Related references
Note: Only part of the references are listed.Lipoprotein(a): A Genetically Determined, Causal, and Prevalent Risk Factor for Atherosclerotic Cardiovascular Disease: A Scientific Statement From the American Heart Association
Gissette Reyes-Soffer et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2022)
Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions
Donna M. Conlon et al.
JOURNAL OF CLINICAL INVESTIGATION (2022)
Latest impact of engineered human liver platforms on drug development
Chase P. Monckton et al.
APL BIOENGINEERING (2021)
Spending on Cardiovascular Disease and Cardiovascular Risk Factors in the United States: 1996 to 2016
Maxwell Birger et al.
CIRCULATION (2021)
Outcomes of lipid control in secondary prevention of coronary artery disease in Finland: A 24-month follow-up after acute coronary syndrome
Riikka-Leena Leskela et al.
ATHEROSCLEROSIS (2020)
Worldwide Prevalence of Familial Hypercholesterolemia Meta-Analyses of 11 Million Subjects
Sabina O. Beheshti et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)
The Use of Human Pluripotent Stem Cells for Modeling Liver Development and Disease
James A. Heslop et al.
HEPATOLOGY (2019)
Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Strain and Species Comparison Studies During Drug Development
Brenton R. Ware et al.
GENE EXPRESSION (2019)
iPSC-Derived Hepatocytes as a Platform for Disease Modeling and Drug Discovery
James L. Corbett et al.
FRONTIERS IN MEDICINE (2019)
Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines
Alexander J. Kvist et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100
Jaume Amengual et al.
CIRCULATION RESEARCH (2018)
Lipid transfer proteins in the assembly of apoB-containing lipoproteins
Alaa Sirwi et al.
JOURNAL OF LIPID RESEARCH (2018)
Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017
Christopher J. L. Murray et al.
LANCET (2018)
A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome
Ran Jing et al.
CELL REPORTS (2018)
Lomitapide for the treatment of hypercholesterolemia
Amanda J. Berberich et al.
EXPERT OPINION ON PHARMACOTHERAPY (2017)
Treatment of Cholesterol in 2017
Harlan M. Krumholz
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress
Ying Liu et al.
CELL REPORTS (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Modeling Inborn Errors of Hepatic Metabolism Using Induced Pluripotent Stem Cells
Behshad Pournasr et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia
Max A. Cayo et al.
CELL STEM CELL (2017)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes
Sunil K. Mallanna et al.
STEM CELL REPORTS (2016)
Prediction of Drug Clearance and Drug-Drug Interactions in Microscale Cultures of Human Hepatocytes
Christine Lin et al.
DRUG METABOLISM AND DISPOSITION (2016)
Contemporary Aspects of the Biology and Therapeutic Regulation of the Microsomal Triglyceride Transfer Protein
Amanda J. Hooper et al.
CIRCULATION RESEARCH (2015)
Lomitapide and Mipomersen Two First-in-Class Drugs for Reducing Low-Density Lipoprotein Cholesterol in Patients With Homozygous Familial Hypercholesterolemia
Daniel J. Rader et al.
CIRCULATION (2014)
Lipid lowering with PCSK9 inhibitors
Razvan T. Dadu et al.
NATURE REVIEWS CARDIOLOGY (2014)
Discontinuation of Statins in Routine Care Settings A Cohort Study
Huabing Zhang et al.
ANNALS OF INTERNAL MEDICINE (2013)
Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting
Jeffrey M. Chamberlain et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Emerging LDL therapies: Mipomersen-antisense oligonudeotide therapy in the management of hypercholesterolemia
Peter P. Toth
JOURNAL OF CLINICAL LIPIDOLOGY (2013)
Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
Ewa C. S. Ellis et al.
PLOS ONE (2013)
Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
Salman R. Khetani et al.
TOXICOLOGICAL SCIENCES (2013)
The regulation of ApoB metabolism by insulin
Mary E. Haas et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial
Maartje E. Visser et al.
EUROPEAN HEART JOURNAL (2012)
JD Induced Pluripotent Stem Cell-Derived Hepatocytes Faithfully Recapitulate the Pathophysiology of Familial Hypercholesterolemia
Max A. Cayo et al.
HEPATOLOGY (2012)
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism
Alanna Strong et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Principles of early drug discovery
J. P. Hughes et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Reliability of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B measurement
John H. Contois et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2011)
Illustration of SSMD, z Score, SSMD*, z* Score, and t Statistic for Hit Selection in RNAi High-Throughput Screens
Xiaohua Douglas Zhang
JOURNAL OF BIOMOLECULAR SCREENING (2011)
Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors
Karim Si-Tayeb et al.
BMC DEVELOPMENTAL BIOLOGY (2010)
Highly Efficient Generation of Human Hepatocyte-Like Cells from Induced Pluripotent Stem Cells
Karim Si-Tayeb et al.
HEPATOLOGY (2010)
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
Frederick J. Raal et al.
LANCET (2010)
Safety signal dampens reception for mipomersen antisense
Jim Kling
NATURE BIOTECHNOLOGY (2010)
The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism
Henry N. Ginsberg et al.
JOURNAL OF LIPID RESEARCH (2009)
The SLCO1B1*5 Genetic Variant Is Associated With Statin-Induced Side Effects
Deepak Voora et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Evaluation of two dual-functional primers and a tribochemical surface modification system applied to the bonding of an indirect composite resin to metals
Hiroaki Yanagida et al.
ODONTOLOGY (2009)
Regulation of Bile Acid and Cholesterol Metabolism by PPARs
Tiangang Li et al.
PPAR RESEARCH (2009)
Autophagy of an oxidized, aggregated protein beyond the ER - A pathway for remarkably late-stage quality control
Edward A. Fisher et al.
AUTOPHAGY (2008)
A maximum common substructure-based algorithm for searching and predicting drug-like compounds
Yiqun Cao et al.
BIOINFORMATICS (2008)
Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response
Deepak Voora et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2008)
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: A pathway for late-stage quality control
Meihui Pan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Microscale culture of human liver cells for drug development
Salman R. Khetani et al.
NATURE BIOTECHNOLOGY (2008)
Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice
Hisaya Azuma et al.
NATURE BIOTECHNOLOGY (2007)
Lipid disorders and mutations in the APOB gene
AJ Whitfield et al.
CLINICAL CHEMISTRY (2004)
Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER
W Liao et al.
JOURNAL OF LIPID RESEARCH (2003)
Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly
MM Hussain et al.
JOURNAL OF LIPID RESEARCH (2003)
Performance of similarity measures in 2D fragment-based similarity searching: Comparison of structural descriptors and similarity coefficients
X Chen et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2002)
Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation
A Kulinski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Complexity in the secretory pathway: The assembly and secretion of apolipoprotein B-containing lipoproteins
EA Fisher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 mutation
X Lin et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
The triple threat to nascent apolipoprotein B - Evidence for multiple, distinct degradative pathways
EA Fisher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion
GK Leung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
