Journal
BJPSYCH OPEN
Volume 9, Issue 2, Pages -Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjo.2023.25
Keywords
Trauma; post-traumatic stress disorder; imaging; dissociative disorders; childhood experience
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By transiently stimulating the sympathetic nervous system and/or the hypothalamic-pituitary-adrenal (HPA) axis, the stress response can be enhanced, aiding in the identification of targets for personalized interventions.
Symptom provocation paradigms have been successfully developed to identify the neural correlates associated with post-traumatic stress disorder (PTSD) symptoms, especially dissociative behaviours, but have critical limitations. Transiently stimulating the sympathetic nervous system and/or the hypothalamic-pituitary-adrenal (HPA) axis can enhance the stress response to symptom provocation and would help identify targets for personalised interventions.
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