4.6 Review

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Journal

LIFE-BASEL
Volume 13, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/life13020522

Keywords

monkeypox virus; emerging viruses; vaccination; pathogenicity; outbreak

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Monkeypox virus is a zoonotic double-stranded DNA virus that causes disease in humans and mammals. It is associated with the smallpox virus and has been reported in various regions of Africa and the Northern and western hemispheres. This review focuses on the taxonomic classification, clinical presentations, and pathogenicity of the monkeypox virus in humans, as well as different diagnostic methods used for virus detection.
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.

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