☆ 4.5 Review

Recent Advances in Small Molecular Fluorescence Probes for Fatty Liver Diseases

CHEMOSENSORS (2023)

Related references

Note: Only part of the references are listed.

Article Spectroscopy

A turn-on fluorescent probe based on ESIPT and AIEE mechanisms for the detection of butyrylcholinesterase activity in living cells and in non-alcoholic fatty liver of zebrafish

Xiangyu Pei et al.

Summary: This article introduces the design and synthesis of a fluorescent probe HBT-BChE for biological detection and imaging of BChE. The probe has low background interference and high sensitivity, able to distinguish BChE from AChE, and can be used to detect intracellular BChE activity and evaluate the efficacy of BChE inhibitors. In in vivo studies using zebrafish, HBT-BChE demonstrates the potential as a powerful tool for non-alcoholic fatty liver disease.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2023)

Add to Collection

Article Chemistry, Analytical

Fast Response Fluorescent Probe with a Large Stokes Shift for Thiophenol Detection in Water Samples and Cell Imaging

Jinjie You et al.

Journal of Analysis and Testing (2023)

Add to Collection

Article Gastroenterology & Hepatology

Compromised hepatic mitochondrial fatty acid oxidation and reduced markers of mitochondrial turnover in human NAFLD

Mary P. Moore et al.

Summary: Compromised hepatic FAO and mitochondrial turnover are intimately linked to increasing NAFLD severity in patients with obesity.

HEPATOLOGY (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Advances in Optical Imaging of Nonalcoholic Fatty Liver Disease

Yang Shen et al.

Summary: Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can progress to liver fibrosis and hepatic carcinoma if not treated in time. Currently, the gold standard for clinical diagnosis of NAFLD, liver biopsy, is not widely accepted due to its invasiveness. Other non-invasive methods, such as magnetic resonance imaging and ultrasound, still suffer from low resolution and sensitivity. Optical imaging methods, including fluorescence imaging, photoacoustic imaging, and bioluminescence imaging, have been favored in recent years for their high spatiotemporal resolution and sensitivity. In this review, existing non-invasive optical imaging probes for the detection of biomarkers in NAFLD are summarized, and their design strategies and applications are discussed.

CHEMISTRY-AN ASIAN JOURNAL (2022)

Add to Collection

Article Medicine, Research & Experimental

Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription

Dongfang Wang et al.

Summary: Butyrylcholinesterase (BChE) regulates the levels of LDL receptor (LDLR) and LDL uptake capacity through the MEK-ERK signaling cascades, promoting cholesterol metabolism. PRMT5 is a regulator of LDL uptake and a substrate of BChE. Silencing BChE specifically in hepatocytes reduces plasma cholesterol levels, providing an effective therapeutic strategy for hypercholesterolemia.

LIFE SCIENCES (2022)

Add to Collection

Review Chemistry, Analytical

Recent Progress in Fluorescent Formaldehyde Detection Using Small Molecule Probes

Jiao-Jiao Zheng et al.

Summary: This review provides a comprehensive summary of recent research on fluorescent analysis of formaldehyde using small molecule probes. It discusses the sensing mechanisms, detection methods, and performance in various environments, as well as the challenges and future trends in formaldehyde detection based on fluorescent probes.

JOURNAL OF ANALYSIS AND TESTING (2022)

Add to Collection

Article Chemistry, Analytical

Measuring the pH of Acidic Vesicles in Live Cells with an Optimized Fluorescence Lifetime Imaging Probe

Kinuko Koda et al.

Summary: In this study, a new fluorescence probe, m-DiMeNAF488, was developed for measuring the acidic pH inside vesicles in living cells using fluorescence lifetime imaging microscopy (FLIM). The probe exhibits a pH-dependent equilibrium and distinct fluorescence lifetimes, allowing for the evaluation of pH changes in acidic vesicles. By using FLIM and m-DiMeNAF488, we were able to monitor the pH changes in phagosomes during phagocytosis.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Biophysics

Polarity-sensitive and lipid droplet-specific red emission fluorophore for identifying fatty liver of living mice through in vivo imaging

Lei Hu et al.

Summary: In this study, a red emission fluorophore probe LD-HW with high fluorescence quantum yield and selective recognition of lipid droplet polarity variation was successfully constructed. It could rapidly light up lipid droplets and monitor their dynamic behavior in real-time through a wash-free procedure. The probe showed great potential in non-invasive diagnosis of fatty liver.

BIOSENSORS & BIOELECTRONICS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Precision Navigation of Hepatic Ischemia-Reperfusion Injury Guided by Lysosomal Viscosity-Activatable NIR-II Fluorescence

Jihong Liu et al.

Summary: This study developed a new fluorescent probe (NP-V) that can detect lysosomal viscosity in hepatocytes and mice during HIRI, and achieved precise resection of the lesion area. It has significant implications in early warning and treatment planning for HIRI.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Add to Collection

Review Pharmacology & Pharmacy

Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer

Ning Li et al.

Summary: This review discusses the correlation between biomechanical cues and liver diseases from the viewpoint of mechanobiology. At the cellular level, changes in mechanical microenvironment induce phenotypic and functional alterations of hepatic cells, promoting liver fibrogenesis and hepatocarcinogenesis. At the molecular level, mechanical forces are sensed and transmitted into hepatic cells, activating various mechanotransduction pathways and regulating cell function.

ADVANCED DRUG DELIVERY REVIEWS (2022)

Add to Collection

Article Chemistry, Analytical

Solvatochromic Two-Photon Fluorescent Probe Enables In Situ Lipid Droplet Multidynamics Tracking for Nonalcoholic Fatty Liver and Inflammation Diagnoses

Houshi Huang et al.

Summary: In this study, a lipid droplet-specific fluorescence probe was successfully constructed, showing high quantum yield and excellent photostability. By utilizing two-photon fluorescence imaging, the probe enables real-time monitoring of lipid droplet dynamics and diagnosis of diseases in living mice.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Chemistry, Analytical

Bichromatic Imaging with Hemicyanine Fluorophores Enables Simultaneous Visualization of Non-alcoholic Fatty Liver Disease and Metastatic Intestinal Cancer

Weijia Xu et al.

Summary: In this study, a bichromatic fluorophore called Cy-914 was developed for the simultaneous diagnosis of NAFLD and metastatic intestinal cancer. Cy-914 showed different fluorescence signals at different wavelengths under acidic and neutral to slightly basic viscous conditions, and could monitor the progression of NAFLD. By visualizing different diseases in independent channels, this fluorophore improved fluorescence-guided surgery.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Chemistry, Analytical

Quantification of lipid droplets polarity for evaluating non-alcoholic fatty liver disease via fluorescence lifetime imaging

Chaofeng Lai et al.

Summary: The polarity of lipid droplets (LDs) is closely associated with the initiation and development of NAFLD. However, the lack of robust tools for quantitative diagnosis presents a challenge. In this study, a new polarity-sensitive probe CCB was synthesized, enabling real-time quantification of fatty liver degeneration through fluorescence lifetime imaging microscopy (FLIM). The probe's fluorescence lifetime showed a good linear fitting relationship with polarity, providing a means for quantitative detection of LDs' polarity. The robust probe CCB successfully monitored changes in LDs' polarity at cellular and tissue levels during the steatosis process of NAFLD, offering potential insights into quantitative diagnosis of NAFLD.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Recent research progress in galactose-based fluorescent probes for detection of biomarkers of liver diseases

Xiaojing Deng et al.

Summary: The liver, an important organ in the human body, is involved in various functions such as detoxification, metabolism, immunity, and digestion. Liver injury causes changes in biomarkers, small molecules, and enzymes, which can be detected using fluorescent probes to aid in the early diagnosis of liver diseases.

CHEMICAL COMMUNICATIONS (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Recent advances in small-molecule fluorescent probes for studying ferroptosis

Ya-Lin Qi et al.

Summary: Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death involved in the development and progression of various diseases. Small-molecule fluorescent probes have been used to study ferroptosis by tracking biomolecules or microenvironment-related parameters in vitro and in vivo.

CHEMICAL SOCIETY REVIEWS (2022)

Add to Collection

Article Materials Science, Biomaterials

Ratiometric imaging of butyrylcholinesterase activity in mice with nonalcoholic fatty liver using an AIE-based fluorescent probe

Chunbai Xiang et al.

Summary: In this study, we developed a novel fluorescent probe, TB-BChE, with aggregation-induced emission (AIE) characteristics for ratiometric imaging of BChE. TB-BChE demonstrated excellent sensitivity and specificity, and successfully achieved ratiometric imaging of BChE in a nonalcoholic fatty liver disease model.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Bright and Stable NIR-II J-Aggregated AIE Dibodipy-Based Fluorescent Probe for Dynamic In Vivo Bioimaging

Qisong Zhang et al.

Summary: An organic dye emitting in the second near-infrared window with enhanced fluorescence intensity was developed for in vivo bioimaging and biosensing applications, enabling high frame rate imaging.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Analytical

Highly Selective Fluorescent Probe Design for Visualizing Hepatic Hydrogen Sulfide in the Pathological Progression of Nonalcoholic Fatty Liver

Wei Li et al.

Summary: A highly selective near-infrared fluorescent probe was developed using molecular probe design and nanofunctionalization techniques, allowing for real-time monitoring of hepatic H2S levels during NAFLD progression.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Small Molecular Fluorescent Probes for Imaging of Viscosity in Living Biosystems

Haibin Xiao et al.

Summary: Viscosity, as a crucial microenvironment parameter, is closely connected to various cellular processes and diseases. The visualization of viscosity has gained increasing interest in recent years, leading to the development of new fluorescence probes for mapping viscosity inside living organisms. This review comprehensively summarizes viscosity-sensitive small molecular fluorescent probes used in bioimaging, with a focus on the past three years, while also discussing the current challenges and opportunities for developing viscosity-specific fluorescent probes.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

Add to Collection

Review Chemistry, Inorganic & Nuclear

Ratiometric two-photon fluorescence probes for sensing, imaging and biomedicine applications at living cell and small animal levels

Hui Jin et al.

Summary: This review summarizes recent advances in RTPF probes and their potential applications, focusing on design, principles, targets, samples, sensing mechanisms, bioimaging, and biomedical applications. It also discusses current states, challenges, and future perspectives in various aspects of RTPF probes for potential clinical therapy in malignant diseases and cancers.

COORDINATION CHEMISTRY REVIEWS (2021)

Add to Collection

Review Cell Biology

The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD

Ting Hong et al.

Summary: The overproduction of ROS and oxidative stress play crucial roles in the pathogenesis of acute and chronic liver diseases. NAFLD is characterized as a redox-centered disease, and dysregulation of nuclear receptors (NRs) may be key in regulating this process. Targeting NRs could be a promising strategy for improving oxidation damage and treating NAFLD.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Add to Collection

Review Neurosciences

Advanced imaging and labelling methods to decipher brain cell organization and function

Daniel Choquet et al.

Summary: The brain is a highly complex organ, and advancements in imaging methods and molecular tools have revolutionized our understanding of its structure and function. By combining the latest molecular tools with imaging techniques, researchers are able to investigate neural function at a greater resolution than previously possible.

NATURE REVIEWS NEUROSCIENCE (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Fluorescent Determination of Butyrylcholinesterase Activity and Its Application in Biological Imaging and Pesticide Residue Detection

Qian Zhang et al.

Summary: A background-free detection strategy for BChE with high sensitivity and selectivity was developed in this study, showing promising prospects for disease diagnosis.

ACS SENSORS (2021)

Add to Collection

Article Chemistry, Analytical

Dual-Stimulus Responsive Near-Infrared Reversible Ratiometric Fluorescent and Photoacoustic Probe for In Vivo Tumor Imaging

Xiao Liu et al.

Summary: A new dual-stimulus responsive near-infrared reversible ATP-pH probe has been developed for fluorescence and photoacoustic ratiometric imaging of tumors, effectively reducing cumulative response after intravenous injection and suitable for in vivo imaging.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Visualization of endoplasmic reticulum viscosity in the liver of mice with nonalcoholic fatty liver disease by a near-infrared fluorescence probe

Yongqing Zhou et al.

Summary: Nonalcoholic fatty liver disease (NAFLD) can cause serious liver damage, and early diagnosis and treatment of NAFLD can greatly improve treatment success rates. A new near-infrared (NIR) fluorescence imaging probe, Er-V, successfully monitored increased viscosity in the livers of mice with NAFLD, offering a new approach for early detection and diagnosis of NAFLD.

CHINESE CHEMICAL LETTERS (2021)

Add to Collection

Letter Acoustics

Ultrasound imaging for bladder hernia: a rare cause of female inguinal hernia

Ke-Vin Chang et al.

MEDICAL ULTRASONOGRAPHY (2021)

Add to Collection

Article Chemistry, Analytical

Exploring the Changes of Peroxisomal Polarity in the Liver of Mice with Nonalcoholic Fatty Liver Disease

Yongqing Zhou et al.

Summary: This study confirmed the crucial role of PPAR-a in the development of NAFLD, developed a new two-photon fluorescence imaging probe PX-P, and observed a significant decrease in peroxisomal polarity in the liver of NAFLD mice for the first time. Research findings revealed that the activity of PPAR-a was significantly influenced by excessive ONOO- and H2O2, which accelerated the occurrence of NAFLD.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Chemistry, Analytical

Lipid Droplet-Specific Fluorescent Probe for In Vivo Visualization of Polarity in Fatty Liver, Inflammation, and Cancer Models

Li Fan et al.

Summary: The research team synthesized a sensitive LD-TTP fluorescent probe that can efficiently detect and monitor changes in lipid droplet polarity, holding great potential for clinical diagnosis of lipid droplet polarity-related diseases.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Spectroscopy

Development of a one-step synthesized red emission fluorescent probe for sensitive detection of viscosity in vitro and in vivo

Jie Cheng et al.

Summary: Fluorescence imaging is an effective method for detecting biological parameters, and the NBI-V probe has good stability and high selectivity, making it suitable for detecting changes in viscosity both in vivo and in vitro.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Small molecule based fluorescent chemosensors for imaging the microenvironment within specific cellular regions

Junling Yin et al.

Summary: The microenvironment within specific organelles plays a vital role in cellular processes and physiological functions. Monitoring and understanding the variations in the microenvironment is essential for identifying disease development. Progress has been made in developing fluorescent probes to study the microenvironment within specific cellular regions, but comprehensive research on small-molecule fluorescent chemosensors for cellular microenvironments is still needed.

CHEMICAL SOCIETY REVIEWS (2021)

Add to Collection

Article Materials Science, Biomaterials

Turn-on fluorescent probe for lipid droplet specific imaging of fatty liver and atherosclerosis

Shufen Li et al.

Summary: A novel NIR fluorescent probe TNBD was synthesized with low emission in aqueous solution and solid state, but enhanced emission in oleic acid. It exhibited impressive LD specific fluorescence turn-on ability in cells and disease samples, providing a new way to prepare a NIR LD targeted fluorescence probe.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Near-infrared fluorescent molecular probes for imaging and diagnosis of nephro-urological diseases

Jiaguo Huang et al.

Summary: Near-infrared (NIR) fluorescence imaging shows great potential in both basic biomedical research and clinical practice, especially in the diagnosis of nephron-urological diseases. The development of molecular probes has improved detection specificity and contrast enhancement in imaging.

CHEMICAL SCIENCE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Structural and process controls of AIEgens for NIR-II theranostics

Shunjie Liu et al.

Summary: Aggregation-induced emission (AIE) is a cutting-edge technology for developing highly efficient NIR-II emitters and photothermal agents, with the optimization of multi-hierarchical structures and intramolecular motions balancing fluorescence imaging and photothermal therapy functions.

CHEMICAL SCIENCE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease

Liqian Gao et al.

Summary: Parkinson's disease is a neurodegenerative disease with complex pathological processes and remains difficult to treat. Developing new tools for early diagnosis and treatment, including the use of fluorescent probes to monitor pathological features, is crucial.

CHEMICAL SOCIETY REVIEWS (2021)

Add to Collection

Article Chemistry, Analytical

Visualization of Lipid Droplets in Living Cells and Fatty Livers of Mice Based on the Fluorescence of π-Extended Coumarin Using Fluorescence Lifetime Imaging Microscopy

Toshitada Yoshihara et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection

Review Biochemistry & Molecular Biology

The Molecular and Mechanistic Insights Based on Gut-Liver Axis: Nutritional Target for Non-Alcoholic Fatty Liver Disease (NAFLD) Improvement

Yun Ji et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Real-Time Imaging and Simultaneous Quantification of Mitochondrial H2O2 and ATP in Neurons with a Single Two-Photon Fluorescence-Lifetime-Based Probe

Zhou Wu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Article Chemistry, Analytical

High-Selectivity Fluorescent Reporter toward Peroxynitrite in a Coexisting Nonalcoholic Fatty Liver and Drug-Induced Liver Diseases Model

Dan Cheng et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection

Review Cell Biology

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

Anne Fougerat et al.

CELLS (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Activatable Off-on Near-Infrared QCy7-based Fluorogenic Probes for Bioimaging

Xueqian Chen et al.

CHEMISTRY-AN ASIAN JOURNAL (2020)

Add to Collection

Article Allergy

Regulating metabolic inflammation by nutritional modulation

Hugo Charles-Messance et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Review Cell Biology

Role of Oxidative Stress in Hepatic and Extrahepatic Dysfunctions during Nonalcoholic Fatty Liver Disease (NAFLD)

Andrea Gonzalez et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

Add to Collection

Article Cell Biology

Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome

Oren Rom et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

In situ visualization of peroxisomal viscosity in the liver of mice with non-alcoholic fatty liver disease by near-infrared fluorescence and photoacoustic imaging

Yongqing Zhou et al.

CHEMICAL SCIENCE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging

Junjie Chen et al.

CHEMICAL COMMUNICATIONS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Engineering a highly selective probe for ratiometric imaging of H2Snand revealing its signaling pathway in fatty liver disease

Wei Li et al.

CHEMICAL SCIENCE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Tri-functional platform for construction of modular antibody fragments for in vivo18F-PET or NIRF molecular imaging

Raymond F. Gamache et al.

CHEMICAL SCIENCE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells

Shohei Uchinomiya et al.

CHEMICAL COMMUNICATIONS (2020)

Add to Collection

Article Chemistry, Analytical

Visualization of Mitochondrial Viscosity in Inflammation, Fatty Liver, and Cancer Living Mice by a Robust Fluorescent Probe

Junling Yin et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection

Review Chemistry, Multidisciplinary

Coumarin-Based Small-Molecule Fluorescent Chemosensors

Duxia Cao et al.

CHEMICAL REVIEWS (2019)

Add to Collection

Article Chemistry, Applied

Novel fluorophores based on imidazopyrazine derivatives: Synthesis and photophysical characterization focusing on solvatochromism and sensitivity towards nitroaromatic compounds

Egor V. Verbitskiy et al.

DYES AND PIGMENTS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Ultrathin Tellurium Oxide/Ammonium Tungsten Bronze Nanoribbon for Multimodality Imaging and Second Near-Infrared Region Photothermal Therapy

Yaru Cheng et al.

NANO LETTERS (2019)

Add to Collection

Article Materials Science, Biomaterials

Identification of fatty liver disease at diverse stages using two-photon absorption of triphenylamine-based BODIPY analogues

Tao Shao et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

Add to Collection

Article Chemistry, Analytical

Phasor-Fluorescence Lifetime Imaging Microscopy Analysis to Monitor Intercellular Drug Release from a pH-Sensitive Polymeric Nanocarrier

Ting Zhou et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection

Review Medicine, General & Internal

Nonalcoholic steatohepatitis in posttransplantation liver: Review article

Antonio Ricardo Cardia Ferraz de Andrade et al.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA (2018)

Add to Collection

Review Nutrition & Dietetics

Mechanisms by Which Dietary Fatty Acids Regulate Mitochondrial Structure-Function in Health and Disease

E. Madison Sullivan et al.

ADVANCES IN NUTRITION (2018)

Add to Collection

Review Acoustics

LIVER ULTRASOUND ELASTOGRAPHY: AN UPDATE TO THE WORLD FEDERATION FOR ULTRASOUND IN MEDICINE AND BIOLOGY GUIDELINES AND RECOMMENDATIONS

Giovanna Ferraioli et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Lipid Droplets in Health and Disease

Gizem Onal et al.

LIPIDS IN HEALTH AND DISEASE (2017)

Add to Collection

Article Gastroenterology & Hepatology

Histology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Adults and Children

David E. Kleiner et al.

CLINICS IN LIVER DISEASE (2016)

Add to Collection

Review Gastroenterology & Hepatology

Critical comparison of elastography methods to assess chronic liver disease

Mireen Friedrich-Rust et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors

K. David Wegner et al.

CHEMICAL SOCIETY REVIEWS (2015)

Add to Collection

Article Gastroenterology & Hepatology

Challenges and Opportunities in Drug and Biomarker Development for Nonalcoholic Steatohepatitis: Findings and Recommendations From an American Association for the Study of Liver Diseases-US Food and Drug Administration Joint Workshop

Arun J. Sanyal et al.

HEPATOLOGY (2015)

Add to Collection

Editorial Material Multidisciplinary Sciences

Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease

Weiwei Jiang et al.

SCIENTIFIC REPORTS (2015)

Add to Collection

Review Chemistry, Multidisciplinary

Near-infrared light-responsive nanomaterials in cancer therapeutics

Vijayakumar Shanmugam et al.

CHEMICAL SOCIETY REVIEWS (2014)

Add to Collection

Article Gastroenterology & Hepatology

Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats

Zhu-Lin Luo et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014)

Add to Collection

Editorial Material Gastroenterology & Hepatology

Nuclear Control of Inflammation and Fibrosis in Nonalcoholic Steatohepatitis: Therapeutic Potential of Dual Peroxisome Proliferator-Activated Receptor Alpha/Delta Agonism

Pablo Quintero et al.

HEPATOLOGY (2013)

Add to Collection

Review Physiology

Small-molecule fluorophores and fluorescent probes for bioimaging

Takuya Terai et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2013)

Add to Collection

Review Gastroenterology & Hepatology

What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?

Giovanni Tarantino et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

Add to Collection

Article Gastroenterology & Hepatology

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

Bharath Nath et al.

HEPATOLOGY (2012)

Add to Collection

Review Chemistry, Multidisciplinary

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Xiaoqiang Chen et al.

CHEMICAL SOCIETY REVIEWS (2011)

Add to Collection

Article Gastroenterology & Hepatology

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

DE Kleiner et al.

HEPATOLOGY (2005)

Add to Collection

Article Medicine, Research & Experimental

Cellular mechanisms of insulin resistance

GI Shulman

JOURNAL OF CLINICAL INVESTIGATION (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.