Synthesis, Spectroscopic, and Thermal Analyses of 2-Oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate

The 2-oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate was synthesized in good yield using a triethylamine-mediated O-acylation reaction between 8-hydroxyquinolin-2(1H)-one and 4-chlorobenzoyl chloride in acetonitrile at room temperature. This methodology is notable for its clean reaction profile and straightforward procedure. The 2-oxoquinoline derivative was characterized using spectroscopic, spectrometric, and thermal analyses, enabling a comprehensive understanding of its molecular structure and thermal properties.

Automated summary

The 2-oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate was synthesized efficiently through an O-acylation reaction mediated by triethylamine between 8-hydroxyquinolin-2(1H)-one and 4-chlorobenzoyl chloride in acetonitrile at room temperature. This method offers a clean reaction pathway and a straightforward procedure. The synthesized 2-oxoquinoline derivative was characterized using spectroscopic, spectrometric, and thermal analyses for understanding its molecular structure and thermal properties comprehensively.