Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 90, Pages 16197-16200Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc06714f
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- Ministry of Science and Technology
- Ministry of Education, Taiwan (ROC)
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In this communication, we report a general strategy to create fluorescence switchable probes, where a small molecule ligand is conjugated to a fluorescent molecular rotor, for the selective detection of proteins through a non-enzymatic process. In the presence of target proteins, bond rotation of the molecular rotor is restricted, thereby triggering the emission of strong fluorescence.
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