Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 69, Issue -, Pages 27-36Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2016.06.062
Keywords
Polymer-matrix composites; Chitosan; 3D printing strips; Antibacterial activity; Cytocompatibility
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Funding
- Ministry of Science and Technology (Taipei City, Taiwan, R.O.C.) [MOST 104-2221-E-244-011]
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The mechanical properties, cytocompatibility, and fabrication of three-dimensional (3D) printing strips of composite materials containing polylactide (PLA) and chitosan (CS) were evaluated. Maleic anhydride-grafted polylactide (PLA-g-MA) and CS were used to enhance the desired characteristics of these composites. The PLA-g-MA/CS materials exhibited better mechanical properties than the PLA/CS composites; this effect was attributed to a greater compatibility between the grafted polyester and CS. The water resistance of the PLA-g-MA/CS composites was greater than that of the PLA/CS composites; cytocompatibility evaluation with human foreskin fibroblasts (FBs) indicated that both materials were nontoxic. Moreover, CS enhanced the antibacterial activity properties of PIA-g-MA and PLA/CS composites. (C) 2016 Elsevier B.V. All rights reserved.
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