Integrating tuberculosis and COVID-19 molecular testing in Lima, Peru: a cross-sectional, diagnostic accuracy study

Article Public, Environmental & Occupational Health

Considerations for simultaneous testing of COVID-19 and tuberculosis in high-burden countries

Morten Ruhwald et al.

Lancet Global Health (2022)

Article Pharmacology & Pharmacy

Impact of the COVID-19 Pandemic on the Diagnosis of Tuberculosis in Brazil: Is the WHO End TB Strategy at Risk?

Mariana do Rosario Souza et al.

Summary: The study revealed a decrease in TB and PTB diagnoses in Brazil following the outbreak of the COVID-19 pandemic, with 22 states showing a reduction in TB diagnoses. Additionally, there was a significant decrease in baciloscopy-positive (BP) cases.

FRONTIERS IN PHARMACOLOGY (2022)

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Article Immunology

Secondary Attack Rate, Transmission and Incubation Periods, and Serial Interval of SARS-CoV-2 Omicron Variant, Spain

Javier Del Aguila-Mejia et al.

Summary: Contact tracing data in Cantabria, Spain during December 2021 revealed that the SARS-CoV-2 Omicron variant had a higher transmission rate (39% secondary attack rate) compared to the Delta variant (26% secondary attack rate), regardless of vaccination status. The incubation and serial interval periods were also shorter. Half of the Omicron transmissions occurred before symptom onset in the index case-patient.

EMERGING INFECTIOUS DISEASES (2022)

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Review Medicine, General & Internal

Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2 A Systematic Review and Meta-analysis

Guillaume Butler-Laporte et al.

Summary: This study evaluated the diagnostic accuracy of saliva NAAT for COVID-19 and found that its accuracy is similar to that of nasopharyngeal swab NAAT, especially in ambulatory settings. This suggests the potential for saliva NAAT as an alternative to nasopharyngeal swabs and supports further research in this area.

JAMA INTERNAL MEDICINE (2021)

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Review Multidisciplinary Sciences

Active pulmonary tuberculosis and coronavirus disease 2019: A systematic review and meta-analysis

Ashutosh Nath Aggarwal et al.

Summary: Active pulmonary tuberculosis is relatively common among COVID-19 patients and increases the risk of severe COVID-19 and COVID-19-related mortality.

PLOS ONE (2021)

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Review Immunology

The Incubation Period Distribution of Coronavirus Disease 2019: A Systematic Review and Meta-analysis

Hualei Xin et al.

Summary: The study found that the pooled median estimates of the mean, median, and 95th percentile for the incubation period of COVID-19 are 6.3 days, 5.4 days, and 13.1 days respectively. The estimates were significantly shorter before the epidemic peak in China compared to after, and variances were noticed for different methodological approaches.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Microbiology

Sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT- PCR testing

Padmapriya Banada et al.

Summary: Non-invasive sample collection and viral sterilizing buffers are important for COVID-19 testing by RT-PCR. The study aimed to compare the diagnostic yield of different non-invasive samples using standard VTM and a sterilizing buffer eNAT. Results showed that saliva and eNAT buffer can enhance sensitive detection of COVID-19 using point-of-care GeneXpert instruments.

JOURNAL OF MEDICAL MICROBIOLOGY (2021)

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Article Microbiology