Hallux Partial Necrosis Associated with Antiphospholipid Syndrome: The Importance of Early Accurate Diagnosis

Article Medicine, General & Internal

Hemostatic Efficacy of Absorbable Gelatin Sponges for Surgical Nail Matrixectomy after Phenolization-A Blinded Randomized Controlled Trial

Antonio Cordoba-Fernandez et al.

Summary: This study demonstrates that hemostatic gelatin sponges are effective and safe for controlling minor postoperative bleeding associated with matrixectomy after segmental phenolization.

JOURNAL OF CLINICAL MEDICINE (2022)

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Review Medicine, General & Internal

Laboratory Diagnosis of Antiphospholipid Syndrome: Insights and Hindrances

Arne Vandevelde et al.

Summary: The diagnosis and risk stratification of antiphospholipid syndrome (APS) are complex and require various laboratory tests. Efforts to standardize and optimize these tests are ongoing to improve diagnostic accuracy and repeatability. There are challenges in laboratory testing, such as interference by anticoagulation therapy for LAC detection and high variability due to different reagents and detection techniques.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Hematology

Comparing the efficacy and safety of direct oral anticoagulants versus Vitamin K antagonists in patients with antiphospholipid syndrome: a systematic review and meta-analysis

Xiaoling Wu et al.

Summary: Thromboprophylaxis is crucial in treating APS, and VKAs remain the first-choice treatment for high-risk APS patients, while DOACs are more appropriate for low-risk APS patients. The use of Rivaroxaban is associated with an increased risk of recurrent thrombosis in APS patients.

BLOOD COAGULATION & FIBRINOLYSIS (2022)

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Review Immunology

Pregnancy outcome predictors in antiphospholipid syndrome: A systematic review and meta-analysis

Isabel Johanna Walter et al.

Summary: This study identified previous thrombosis, laboratory category I, triple positivity, and lupus anticoagulant positivity as the most important predictors of adverse pregnancy outcomes.

AUTOIMMUNITY REVIEWS (2021)

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Article Cardiac & Cardiovascular Systems

Case Report: An Unusual Case of Acute Lower Limb Ischemia as Precursor of the Asherson's Syndrome

Edoardo Pasqui et al.

Summary: A case of a 65-year-old woman with acute lower limb arterial ischemia, ultimately diagnosed with Asherson's Syndrome and complicated by severe heparin-induced thrombocytopenia, was reported in this study. Following high-dose medical management, the patient's clinical condition was stabilized.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

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Review Rheumatology