Journal
JOURNAL OF COMPOSITES SCIENCE
Volume 7, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/jcs7060255
Keywords
photodynamic therapy; Radachlorin; nanoparticle-photosensitizer conjugates; flow cytometry
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A promising material for hybrid photodynamic therapy, consisting of Ce0.5Y0.35Tb0.15F3 crystalline nanoparticles and Radachlorin, is investigated. The conjugation of Ce0.5Y0.35Tb0.15F3 nanoparticles and Radachlorin using polyethylenimine (PEI) is tested and shows an energy transfer efficiency of 28%. The stable conjugates of CeF3-Tb3+ NPs and Radachlorin using PEI have a distance of approximately 5 nm between nanoparticles and photosensitizer molecules.
Promising material for hybrid photodynamic therapy consisting of Ce0.5Y0.35Tb0.15F3 crystalline nanoparticles and Radachlorin is reported. One possible option of conjugation of Ce0.5Y0.35Tb0.15F3 nanoparticles and Radachlorin using polyethylenimine (PEI) is tested. The energy transfer reaches 28%. It is shown that conjugates of CeF3-Tb3+ NPs and Radachlorin using PEI-are stable, and the distance between nanoparticles and photosensitizer molecules is about 5 nm.
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