Journal
MATERIALS LETTERS
Volume 178, Issue -, Pages 239-242Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2016.05.011
Keywords
Nanoparticles; Green synthesis; Biomaterials; Biological activities
Funding
- DST, New Delhi [SERB-DST SB/S2/RJN-087/2014]
- CSIR, New Delhi
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An eco-friendly, very simple method for synthesis of gold-reduced graphene oxide (Au-rGO) nano composite was developed using fruit of Piper pedicellatum C.DC. Its characterization was done by UV-visible, FT-IR, XRD, XPS, Raman, SEM-EDX, TEM analysis. The antibacterial activity of Au-rGO nano particles was investigated against the Gram negative bacteria Pseudomonas aeruginosa, Klebsiella pneumoniae and Gram positive bacteria Staphylococcus aureus and Bacillus cereus. In addition, in-vitro cell based cytotoxicity study was performed for Au-rGO and GO against PC3 (aggressive human prostate carcinoma cell line) and RWPE-1(non-malignant human prostate epithelial cells). Cytotoxicity assay revealed that Au-rGO is more toxic than GO nanoparticles against PC3 cancer cells compared to RWPE-1. (C) 2016 Elsevier B.V. All rights reserved.
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