Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 60, Issue -, Pages 92-99Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2015.11.011
Keywords
Antibacterial; Self-assemblies; RAFT dispersion polymerization; Silver; Nanoparticles; Nanocomposites
Categories
Funding
- Knowledge Innovation Program of Shenzhen City [JCYJ2130329104920949]
- Nature AMP
- Science Fund of Guangdong Province [2015A030310238]
- Startup Program in Science of Shenzhen University
Ask authors/readers for more resources
We report a simple route to prepare silver nanoparticle (Ag NP) loaded amine functionalized poly-oligomeric (ethylene glycol) methyl ether methacrylate block poly-glycidyl methacrylate (POEGMA-b-PGMA) vesicles as an effective antibacterial agent. Self-assemblies of POEGMA-b-PGMA were prepared from reversible addition fragmentation chain transfer (RAFT) dispersion polymerization mediated by a POEGMA macro-chain transfer agent (macro-CTA) in ethanol. Amine-functionalized self-assemblies were applied for Ag NP loading by using amine and hydroxyl groups as both the coordination agent and reductant under hydrothermal condition in high-pressure steam sterilization. 12.7 wt.% content of fine Ag NP well-dispersed in vesicles showed excellent antibacterial activities with the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) below 5.0 and 10.0 mg/L against Escherichia coli and 2.5 and 80 mg/L against Staphylococcus aureus respectively. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available