4.6 Article

Macrophages mediate psoriasis via Mincle-dependent mechanism in mice

Related references

Note: Only part of the references are listed.
Article Immunology

PU.1 Regulates Cathepsin S Expression in Large Yellow Croaker (Larimichthys crocea) Macrophages

Xiang-Yang Zhang et al.

Summary: This study identified two sub-cloned macrophage cell lines with different morphologies and demonstrated that the transcription factor PU.1 plays a role in regulating the expression of the CTSS gene in these cells.

FRONTIERS IN IMMUNOLOGY (2022)

Article Dermatology

Psoriasis and mortality in the United States: Data from the National Health and Nutrition Examination Survey

Yevgeniy R. Semenov et al.

Summary: The study indicates that psoriasis is significantly associated with all-cause mortality, with this relationship partially mediated by an increased prevalence of cardiovascular, infectious, and neoplastic disorders among patients with psoriasis.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

Article Immunology

Vitamin D3-Induced Promotor Dissociation of PU.1 and YY1 Results in FcεRI Reduction on Dendritic Cells in Atopic Dermatitis

Nadine Herrmann et al.

Summary: Atopic dermatitis is a severe inflammatory skin disease where Langerhans cells and IDCs express high-affinity IgE receptors and sense allergens. Vitamin D-3 can directly reduce Fc epsilon RI expression on dendritic cells, inhibiting IgE-mediated inflammatory processes in AD patients with allergic sensitization.

JOURNAL OF IMMUNOLOGY (2021)

Review Biochemistry & Molecular Biology

Skin Barrier Dysregulation in Psoriasis

Andreas Orsmond et al.

Summary: The skin barrier consists of a physical barrier in the epidermis and an immune barrier in both dermis and epidermis, which cooperate to maintain skin homeostasis and human health. Dysregulation can lead to various skin diseases, with psoriasis being one of the most prevalent due to disrupted barrier function. Recent research has focused on understanding disease pathogenesis involving keratinocytes, immune cells, genetic and environmental factors, and advancements in current and future treatments.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Biochemistry & Molecular Biology

Current Concepts of Psoriasis Immunopathogenesis

Marijana Vicic et al.

Summary: Psoriasis is a chronic, immune-mediated inflammatory disease that affects skin, joints, and other organs. It is triggered by genetic predisposition and environmental factors, leading to complex inflammatory cascades through the IL-23/Th17 pathway. The disease has a major impact on individuals' lives due to its comorbidities and social/emotional aspects.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Immunology

PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages

Takuya Yashiro et al.

Summary: The study revealed that PU.1 and IRF8 are involved in the monocytic lineage-specific expression of NLRP3 by binding to regulatory elements within its promoter. Knockdown of PU.1 and IRF8 suppresses the activity of the NLRP3 inflammasome.

FRONTIERS IN IMMUNOLOGY (2021)

Review Immunology

Epidemiology of major chronic inflammatory immune-related skin diseases in 2019

Elena Pezzolo et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Franziska Herster et al.

NATURE COMMUNICATIONS (2020)

Review Medicine, General & Internal

Pathophysiology, Clinical Presentation, and Treatment of Psoriasis A Review

April W. Armstrong et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Immunology

C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury

Miyako Tanaka et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Review Biochemistry & Molecular Biology

Psoriasis Pathogenesis and Treatment

Adriana Rendon et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Pathology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

Massimo Locati et al.

Annual Review of Pathology-Mechanisms of Disease (2019)

Letter Dermatology

Psoriasis, arthritis, and pyoderma gangrenosum: an autoinflammatory syndrome or a coincidence?

Zoe Apalla et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2019)

Review Immunology

Implications of macrophage polarization in autoimmunity

Samanta C. Funes et al.

IMMUNOLOGY (2018)

Review Cell Biology

Macrophage polarization: the link between inflammation and related diseases

Samina Bashir et al.

INFLAMMATION RESEARCH (2016)

Article Oncology

Macrophage-mediated psoriasis can be suppressed by regulatory T lymphocytes

Rafael Leite Dantas et al.

JOURNAL OF PATHOLOGY (2016)

Article Multidisciplinary Sciences

Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

Tej Pratap Singh et al.

NATURE COMMUNICATIONS (2016)

Article Medicine, General & Internal

Psoriasis

Wolf-Henning Boehncke et al.

LANCET (2015)

Article Allergy

Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages

Patrick M. Brunner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Review Dermatology

Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence

Rosa Parisi et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)

Article Medicine, Research & Experimental

Macrophage plasticity and polarization: in vivo veritas

Antonio Sica et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Review Immunology

Protective and pathogenic functions of macrophage subsets

Peter J. Murray et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Dermatology

A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis

Judilyn Fuentes-Duculan et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)

Editorial Material Immunology

Sensing necrosis with Mincle

Gordon D. Brown

NATURE IMMUNOLOGY (2008)

Article Immunology

Mincle is an ITAM-coupled activating receptor that senses damaged cells

Sho Yamasaki et al.

NATURE IMMUNOLOGY (2008)

Article Dermatology

Incidence and risk factors for psoriasis in the general population

Consuelo Huerta et al.

ARCHIVES OF DERMATOLOGY (2007)

Article Medicine, General & Internal

Psoriasis 1 - Pathogenesis and clinical features of psoriasis

Christopher E. M. Griffiths et al.

LANCET (2007)

Article Medicine, Research & Experimental

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

Honglin Wang et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Medicine, Research & Experimental

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

Athanasios Stratis et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)