Covalent Organic Frameworks-Based Electrochemical Sensors for Food Safety Analysis

Food safety is a key issue in promoting human health and sustaining life. Food analysis is essential to prevent food components or contaminants causing foodborne-related illnesses to consumers. Electrochemical sensors have become a desirable method for food safety analysis due to their simple, accurate and rapid response. The low sensitivity and poor selectivity of electrochemical sensors working in complex food sample matrices can be overcome by coupling them with covalent organic frameworks (COFs). COFs are a kind of novel porous organic polymer formed by light elements, such as C, H, N and B, via covalent bonds. This review focuses on the recent progress in COF-based electrochemical sensors for food safety analysis. Firstly, the synthesis methods of COFs are summarized. Then, a discussion of the strategies is given to improve the electrochemistry performance of COFs. There follows a summary of the recently developed COF-based electrochemical sensors for the determination of food contaminants, including bisphenols, antibiotics, pesticides, heavy metal ions, fungal toxin and bacterium. Finally, the challenges and the future directions in this field are discussed.

Automated summary

Food safety is crucial for promoting human health and sustaining life. Electrochemical sensors coupled with covalent organic frameworks (COFs) have emerged as a desirable method for analyzing food contaminants. This review summarizes the synthesis methods of COFs, discusses strategies to enhance their electrochemical performance, and provides an overview of recent advancements in COF-based electrochemical sensors for detecting food contaminants. Challenges and future directions in this field are also discussed.