Journal
MACROMOLECULAR MATERIALS AND ENGINEERING
Volume 301, Issue 11, Pages 1288-1294Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mame.201600285
Keywords
dopamine; electropolymerization; nanofiber; polypyrrole; titanium
Funding
- National Basic Research Program of China [2012CB619100]
- National Natural Science Foundation of China [51541201, 51372087, 51232002]
- Natural Science Foundation of Guangdong Province [2015A030313493]
- Guangdong Province [2014A030310218]
- Shenzhen for basic research [JCYJ20140617143643478]
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Dopamine is a molecule that facilitates biomineralization, and it is used to prepare electropolymerization-induced polydopamine (PDA). For the first time, dopamine is used for template-free electrochemical polymerization to form biocompatible polypyrrole (PPy) nanofiber coatings on bone implants. Dopamine monomers are electropolymerized to PDA chains affixed to biomedical titanium after the nanomicelles are tuned to self-assemble by triggering the potential, resulting in nanofiber formation. Dopamine serves as a dopant to induce the formation of conductive PPy nanofibers and as a promoter to accelerate biomineralization, cell proliferation, and adhesion.
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