Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 74, Pages 14099-14102Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05111h
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Funding
- Novartis
- Royal Society grant [RG140746]
- BBSRC grant [BB/L02229X/1]
- BBSRC [BB/L02229X/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/L02229X/1] Funding Source: researchfish
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i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used changes in pH to fold the DNA. Herein we describe how copper(II) cations can alter the conformation of i-motif DNA into an alternative hairpin structure which is reversible by chelation with EDTA.
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