Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 81, Pages 15023-15026Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc03581c
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Funding
- National Institutes of Health (NIH) [AI087968, EB006521, GM107986]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [K25AI087968] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB006521, R21EB018959] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R21GM107986] Funding Source: NIH RePORTER
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We observed over 400-fold enhanced fluorescence from single Cy5 molecules assembled on multilayer silver nanoparticle-dielectric-metal (PDM) substrate. This substantial enhancement is due to the near-field enhanced excitation, emission, and interaction of Cy5 with plasmonic nanostructures. Experimental observation is supported by finite-element method calculations.
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