Journal
MAGNETIC RESONANCE IMAGING
Volume 34, Issue 6, Pages 832-838Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mri.2016.03.003
Keywords
Magnetic resonance imaging; Skeletal muscle; Echo planar magnetic resonance imaging; Motion correction; Distortion correction; Image pre-processing
Funding
- Natural Sciences and Engineering Research Council (NSERC)
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This paper examines two artifacts facing researchers who use gradient echo (GRE) echo planar imaging (EPI) for time series studies of skeletal muscles in limbs. The first is through-plane blood flow during the acquisition, causing a vessel motion artifact that inhibits proper motion correction of the data. The second is distortion of EPI images caused by B-0 field inhomogeneities. Though software tools are available for correcting these artifacts in brain EPI images, the tools do not perform well on muscle images. The severity of the two artifacts was described using image similarity measures, and the data was processed with both a conventional motion correction program and custom written tools. The conventional program did not perform well on the limb images, in fact significantly degrading image quality in some trials. Data is presented which proves that arterial pulsatile signal caused the impairment in motion correction. The new tools were shown to perform much better, achieving substantial motion correction and distortion correction of the muscle EPI images. (C) 2016 Elsevier Inc. All rights reserved.
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