The Impact of Radiolabeled Nanomaterials

Review Chemistry, Multidisciplinary

Smart Nanomaterials in Cancer Theranostics: Challenges and Opportunities

Brijendra Kumar Kashyap et al.

Summary: Cancer, the second leading cause of death worldwide, requires improved targeting strategies to mitigate the toxicities of traditional therapies. Nanomaterials have shown promise in cancer theranostics, offering precise targeting and stability. The development of smart nanomaterials has revolutionized cancer diagnosis and treatment, allowing for encapsulation of multiple molecules and functionalization with various biosubstrates. This review highlights the advantages and challenges of utilizing smart nanomaterials in cancer theranostics and concludes that their use can significantly improve tumor detection and therapy.

ACS OMEGA (2023)

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Article Pharmacology & Pharmacy

[223Ra] RaCl2 nanomicelles showed potent effect against osteosarcoma: targeted alpha therapy in the nanotechnology era

Yang Yang et al.

Summary: Radium dichloride ([Ra-223] RaCl2) nanomicelles have shown superior therapeutic effects compared to pure radium dichloride ([Ra-223] RaCl2), validating the feasibility of nanotechnology in alpha-radiotherapy.

DRUG DELIVERY (2022)

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Article Polymer Science

Nanomicelles of Radium Dichloride [223Ra]RaCl2 Co-Loaded with Radioactive Gold [198Au]Au Nanoparticles for Targeted Alpha-Beta Radionuclide Therapy of Osteosarcoma

Barbara Nayane Rosario Fernandes Souza et al.

Summary: This study aims to analyze the antitumoral effects of [Ra-223]Ra nanomicelles co-loaded with radioactive gold nanoparticles ([Au-198]AuNPs) and explore the efficiency of combined alpha and beta radiation therapy.

POLYMERS (2022)

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Review Nanoscience & Nanotechnology

Inorganic Radiolabeled Nanomaterials in Cancer Therapy: A Review

Tom A. Lemaitre et al.

Summary: This review discusses the incorporation of therapeutic radionuclides into inorganic nanoconstructs as carriers for cancer treatment. Different types of nanomaterials and methods of incorporating radionuclides, and their impact on stability and in vitro and in vivo performances, are discussed.

ACS APPLIED NANO MATERIALS (2022)

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Review Chemistry, Medicinal

Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology

Martha Sahyli Ortega Pijeira et al.

Summary: Nanotechnology holds great promise for cancer detection, prevention, and treatment. Nanomedicine utilizes nanoparticles for imaging, diagnosis, drug delivery, and therapy, enabling more specific and personalized cancer treatment.

EJNMMI RADIOPHARMACY AND CHEMISTRY (2022)

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Article Robotics

Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder

Ana C. Hortelao et al.

Summary: Enzyme-powered nanomotors exhibit swarming behavior and have been successfully tracked using PET both in vitro and in vivo. This technology demonstrates enhanced fluid mixing and collective migration capabilities, marking a key advancement in the field of biomedical nanorobotics.

SCIENCE ROBOTICS (2021)

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Article Medicine, Legal

Regulatory landscape of nanotechnology and nanoplastics from a global perspective

Jacqueline Allan et al.

Summary: Nanotechnology offers novel solutions to societal challenges, but regulatory frameworks struggle to keep pace with its rapid development. Global collaboration and consensus are needed, particularly in emerging fields like micro- and nanoplastics.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2021)

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Review Biochemical Research Methods