The Employment of the Surface Plasmon Resonance (SPR) Microscopy Sensor for the Detection of Individual Extracellular Vesicles and Non-Biological Nanoparticles

Article Chemistry, Multidisciplinary

Metal-Dielectric Interfacial Engineering with Mesoporous Nano- Carbon Florets for 1000-Fold Fluorescence Enhancements: Smartphone-Enabled Visual Detection of Perindopril Erbumine at a Single-molecular Level

Seemesh Bhaskar et al.

Summary: Introduces a carbon florets structure as a non-plasmonic dielectric interface, which enhances light entrapment and achieves plasmon-free generation of electromagnetic hotspots.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2023)

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Review Chemistry, Analytical

Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission

Seemesh Bhaskar

Summary: In the past decade, novel nano-engineering protocols combined with fluorescence spectroscopic techniques have improved the intensity of radiating dipoles through plasmon-enhanced fluorescence (PEF). This has led to a significant improvement in the detection limit of analytes of interest due to the higher sensitivity of augmented fluorescence signals. The integration of metallic thin films sustaining surface plasmon polaritons (SPPs) with PEF platforms has resulted in surface plasmon-coupled emission (SPCE), which has greatly enhanced the global collection efficiency.

MICROMACHINES (2023)

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Review Chemistry, Analytical

A review of optical methods for ultrasensitive detection and characterization of nanoparticles in liquid media with a focus on the wide field surface plasmon microscopy

Shavkat Nizamov et al.

Summary: The development of nanotechnology has posed new challenges to analytical science, specifically in the ultrasensitive detection and characterization of nanoparticles in complex media. This review focuses on analyzing various approaches and physical principles, with particular emphasis on optical methods. The detection and analysis of nanoparticles in volume and on surfaces are discussed, highlighting the intensive development of surface sensing technologies. The wide-field surface plasmon resonance microscopy is highlighted as a novel and effective tool for ultrasensitive detection and chemical identification of individual nanoparticles.

ANALYTICA CHIMICA ACTA (2022)

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Article Imaging Science & Photographic Technology

A Data-Centric Augmentation Approach for Disturbed Sensor Image Segmentation

Andreas Roth et al.

Summary: In the context of sensor-based data analysis, compensating for image artifacts poses a challenge, particularly when structures of interest are not clearly visible. Deep learning approaches have shown success, but rely heavily on the availability of labeled data. This study introduces a data-centric augmentation method using generative adversarial networks to enhance labeled data with synthetic artifacts, leading to improved segmentation results and a 22% increase in F1-score for a detection problem.

JOURNAL OF IMAGING (2021)

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Editorial Material Chemistry, Analytical