(2Z,5Z)-5-((3-(Benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one

The reaction of a 1:1 mixture of 3-(benzofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (1) and 2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one (2) in anhydrous ethanol containing piperidine as a catalyst under reflux for 4 h gave (2Z,5Z)-5-((3-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one (3), C34H24N4O3F, in 82% yield. The structure of the newly synthesized heterocycle was confirmed via X-ray diffraction and spectral analyses.

Automated summary

A 1:1 mixture of compound 1 and compound 2 reacted under reflux in anhydrous ethanol in the presence of piperidine as a catalyst for 4 hours, resulting in the formation of compound 3 with 82% yield. The structure of the newly synthesized heterocycle was confirmed using X-ray diffraction and spectral analyses.