in inflammatory diseases, including COVID-19.

PHYTOTHERAPY RESEARCH (2021)

Article Chemistry, Medicinal

Effects of curcuminoids on inflammatory and oxidative stress biomarkers and clinical outcomes in critically ill patients: A randomized double-blind placebo-controlled trial

Hoda Zahedi et al.

Summary: The study showed that short-term supplementation with curcuminoids can significantly reduce inflammation levels, improve clinical outcomes, and enhance nutritional status in patients with TBI.

PHYTOTHERAPY RESEARCH (2021)

Article Nutrition & Dietetics

Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial

Helena Tiekou Lorinczova et al.

Summary: This study aimed to evaluate the influence of a formulated bioavailable form of curcumin on acute iron absorption and status, and the results showed that the formulated curcumin did not negatively impact acute iron absorption in healthy humans, regardless of the dose used.

NUTRIENTS (2021)

Review Pharmacology & Pharmacy

Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

Meike Kaehler et al.

Summary: The use of small molecules, such as tyrosine kinase inhibitors (TKIs), is crucial in targeted anti-cancer therapy, especially in treating chronic myelogenous leukemia (CML). While TKIs like imatinib or nilotinib show high effectiveness in CML patients, treatment failure can still occur in some cases, either dependent or independent from the BCR-ABL1 kinase.

FRONTIERS IN PHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial

Kirti S. Pawar et al.

Summary: The study found that using curcumin/piperine treatment in COVID-19 can improve symptoms, reduce deterioration, and improve clinical outcomes. In addition, curcumin/piperine treatment also appears to shorten hospitalization for severe patients and reduce mortality.

FRONTIERS IN PHARMACOLOGY (2021)

Article Clinical Neurology

ProspeCtive study to evaluate efficacy, safety and tOlerability of dietary supplemeNT of Curcumin (BCM95) in subjects with Active relapsing MultIple Sclerosis treated with subcutaNeous Interferon beta 1a 44 mcg TIW (CONTAIN): A randomized, controlled trial

Maria Petracca et al.

Summary: The study found that although the IFN-curcumin group had a lower proportion of patients with inflammatory lesions at month 12 compared to the IFN-placebo group, this difference was not confirmed at month 24. There was no difference between the two treatment groups in terms of relapses, disability progression, other MRI metrics of inflammation, and MRI changes suggestive of ongoing neurodegeneration. No difference in the rate and nature of adverse events was observed between the two treatment groups.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2021)

Article Food Science & Technology

Oral nano-curcumin formulation efficacy in the management of mild to moderate outpatient COVID-19: A randomized triple-blind placebo-controlled clinical trial

Reza Ahmadi et al.

Summary: The study shows that oral nanoformulation of curcumin can help mild to moderate COVID-19 patients recover faster, reducing chills, cough, and smell and taste disturbances. The treatment group had lower CRP serum levels and significantly higher lymphocyte counts, with no significant adverse reactions reported.

FOOD SCIENCE & NUTRITION (2021)

Article Andrology

Combination therapy with curcumin plus tamsulosin and finasteride in the treatment of men with benign prostatic hyperplasia: a single center, randomized control study

Jing Qiao et al.

Summary: The study found that the combined use of curcumin, tamsulosin, and finasteride is more beneficial for BPH patients, reducing periprostatic fat, protecting erectile function, improving urinary retention symptoms, and quality of life.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2021)

Article Public, Environmental & Occupational Health

Global Epidemiology of HIV/AIDS: A Resurgence in North America and Europe

Romona D. Govender et al.

Summary: This study aimed to assess global trends in HIV/AIDS and found that while many countries have decreasing incidence rates, some countries like Russia, Ukraine, Portugal, Brazil, Spain and the United States have been experiencing rising rates of new cases since 2010. Globally, there are about 5000 new infections daily, with approximately 500 of them being children. Mortality rates are decreasing globally while prevalence continues to rise.

JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH (2021)

Article Integrative & Complementary Medicine

Effects of nanomicelle curcumin capsules on prevention and treatment of oral mucosits in patients under chemotherapy with or without head and neck radiotherapy: a randomized clinical trial

Seyed Javad Kia et al.

Summary: The study investigated the effects of nanomicelle Curcumin on oral mucositis related to chemotherapy and radiotherapy, showing significant reduction in severity and pain of oral mucositis in patients receiving nanomicelle Curcumin compared to the control group. The results suggest that nanomicelle Curcumin is effective in prevention and treatment of oral mucositis induced by chemotherapy and radiotherapy.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2021)

Review Food Science & Technology

Dietary phytochemicals modulate intestinal epithelial barrier dysfunction and autoimmune diseases

Kumar Ganesan et al.

Summary: This review focuses on modulators of intestinal epithelial barrier dysfunction with effects on autoimmune disorders, discussing the impact of dietary phytochemicals on autoimmune diseases.

FOOD FRONTIERS (2021)

Article Clinical Neurology

Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial

Jennifer Ngolab et al.

Summary: The study compared retinal and cerebral amyloid deposits in clinically normal individuals with high and low amyloid levels. It found a greater number of retinal spots in individuals with high amyloid levels, and a positive correlation between retinal spots and brain amyloid. Larger sample sizes are needed to fully understand the relationship between amyloid PET and retinal amyloid deposition.

ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING (2021)

Article Pharmacology & Pharmacy

Efficacy of Curcumin and Topical Steroids in the Treatment for Oral Submucous Fibrosis: A Comparative study

T. A. Deepak et al.

Summary: This study aimed to evaluate the efficacy of curcumin in treating OSMF, assess the efficacy of topical steroids, and compare the two treatments. The results demonstrated that curcumin was more efficient than topical steroids for alleviating the clinical findings of OSMF.

JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2021)

Article Pharmacology & Pharmacy

Comparative Evaluation of Anti-Inflammatory Efficacy of Turmeric and Chlorhexidine Gel as an Adjunct to Scaling and Root Planing in the Treatment of Gingivitis

Swati Singh et al.

Summary: The study compared the anti-plaque efficacy and anti-inflammatory potential of turmeric gel with 0.2% chlorhexidine gel in combination with scaling and root planing. The results showed that turmeric gel had a slightly lower anti-plaque property compared to chlorhexidine gel, but their effect on reducing gingival inflammation was equal. Participants also found turmeric gel to be more acceptable and biocompatible.

JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2021)

Article Medicine, Research & Experimental

Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use

Yanhong Jessika Hu et al.

Summary: Recruitment was challenging due to widespread expectations for antibiotics, but patients with mild diarrhoea accepted trying an alternative. Most interviewed participants were surprised by their quick recovery without antibiotics in this trial, indicating the effectiveness of alternative therapies.

PILOT AND FEASIBILITY STUDIES (2021)

Article Endocrinology & Metabolism

Effect of eight-week curcumin supplementation with endurance training on glycemic indexes in middle age women with type 2 diabetes in Iran, A preliminary study

Seyedeh Katayoun Zamani et al.

Summary: The findings of this study demonstrate that 8 weeks of curcumin supplementation and endurance training significantly improved glycemic indexes in middle-aged women with type 2 diabetes.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2021)

Article Pharmacology & Pharmacy

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Assessing Efficacy and Safety of a Novel Low-Dose Turmeric Extract Formulation in Healthy Adults with Chronic Knee Pain

Shefali Thanawala et al.

Summary: The water-dispersible turmeric formulation showed efficacy in alleviating symptoms of chronic knee pain, improving joint function, and was well tolerated and safe.

CLINICAL PHARMACOLOGY-ADVANCES AND APPLICATIONS (2021)

Article Nursing

The Effect of Curcumin Ointment on the Quality of Life of Older Adults with Knee Osteoarthritis: A Randomized Placebo Clinical Trial

Neda Jamali et al.

Summary: The study found that the use of curcumin ointment can significantly improve the quality of life in older adults with knee osteoarthritis. Therefore, this ointment may be considered as a complementary therapy to improve the QOL of patients with KO.

NURSING AND MIDWIFERY STUDIES (2021)

Review Chemistry, Medicinal

From Simple Mouth Cavities to Complex Oral Mucosal Disorders-Curcuminoids as a Promising Therapeutic Approach

Sosmitha Girisa et al.

Summary: Oral diseases are common worldwide and require safe and effective treatments. Curcumin, a natural polyphenol with diverse biological effects, shows promise in treating various oral conditions and has been studied in both in vitro and in vivo studies, as well as in clinical trials.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Article Nutrition & Dietetics

Effect of Curcumin on Serum Urate in Asymptomatic Hyperuricemia: A Randomized Placebo-Controlled Trial

Pannipa Bupparenoo et al.

Summary: The study found that curcumin was not superior to placebo in reducing serum urate and increasing urine uric acid clearance.

JOURNAL OF DIETARY SUPPLEMENTS (2021)

Article Medicine, General & Internal

A randomized controlled trial of combination of peppermint, lavender, and turmeric oil for antipruritic agent in pregnant women

Fransisca Retno Asih et al.

Summary: The study found that pregnant women who used blending oil had a higher reduction in pruritus compared to those using a placebo, with 83% of subjects experiencing a reduction of over 25 mm. Pregnant women using a placebo had a six times higher risk of experiencing pruritus than those using blending oil.

MEDICAL JOURNAL OF INDONESIA (2021)

Article Urology & Nephrology

Multicentre International Study for the Prevention with iAluRil of Radio-induced Cystitis (MISTIC): A Randomised Controlled Study

Juan Palou Redorta et al.

Summary: The study suggests that the use of hyaluronic acid and chondroitin sulfate may reduce urinary symptoms and improve quality of life during radiotherapy for prostate cancer.

EUROPEAN UROLOGY OPEN SCIENCE (2021)

Article Dentistry, Oral Surgery & Medicine

Effects of oral moisturizing gel containing propolis following head and neck radiotherapy: randomized controlled pilot trial

Ryoma Nakao et al.

Summary: The study demonstrated that topical administration of propolis gel can significantly decrease the amount of Porphyromonas gingivalis in saliva and relieve oral pain in patients with head and neck cancer. Further larger-scale clinical trials are needed to confirm the clinical efficacy of propolis gel in reducing radiotherapy-related oral complications.

BDJ OPEN (2021)

Review Psychology, Clinical

Psychological interventions to prevent the onset of depressive disorders: A meta-analysis of randomized controlled trials

Pim Cuijpers et al.

Summary: Preventive psychological interventions for individuals without depression can significantly reduce the risk of developing depressive disorders, providing a promising approach to reduce the global disease burden of depression.

CLINICAL PSYCHOLOGY REVIEW (2021)

Article Peripheral Vascular Disease

Curcumin's Effect on Inflammatory Response following Percutaneous Coronary Intervention in Adult Patients with Stable Coronary Heart Disease

Todung Silalahi et al.

Summary: This research indicates that oral administration of curcumin has a certain effect in reducing inflammatory response post-PCI in patients with stable CHD, especially in significantly lowering serum hsCRP and sCD40L levels within 48 hours.

INTERNATIONAL JOURNAL OF ANGIOLOGY (2021)

Article Nutrition & Dietetics

Cost-Effectiveness of Passion Fruit Albedo versus Turmeric in the Glycemic and Lipaemic Control of People with Type 2 Diabetes: Randomized Clinical Trial

Danilo Ferreira de Sousa et al.

Summary: The flour made from yellow passion fruit albedo showed better efficacy in reducing fasting blood sugar levels compared to placebo and long turmeric merged with piperine. The group using long turmeric with piperine showed significant improvements in reducing HOMA-IR and serum triglyceride levels.

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2021)

Article Dentistry, Oral Surgery & Medicine

Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: Randomized, placebo-controlled, double-blind split-mouth clinical trial

Cindy Grace Perez-Pacheco et al.

Summary: The study found that a single local application of nanoencapsulated curcumin did not have additional benefits to non-surgical periodontal treatment (NPT) in diseased sites.

CLINICAL ORAL INVESTIGATIONS (2021)

Article Dentistry, Oral Surgery & Medicine

Oral nano-curcuminon gingival inflammation in patients with gingivitis and mild periodontitis

Meisam Malekzadeh et al.

Summary: This study evaluated the effects of oral nano-curcumin on gingival inflammation in patients with gingivitis and mild periodontitis, finding that nano-curcumin has positive effects on reducing inflammation and gingival bleeding. Nano-curcumin capsules with systemic target site have higher bioavailability than topical forms.

CLINICAL AND EXPERIMENTAL DENTAL RESEARCH (2021)

Article Nutrition & Dietetics

Curcumin Improves Delayed Onset Muscle Soreness and Postexercise Lactate Accumulation

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Investigation of the Effects of Curcumin on Serum Cytokines in Obese Individuals: A Randomized Controlled Trial

Shiva Ganjali et al.

SCIENTIFIC WORLD JOURNAL (2014)

Article Biotechnology & Applied Microbiology

Human Pharmacokinetics of High Dose Oral Curcumin and Its Effect on Heme Oxygenase-1 Expression in Healthy Male Subjects

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BIOMED RESEARCH INTERNATIONAL (2014)

Editorial Material Biotechnology & Applied Microbiology

Novel Medicines and Strategies in Cancer Treatment and Prevention

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BIOMED RESEARCH INTERNATIONAL (2014)

Article Medicine, General & Internal

Novel Therapeutic Approach for the Treatment of Periodontitis by Curcumin

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JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2014)

Review Endocrinology & Metabolism

Anti-Hyperglycemic and Insulin Sensitizer Effects of Turmeric and Its Principle Constituent Curcumin

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INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2014)

Article Medicine, General & Internal

Evaluation of Efficacy of Curcumin as an Add-on therapy in Patients of Bronchial Asthma

Afroz Abidi et al.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2014)

Article Pharmacology & Pharmacy

Drinkable Preparation of Theracurmin Exhibits High Absorption Efficiency—A Single-Dose, Double-Blind, 4-Way Crossover Study

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BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)

Article Chemistry, Medicinal

Novel racemic tetrahydrocurcuminoid dihydropyrimidinone analogues as potent acetylcholinesterase inhibitors

Sarawalee Arunkhamkaew et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Integrative & Complementary Medicine

The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study

Sang-Wook Kim et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)

Review Pharmacology & Pharmacy

Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers

Bharat B. Aggarwal et al.

BRITISH JOURNAL OF PHARMACOLOGY (2013)

Review Pharmacology & Pharmacy

Molecular understanding of curcumin in diabetic nephropathy

Vivian Soetikno et al.

DRUG DISCOVERY TODAY (2013)

Article Nutrition & Dietetics

Effects of various food ingredients on gall bladder emptying

L. Marciani et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2013)

Article Integrative & Complementary Medicine

A Pilot Study on Intravesical Administration of Curcumin for Cystitis Glandularis

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EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)

Article Gastroenterology & Hepatology

Tolerability of Curcumin in Pediatric Inflammatory Bowel Disease: A Forced-Dose Titration Study

David L. Suskind et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2013)

Review Food Science & Technology

Multitargeting by turmeric, the golden spice: From kitchen to clinic

Subash C. Gupta et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2013)

Review Food Science & Technology

Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric

Bharat B. Aggarwal et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2013)

Article Peripheral Vascular Disease

Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

Nobuhiko Akazawa et al.

ARTERY RESEARCH (2013)

Article Cardiac & Cardiovascular Systems

Effects of Curcuminoids on Frequency of Acute Myocardial Infarction After Coronary Artery Bypass Grafting

Wanwarang Wongcharoen et al.

AMERICAN JOURNAL OF CARDIOLOGY (2012)

Review Pharmacology & Pharmacy

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

Subash C. Gupta et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2012)

Article Endocrinology & Metabolism

Curcumin Extract for Prevention of Type 2 Diabetes

Somlak Chuengsamarn et al.

DIABETES CARE (2012)

Article Dermatology

High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus

Nita Chainani-Wu et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2012)

Article Surgery

Overall-Mouth Disinfection by Photodynamic Therapy Using Curcumin

Natalia Costa Araujo et al.

PHOTOMEDICINE AND LASER SURGERY (2012)

Article Nutrition & Dietetics

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people

Robert A. DiSilvestro et al.

NUTRITION JOURNAL (2012)

Article Nutrition & Dietetics

Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women

Nobuhiko Akazawa et al.

NUTRITION RESEARCH (2012)

Review Cell Biology

Treating Human Autoimmunity: Current Practice and Future Prospects

Michael D. Rosenblum et al.

SCIENCE TRANSLATIONAL MEDICINE (2012)

Article Pharmacology & Pharmacy

Innovative Preparation of Curcumin for Improved Oral Bioavailability

Hiroki Sasaki et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)

Article Food Science & Technology

The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids

Mohamed A. El-Moselhy et al.

FOOD AND CHEMICAL TOXICOLOGY (2011)

Article Agriculture, Multidisciplinary

PLGA Nanoparticles Improve the Oral Bioavailability of Curcumin in Rats: Characterizations and Mechanisms

Xiaoxia Xie et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)

Article Plant Sciences

Comparative Absorption of a Standardized Curcuminoid Mixture and Its Lecithin Formulation

John Cuomo et al.

JOURNAL OF NATURAL PRODUCTS (2011)

Review Biochemistry & Molecular Biology

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

Purusotam Basnet et al.

MOLECULES (2011)

Review Biochemistry & Molecular Biology

Multitargeting by curcumin as revealed by molecular interaction studies

Subash C. Gupta et al.

NATURAL PRODUCT REPORTS (2011)

Review Oncology

Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

Muthu K. Shanmugam et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)

Article Oncology

Effect of imatinib therapy with and without turmeric powder on nitric oxide levels in chronic myeloid leukemia

Veena S Ghalaut et al.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2011)

Review Pharmacology & Pharmacy

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer

Hareesh B. Nair et al.

BIOCHEMICAL PHARMACOLOGY (2010)

Article Medical Laboratory Technology

Improvement in oxidative stress and antioxidant parameters in β-thalassemia/Hb E patients treated with curcuminoids

Ruchaneekorn W. Kalpravidh et al.

CLINICAL BIOCHEMISTRY (2010)

Article Toxicology

Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal

Jaydip Biswas et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2010)

Article Immunology

Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients

Chuchart Koosirirat et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2010)

Article Nutrition & Dietetics

Increase in Plasma Concentrations of Geranylgeranoic Acid after Turmeric Tablet Intake by Healthy Volunteers

Maiko Mitake et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2010)

Article Oncology

Curcumin and Gemcitabine in Patients With Advanced Pancreatic Cancer

Ron Epelbaum et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2010)

Article Nutrition & Dietetics

Effects of Curcuma longa (turmeric) on postprandial plasma glucose and insulin in healthy subjects

Jennie Wickenberg et al.

NUTRITION JOURNAL (2010)

Review Pharmacology & Pharmacy

Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?

Jayaraj Ravindran et al.

AAPS JOURNAL (2009)

Article Gastroenterology & Hepatology

Effect of Dietary Turmeric on Breath Hydrogen

Akito Shimouchi et al.

DIGESTIVE DISEASES AND SCIENCES (2009)

Article Integrative & Complementary Medicine

Clinical Evaluation of an Indian Polyherbal Topical Formulation in the Management of Eczema

Ranjan C. Rawal et al.

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2009)

Article Integrative & Complementary Medicine

Efficacy and Safety of Curcuma domestica Extracts in Patients with Knee Osteoarthritis

Vilai Kuptniratsaikul et al.

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2009)

Article Public, Environmental & Occupational Health

The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

Alessandro Liberati et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2009)

Article Nutrition & Dietetics

Effect of Exclusion Diet with Nutraceutical Therapy in Juvenile Crohn's Disease

Alfred E. Slonim et al.

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2009)

Review Medicine, General & Internal

Acute Coronary Syndromes: Diagnosis and Management, Part I

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MAYO CLINIC PROCEEDINGS (2009)

Article Clinical Neurology

Effect of Oral Curcumin on Dejerine-Sottas Disease

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PEDIATRIC NEUROLOGY (2009)

Article Nutrition & Dietetics

Effect of cinnamon and turmeric on urinary oxalate excretion, plasma lipids, and plasma glucose in healthy subjects

Minghua Tang et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)

Article Biochemistry & Molecular Biology

Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300

Min-Jung Ryu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Editorial Material Pharmacology & Pharmacy

Curcumin as Curecumin:: From kitchen to clinic

Ajay Goel et al.

BIOCHEMICAL PHARMACOLOGY (2008)

Article Oncology

Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects

Shaiju K. Vareed et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)

Review Biochemistry & Molecular Biology

Curcumin: From ancient medicine to current clinical trials

H. Hatcher et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Oncology

Phase II trial of curcumin in patients with advanced pancreatic cancer

Navneet Dhillon et al.

CLINICAL CANCER RESEARCH (2008)

Article Food Science & Technology

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

E. Olatunde Farombi et al.

FOOD AND CHEMICAL TOXICOLOGY (2008)

Review Plant Sciences

Potential of Spice-Derived Phytochemicals for Cancer Prevention

Bharat B. Aggarwal et al.

PLANTA MEDICA (2008)

Article Gastroenterology & Hepatology

Prevention of hepatotoxicity due to anti tuberculosis treatment: A novel integrative approach

Meghna R. Adhvaryu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2008)

Article Pharmacology & Pharmacy

Curcumin effects on blood lipid profile in a 6-month human study

Larry Baum et al.

PHARMACOLOGICAL RESEARCH (2007)

Review Medicine, Research & Experimental

Bioavailability of curcumin: Problems and promises

Preetha Anand et al.

MOLECULAR PHARMACEUTICS (2007)

Article Pharmacology & Pharmacy

Unexpected effect of concomitantly administered curcumin on the pharmacokinetics of talinolol in healthy Chinese volunteers

He Juan et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2007)

Article Biochemistry & Molecular Biology

Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells

Hyun-Ock Pae et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2007)

Article Chemistry, Medicinal

The safety and efficacy of a dietary herbal supplement and gallic acid for weight loss

Andrew T. Roberts et al.

JOURNAL OF MEDICINAL FOOD (2007)

Article Biochemistry & Molecular Biology

Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells

Hyun-Ock Pae et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Medicine, Research & Experimental

Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma Activation

Asha Jacob et al.

PPAR RESEARCH (2007)

Article Nutrition & Dietetics

Chili, but not turmeric, inhibits iron absorption in young women from an iron-fortified composite meal

Siriporn Tuntipopipat et al.

JOURNAL OF NUTRITION (2006)

Article Gastroenterology & Hepatology

Curcumin maintenance therapy for ulcerative colitis: Randomized, multicenter, double-blind, placebo-controlled trial

Hiroyuki Hanai et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Endocrinology & Metabolism

Safety and efficacy of NT, an herbal supplement, in treating human obesity

F. L. Greenway et al.

INTERNATIONAL JOURNAL OF OBESITY (2006)

Article Gastroenterology & Hepatology

Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis

Marcia Cruz-Correa et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Review Public, Environmental & Occupational Health

Uterine fibroids: A review of health-related quality of life assessment

Valerie S. L. Williams et al.

JOURNAL OF WOMENS HEALTH (2006)

Article Gastroenterology & Hepatology

Curcumin therapy in inflammatory bowel disease: A pilot study

PR Holt et al.

DIGESTIVE DISEASES AND SCIENCES (2005)

Review Multidisciplinary Sciences

The challenge of emerging and re-emerging infectious diseases

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NATURE (2004)

Article Integrative & Complementary Medicine

Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: A pilot study

R Bundy et al.

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2004)

Review Obstetrics & Gynecology

Health-related quality of life measurement in women with common benign gynecologic conditions: A systematic review

GL Jones et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2002)

Article Nutrition & Dietetics

Effect of different curcumin dosages on human gall bladder

A Rasyid et al.

ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION (2002)

Article Public, Environmental & Occupational Health

Autoimmune diseases: A leading cause of death among young and middle-aged women in the United States

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AMERICAN JOURNAL OF PUBLIC HEALTH (2000)