☆ 4.7 Article

Hybridization Chain Reaction-Based Electrochemical Biosensors by Integrating the Advantages of Homogeneous Reaction and Heterogeneous Detection

BIOSENSORS-BASEL (2023)

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Surface-tethered electrochemical biosensor for telomerase detection by integration of homogeneous extension and hybridization reactions

Lin Liu et al.

Summary: A sensitive electrochemical biosensor for telomerase detection was developed by integrating homogeneous extension and hybridization reactions and surface-tethered detection. The biosensor exhibited strong electrochemical signals from the oxidation of Fc tags when the bio-DNA/DNA/Fc-AuNP hybrids were tethered to streptavidin-modified electrodes through specific avidin-biotin interactions. This method has great potential in clinical diagnosis and anti-cancer drug development.

TALANTA (2023)

Add to Collection
Article Chemistry, Analytical

Y-shaped walker with abundant recognition domians mediated ultrasensitive electrochemical biosensor for miRNA-21 detection

Liang Zhu et al.

Summary: In this study, an ultrasensitive electrochemical biosensor was constructed using a high-efficiency Y-shaped DNA walker with abundant recognition domains. The Y-shaped DNA walker could be synthesized through rolling circle amplification with the assistance of padlock, and it showed significantly higher cleavage efficiency compared to conventional Y-shaped walkers. The biosensor achieved ultrasensitive detection of miRNA-21 with a detection limit of 10.6 aM, indicating its potential for sensitive detection of biomarkers and early diagnosis of diseases.

SENSORS AND ACTUATORS B-CHEMICAL (2023)

Add to Collection
Article Chemistry, Analytical

Self-Powered Biosensor for a Highly Efficient and Ultrasensitive Dual-Biomarker Assay

Futing Wang et al.

Summary: A dual-biomarker, self-powered biosensor was developed using enzymatic biofuel cells, catalytic hairpin assembly, and DNA hybridization chain reaction. It can detect microRNA-21 (miRNA-21) and microRNA-155 (miRNA-155) with high sensitivity. The biosensor operates by generating a double-helix chain in the presence of miRNA-21, while miRNA-155 inhibits the completion of the reaction. The self-powered biosensor allows for simultaneous ultrasensitive detection of miRNA-21 and miRNA-155, with detection limits of 0.15 and 0.66 fM, respectively. It also demonstrates highly sensitive detection in human serum samples.

ANALYTICAL CHEMISTRY (2023)

Add to Collection
Article Chemistry, Analytical

Ratiometrically homogeneous electrochemical biosensor based on the signal amplified strategy of dual DNA nanomachines for microRNA analysis

Yan Guan et al.

Summary: In this study, a dual DNA nanomachines-based homogeneous electrochemical biosensor was developed for the sensitive detection of miRNA. Co-based metal organic frameworks (Co-MOFs) and toluidine blue (TB) were used as signal probes and internal reference probes, respectively. The introduction of internal reference probes improved the stability of the detection procedure. Additionally, magnetic separation technique simplified the development of immobilization-free electrochemical miRNA biosensors. With this biosensor, the highly sensitive and selective detection of miRNA-141 was achieved in a wide concentration range, providing new opportunities for the diagnosis of miRNA-related diseases.

TALANTA (2023)

Add to Collection
Review Electrochemistry

Application of Hybridization Chain Reaction (HCR) in Electrochemical Analysis

Qiongyu Zhang

Summary: This review highlights the progress of HCR-based electrochemical biosensors in different types of signal reporters, which have advantages of simplicity, enzyme-free, and isothermal amplification.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2022)

Add to Collection
Article Chemistry, Analytical

Sandwich-type microRNA biosensor based on graphene oxide incorporated 3D-flower-like MoS2 and AuNPs coupling with HRP enzyme signal amplification

Jiangbo Dong et al.

Summary: A sandwich electrochemical biosensing strategy using graphene oxide incorporated MoS2 nanocomposites and gold nanoparticles was developed for ultrasensitive detection of miRNA-21. The biosensor showed high sensitivity and selectivity, with a low detection limit. It has great potential for clinical analysis and disease diagnosis.

MICROCHIMICA ACTA (2022)

Add to Collection
Review Chemistry, Analytical

Advances in Design Strategies of Multiplex Electrochemical Aptasensors

Iwona Grabowska et al.

Summary: In recent years, the development of biosensor technology has been accelerated by the increasing demand for simple, fast, and cost-effective detection of food and environmental contaminants, as well as the need for monitoring biomarkers of different diseases. However, simultaneous determination of multiple analytes in a single measurement using biosensors is still a major challenge. Electrochemical aptasensors, combining the high sensitivity and scalability of electrochemical detection systems with the specificity of aptamers, are considered highly effective devices for simultaneous detection of multiple-target analytes. This review focuses on multi-label approaches based on metal quantum dots and ions, redox labels, and enzyme labels, and highlights the use of different nanomaterials in the construction of these aptasensors. The review also discusses the recent applications of multiplexed detection platforms in clinical diagnostics, food control, and environmental monitoring, and addresses the advantages, disadvantages, challenges, and prospects of the developed aptasensors.

SENSORS (2022)

Add to Collection
Article Chemistry, Analytical

Heterogeneous sensing of post-translational modification enzymes by integrating the advantage of homogeneous analysis

Ning Xia et al.

Summary: The study introduces a novel sensing platform utilizing avidin-modified interface and biotin-labeled substrates as probes for heterogeneous analysis, combining the advantages of homogeneous and heterogeneous assays while overcoming their limitations.

TALANTA (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Electrochemical Biosensors Employing Hybridization Chain Reaction: From Structural Design to Applications

Hongxing Li et al.

Summary: Electrochemical biosensors are emerging sensor technologies that use amplification strategies to achieve ultrasensitivity for specific analytes. Hybridization chain reaction (HCR) is a cost-effective and enzyme-free amplification strategy that has been coupled with electrochemistry to enhance the sensitivity of biosensors. This review summarizes the significant achievements of HCR-amplified electrochemical biosensors in the past decade, including their design, challenges, and opportunities.

ADVANCED MATERIALS INTERFACES (2022)

Add to Collection
Review Electrochemistry

Recent Advancement in the development of hybridization chain reaction-based electrochemiluminescence biosensors

Ting Sun et al.

Summary: Electrochemiluminescence (ECL) biosensors are widely used in bioassays due to their high sensitivity, fast response, simple equipment, and low cost. Signal amplification is an important strategy to improve the sensitivity of ECL biosensors, and common enhancement strategies include DNA amplification, enzyme-assisted signal enhancement, nanomaterials-based amplification, and the application of redox-active probes and luminophores. Among them, hybridization chain reaction (HCR) offers simple experimental operation and high amplification efficiency, making it suitable for integrating with various detection technologies for signal enhancement.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2022)

Add to Collection
Review Electrochemistry

Progress in Hybridization Chain Reaction-Based Photoelectrochemical Biosensors

Yunxiao Feng et al.

Summary: This article addresses the progress in the development of photoelectrochemistry (PEC) biosensors in combination with the Hybridization Chain Reaction (HCR)-based signal amplification.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2022)

Add to Collection
Review Chemistry, Analytical

Advances in nucleic acids-scaffolded electrical sensing of extracellular vesicle biomarkers

Ting-Ting Liang et al.

Summary: This review summarizes the recent advances in nucleic acids-mediated extracellular vesicles (EVs) detection, with a focus on electrochemical strategies. It highlights the contribution of nucleic acids, particularly DNA self-assembly structures, in analyzing EVs with high sensitivity. Furthermore, it discusses the challenges and future perspectives of electric EVs detection strategies in clinical applications.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2022)

Add to Collection
Article Chemistry, Analytical

DNA self-assembled FeNxC nanocatalytic network for ultrasensitive electrochemical detection of microRNA

Yunyun Ning et al.

Summary: In this study, a highly sensitive and specific electrochemical strategy was proposed for accurate detection of miRNA-21. The strategy utilized DSN-assisted target recycling and DNA self-assembled FeNxC nanocatalytic network, and achieved ultrasensitive detection of miRNA-21.

ANALYTICA CHIMICA ACTA (2022)

Add to Collection
Review Chemistry, Inorganic & Nuclear

Application of electrochemical biosensors for the detection of microRNAs (miRNAs) related to cancer

Masoud Negahdary et al.

Summary: Molecular diagnoses, especially using miRNAs as cancer biomarkers, have shown great potential in cancer diagnosis and prognosis. Electrochemical biosensors have been widely researched for their ability to detect miRNAs, and nanomaterials have played an important role in optimizing the performance of these biosensors. This review provides an overview of the latest research on electrochemical biosensing of miRNAs, including the use of nanomaterials, different types of miRNAs, diagnostic techniques, and signal transducers.

COORDINATION CHEMISTRY REVIEWS (2022)

Add to Collection
Article Chemistry, Analytical

Target Recognition- and HCR Amplification-Induced In Situ Electrochemical Signal Probe Synthesis Strategy for Trace ctDNA Analysis

Aiting Cai et al.

Summary: An electrochemical-DNA (E-DNA) sensor was developed using DNA metallization as a signal reporter and hybridization chain reaction (HCR) as a signal amplification strategy. The sensor demonstrated superior sensing performance for trace ctDNA analysis, with a wide detection range and low detection limit. It also showed excellent selectivity, repeatability, stability, and recovery, making it a promising tool for clinical sample analysis.

BIOSENSORS-BASEL (2022)

Add to Collection
Article Chemistry, Analytical

An Ultrasensitive Electrochemical Biosensor Integrated by Nicking Endonuclease-Assisted Primer Exchange Reaction Cascade Amplification and DNA Nanosphere-Mediated Electrochemical Signal-Enhanced System for MicroRNA Detection

Sha Yu et al.

Summary: In this study, an ultrasensitive electrochemical biosensor was developed for the detection of miR-21 using cascade amplification and DNA nanotechnology. The biosensor showed wide detection range, low detection limit, and excellent selectivity, making it a powerful platform for early detection and molecular diagnosis.

ANALYTICAL CHEMISTRY (2022)

Add to Collection
Review Chemistry, Analytical

Recent progress in homogeneous electrochemical sensors and their designs and applications

Haiyin Li et al.

Summary: Electrochemical sensors are regarded as promising tools for sensitive and selective detection of analytes due to their rapid response, easy operation, and miniaturization. However, traditional sensors that immobilize electroactive dyes and recognizable elements are time-consuming and can distort the activity of bio-recognizable elements. Homogeneous electrochemical sensors provide a promising alternative, attracting significant attention worldwide. This review discusses recent research progress on the design, development, and application of homogeneous electrochemical sensors for target analytes, covering single to dual signals and single to multiple analytes. The present challenges and further advancements are also highlighted.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2022)

Add to Collection
Review Chemistry, Analytical

Recent Advances in Electrochemical Biosensors: Applications, Challenges, and Future Scope

Anoop Singh et al.

Summary: Electrochemical biosensors are a class of sensors that convert biological information into current or voltage, with applications in medical, food industry, and other fields. Machine learning is essential for interpreting large sensing data and improving sensors' sensitivity.

BIOSENSORS-BASEL (2021)

Add to Collection
Article Chemistry, Analytical

Precise Capture and Direct Quantification of Tumor Exosomes via a Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy

Limin Yang et al.

Summary: This study proposed a highly efficient dual-aptamer recognition system for precise isolation and quantification of tumor exosomes, achieving highly sensitive detection through signal amplification and ratiometric dual-signal strategies. The approach effectively circumvented systematic errors caused by external factors and tedious probe immobilization processes, displaying excellent reliability, improved accuracy, and ease of manipulation.

ANALYTICAL CHEMISTRY (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Protease Biosensor by Conversion of a Homogeneous Assay into a Surface-Tethered Electrochemical Analysis Based on Streptavidin-Biotin Interactions

Ning Xia et al.

Summary: This work proposed a new sensing strategy for protease detection by converting a homogeneous assay into a surface-tethered electrochemical analysis. With the simple principle of substrate-induced assembly of streptavidin, a dual-signal amplification was achieved with improved sensitivity. This method, with its high sensitivity, simple principle, and easy operation, can be augmented to design various surface-tethered biosensors for practical applications.

ACS SENSORS (2021)

Add to Collection
Article Chemistry, Analytical

Duplex-specific nuclease-based electrochemical biosensor for the detection of microRNAs by conversion of homogeneous assay into surface-tethered electrochemical analysis

Lin Liu et al.

Summary: A novel strategy for miRNA detection was proposed, converting homogeneous assay into surface-tethered electrochemical analysis. The method, utilizing dual signal amplification, showed a promising detection limit down to 10 aM for miRNAs in cell lysate. This one-step immobilization-free strategy may lead to the development of novel biosensors for detecting other biomarkers.

ANALYTICA CHIMICA ACTA (2021)

Add to Collection
Article Chemistry, Analytical

Stochastic Collision Electrochemistry from Single G-Quadruplex/Hemin: Electrochemical Amplification and MicroRNA Sensing

Hao Wang et al.

Summary: This study developed an electrochemical amplification strategy to monitor the electrocatalytic behavior of single G-quadruplex/hemin, and designed a hybridization chain reaction strategy for miRNA-15 detection. These provide a meaningful approach for nucleic acid sensing at the single molecule/particle level with good selectivity and sensitivity.

ANALYTICAL CHEMISTRY (2021)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive electrochemical assay for microRNA-21 based on CRISPR/Cas13a-assisted catalytic hairpin assembly

Ying Cui et al.

Summary: In this study, an ultrasensitive electrochemical biosensing platform for miRNA-21 assay was developed by combining the CRISPR-Cas13a system and catalytic hairpin assembly (CHA). The platform demonstrated high sensitivity with a low detection limit of 2.6 fM, showing great potential for early clinical diagnostic applications.

TALANTA (2021)

Add to Collection
Article Chemistry, Analytical

Electrochemical detection of kinase by converting homogeneous analysis into heterogeneous assay through avidin-biotin interaction

Yong Chang et al.

Summary: A novel heterogeneous electrochemical method for kinase detection was proposed in this work, which does not require immobilization of the probe during phosphorylation. The method captures the biotinylated phosphopeptide on a neutravidin-modified electrode and recognizes phosphate groups using conjugates of biotinylated Phos-tag and ferrocene-capped gold nanoparticles. This strategy is simple, sensitive, and specific, integrating the advantages of homogeneous reaction and heterogeneous detection.

TALANTA (2021)

Add to Collection
Article Chemistry, Analytical

Universal and Programmable Rolling Circle Amplification-CRISPR/Cas12a-Mediated Immobilization-Free Electrochemical Biosensor

Min Qing et al.

Summary: The study introduced the CRISPR/Cas system into an electrochemical biosensing platform for sensitive and specific detection of disease-related molecules. By utilizing modular rolling circle amplification and CRISPR/Cas12a, signal amplification was achieved. The flexibility and programmability of this strategy allow for the detection of various targets.

ANALYTICAL CHEMISTRY (2021)

Add to Collection
Article Chemistry, Physical

Redox Host-Guest Nanosensors Installed with DNA Gatekeepers for Immobilization-Free and Ratiometric Electrochemical Detection of miRNA

Xiyue Xie et al.

Summary: This study developed a host-guest assembly strategy to build redox nanosensors for immobilization-free and ratiometric electrochemical detection system. By utilizing miRNA triggering and NIR irradiation, the system achieved highly repeatable detection of miRNA, providing a new direction for the design of advanced electrochemical biosensors.

SMALL METHODS (2021)

Add to Collection
Article Chemistry, Analytical

Proximity hybridization triggered hybridization chain reaction for label-free electrochemical homogeneous aptasensors

Xianjiu Liao et al.

Summary: A label-free homogeneous electrochemical aptasensor was developed for detection of thrombin using proximity hybridization triggered hybridization chain reaction induced G-quadruplex formation. This method allows sensitive detection of thrombin with simplicity and low cost.

TALANTA (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Electrochemical-Based DNA Logic Devices Regulated by the Diffusion and Intercalation of Electroactive Dyes

Liping Zhu et al.

Summary: The study introduces an electrochemical molecular logic system based on DNA hybridization reactions, which triggers the release of electroactive dyes to generate electrochemical signals with opposite changes.

ACS APPLIED MATERIALS & INTERFACES (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Recent Progress in DNA Hybridization Chain Reaction Strategies for Amplified Biosensing

Hua Chai et al.

Summary: This article summarizes the assembly principles and applications of hybridization chain reaction (HCR) in DNA nanotechnology. HCR has excellent assembly kinetics and ease of operation, making it suitable for ultra-sensitive detection of various targets. Future advancements in overcoming challenges are needed for further development in this field.

ACS APPLIED MATERIALS & INTERFACES (2021)

Add to Collection
Review Chemistry, Multidisciplinary

DNAzyme-Based Biosensors: Immobilization Strategies, Applications, and Future Prospective

Shadman Khan et al.

Summary: DNAzymes have been extensively used in biosensors as molecular recognition elements or reporters, with immobilization strategy selection being crucial for sensor accuracy and sensitivity. Various immobilization approaches for DNAzymes within biosensors have been employed, with the selection of an appropriate strategy largely dependent on the desired application.

ACS NANO (2021)

Add to Collection
Article Chemistry, Analytical

An enzyme-free amplification strategy for sensitive assay of circulating tumor DNA based on wheel-like catalytic hairpin assembly and frame hybridization chain reaction

Shihua Luo et al.

Summary: This study developed a novel electrochemical biosensor for sensitive detection of ctDNA, utilizing wheel-like catalytic hairpin assembly and frame hybridization chain reaction, which significantly enhances the sensitivity of ctDNA detection.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Add to Collection
Article Chemistry, Analytical

Amperometric Bioplatforms To Detect Regional DNA Methylation with Single-Base Sensitivity

Eloy Povedano et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

Electrochemical Sensing of Exosomal MicroRNA Based on Hybridization Chain Reaction Signal Amplification with Reduced False-Positive Signals

Qunqun Guo et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

One-Step Synthesis of Methylene Blue-Encapsulated Zeolitic Imidazolate Framework for Dual-Signal Fluorescent and Homogeneous Electrochemical Biosensing

Jiafu Chang et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive lab-on-paper device via Cu/Co double-doped CeO2 nanospheres as signal amplifiers for electrochemical/visual sensing of miRNA-155

Chenxi Zhou et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

Add to Collection
Review Chemistry, Multidisciplinary

The Recent Development of Hybridization Chain Reaction Strategies in Biosensors

Chuyan Zhang et al.

ACS SENSORS (2020)

Add to Collection
Article Chemistry, Analytical

Zippering DNA Tetrahedral Hyperlink for Ultrasensitive Electrochemical MicroRNA Detection

Ying Wan et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Review Chemistry, Analytical

MicroRNAs in ovarian cancer and recent advances in the development of microRNA-based biosensors

Nahian Binte Aziz et al.

ANALYST (2020)

Add to Collection
Article Chemistry, Analytical

Nucleic Acid-Functionalized Metal-Organic Framework-Based Homogeneous Electrochemical Biosensor for Simultaneous Detection of Multiple Tumor Biomarkers

Jiafu Chang et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive Electrochemical Biosensor Developed by Probe Lengthening for Detection of Genomic DNA in Human Serum

Jin-Yuan Chen et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection
Article Chemistry, Analytical

Electrochemical selective detection of carnitine enantiomers coupling copper ion dependent DNAzyme with DNA assistant hybridization chain reaction

Fenfen Zhai et al.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2019)

Add to Collection
Article Chemistry, Analytical

Mesoporous Silica Containers and Programmed Catalytic Hairpin Assembly/Hybridization Chain Reaction Based Electrochemical Sensing Platform for MicroRNA Ultrasensitive Detection with Low Background

Hong Cheng et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive electrochemical microRNA-21 biosensor coupling with carboxylate-reduced graphene oxide-based signal-enhancing and duplex-specific nuclease-assisted target recycling

Qi Xiao et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Add to Collection
Article Chemistry, Analytical

Sensitive electrochemical biosensor for MicroRNAs based on duplex-specific nuclease-assisted target recycling followed with gold nanoparticles and enzymatic signal amplification

Hui Zhang et al.

ANALYTICA CHIMICA ACTA (2019)

Add to Collection
Article Chemistry, Analytical

Novel 2D-DNA-Nanoprobe-Mediated Enzyme-Free-Target-Recycling Amplification for the Ultrasensitive Electrochemical Detection of MicroRNA

Xiaolong Zhang et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection
Article Biophysics

A cascade autocatalytic strand displacement amplification and hybridization chain reaction event for label-free and ultrasensitive electrochemical nucleic acid biosensing

Zhiqiang Chen et al.

BIOSENSORS & BIOELECTRONICS (2018)

Add to Collection
Review Chemistry, Multidisciplinary

Chemical and Biological Sensing Using Hybridization Chain Reaction

Erik E. Augspurger et al.

ACS SENSORS (2018)

Add to Collection
Review Biotechnology & Applied Microbiology

Biosensors Using Hybridization Chain Reaction - Design and Signal Amplification Strategies of Hybridization Chain Reaction

Chae Rin Park et al.

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2018)

Add to Collection
Review Chemistry, Multidisciplinary

DNA hybridization chain reaction and DNA supersandwich self-assembly for ultrasensitive detection

Nannan Liu et al.

SCIENCE CHINA-CHEMISTRY (2017)

Add to Collection
Review Chemistry, Analytical

Hybridization chain reaction directed DNA superstructures assembly for biosensing applications

Dawei Yang et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2017)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive Homogeneous Electrochemical Detection of Transcription Factor by Coupled Isothermal Cleavage Reaction and Cycling Amplification Based on Exonuclease III

Lihua Lu et al.

ANALYTICAL CHEMISTRY (2017)

Add to Collection
Article Biophysics

Simultaneously electrochemical detection of microRNAs based on multifunctional magnetic nanoparticles probe coupling with hybridization chain reaction

Yan-Hong Yuan et al.

BIOSENSORS & BIOELECTRONICS (2017)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive Electrochemical Detection of miRNA-21 Using a Zinc Finger Protein Specific to DNA-RNA Hybrids

Chiew San Fang et al.

ANALYTICAL CHEMISTRY (2017)

Add to Collection
Article Chemistry, Analytical

An electrochemical biosensor for DNA detection based on tungsten disulfide/multi-walled carbon nanotube composites and hybridization chain reaction amplification

Xue Liu et al.

SENSORS AND ACTUATORS B-CHEMICAL (2016)

Add to Collection
Review Chemistry, Analytical

Immobilization-free DNA-based homogeneous electrochemical biosensors

Fang-Ting Zhang et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)

Add to Collection
Article Nanoscience & Nanotechnology

In Situ DNA-Templated Synthesis of Silver Nanoclusters.for Ultrasensitive and Label-Free Electrochemical Detection of MicroRNA

Cuiyun Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

Add to Collection
Article Chemistry, Analytical

An electrochemical microRNAs biosensor with the signal amplification of alkaline phosphatase and electrochemical-chemical-chemical redox cycling

Ning Xia et al.

ANALYTICA CHIMICA ACTA (2015)

Add to Collection
Article Chemistry, Analytical

Label-Free and Enzyme-Free Homogeneous Electrochemical Biosensing Strategy Based on Hybridization Chain Reaction: A Facile, Sensitive, and Highly Specific MicroRNA Assay

Ting Hou et al.

ANALYTICAL CHEMISTRY (2015)

Add to Collection
Article Biophysics

Ultrasensitive and selective signal-on electrochemical DNA detection via exonuclease III catalysis and hybridization chain reaction amplification

Wang Ren et al.

BIOSENSORS & BIOELECTRONICS (2015)

Add to Collection
Article Chemistry, Multidisciplinary

MicroRNA detection based on analyte triggered nanoparticle localization on a tetrahedral DNA modified electrode followed by hybridization chain reaction dual amplification

Peng Miao et al.

CHEMICAL COMMUNICATIONS (2015)

Add to Collection
Article Chemistry, Analytical

Aptamer-based fluorescent solid-phase thrombin assay using a silver-coated glass substrate and signal amplification by glucose oxidase

Yubin Li et al.

MICROCHIMICA ACTA (2015)

Add to Collection
Article Chemistry, Analytical

Exonuclease III-Aided Autocatalytic DNA Biosensing Platform for Immobilization-Free and Ultrasensitive Electrochemical Detection of Nucleic Acid and Protein

Shufeng Liu et al.

ANALYTICAL CHEMISTRY (2014)

Add to Collection
Article Chemistry, Analytical

Hybridization Chain Reaction Amplification of MicroRNA Detection with a Tetrahedral DNA Nanostructure-Based Electrochemical Biosensor

Zhilei Ge et al.

ANALYTICAL CHEMISTRY (2014)

Add to Collection
Article Biophysics

Ultrasensitive electrochemical DNA detection based on dual amplification of circular strand-displacement polymerase reaction and hybridization chain reaction

Cui Wang et al.

BIOSENSORS & BIOELECTRONICS (2013)

Add to Collection
Article Chemistry, Analytical

Ultrasensitive Solution-Phase Electrochemical Molecular Beacon-Based DNA Detection with Signal Amplification by Exonuclease III-Assisted Target Recycling

Feng Xuan et al.

ANALYTICAL CHEMISTRY (2012)

Add to Collection
Article Multidisciplinary Sciences

Triggered amplification by hybridization chain reaction

RM Dirks et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.