4.7 Article

Impacts of Mir146a Genotypes on Bladder Cancer Risk in Taiwan

Related references

Note: Only part of the references are listed.
Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Article Oncology

MicroRNA-146a promotes proliferation, migration, and invasion of HepG2 via regulating FLAP

Huihui Wang et al.

Summary: This study found that miR-146a is overexpressed in HCC tissues and liver cancer cells, while FLAP protein and mRNA are suppressed. The experimental results showed that miR-146a can target FLAP mRNA, and silencing miR-146a or restoring FLAP can reduce the proliferation, cell cycle progression, migration, and invasion of HepG2 cells, indicating that miR-146a has a stimulatory role in HepG2 cells.

CANCER CELL INTERNATIONAL (2022)

Review Oncology

The Impact of Meat Intake on Bladder Cancer Incidence: Is It Really a Relevant Risk?

Achille Aveta et al.

Summary: Meat consumption is associated with bladder cancer incidence, with the specific association depending on the type of meat, cooking method, and temperature. Reducing the intake of red and processed meat can lower the risk of bladder cancer development.

CANCERS (2022)

Article Oncology

Effect of miR-196a2 rs11614913 Polymorphism on Cancer Susceptibility: Evidence From an Updated Meta-Analysis

Md. Abdul Aziz et al.

Summary: The miR-196a2 rs11614913 variant is significantly associated with overall cancer susceptibility, particularly in Asians and Africans. It is also correlated with breast, hepatocellular, lung, oral, and renal cell cancer.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2022)

Review Oncology

Urinary biomarkers in bladder cancer: A review of the current landscape and future directions

Kenrick Ng et al.

Summary: This narrative review discusses established and emerging urinary biomarkers for non-muscle invasive bladder cancer, highlighting the limitations of classical FDA-approved protein biomarkers. Advancements in epigenetic and genetic markers as well as extracellular vesicles have shown promise in enhancing sensitivity and specificity in bladder cancer diagnosis. The future focus will be on utilizing these markers in combination to create predictive signatures for everyday clinical practice.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2021)

Article Biochemistry & Molecular Biology

Circulating miRNAs Act as Diagnostic Biomarkers for Bladder Cancer in Urine

Jen-Tai Lin et al.

Summary: The study showed that certain miRNAs in urine could potentially serve as noninvasive biomarkers for diagnosing bladder cancer, with implications for early detection and patient survival. Further validation in larger cohorts is necessary to confirm the clinical utility of urinary miRNAs in bladder cancer diagnosis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Oncology

Evaluation Expression of miR-146a and miR-155 in Non-Small-Cell Lung Cancer Patients

Neda K. Dezfuli et al.

Summary: The study found that miR-146a expression was significantly downregulated in NSCLC patients, while IL-6 and TGF-beta levels were elevated. The frequencies of immune cells CD3+ CTLA-4+ and Treg cells were also higher in patients.

FRONTIERS IN ONCOLOGY (2021)

Article Medicine, Research & Experimental

Association of Matrix Metalloproteinase-1 Genotypes With Bladder Cancer Risk

Cheng-Hsi Liao et al.

Summary: The results of the study suggest that MMP1 rs1799750 genotypes do not play a significant role in determining personal susceptibility to bladder cancer in Taiwanese individuals.

IN VIVO (2021)

Article Biotechnology & Applied Microbiology

The role of single nucleotide polymorphisms of miRNAs 100 and 146a as prognostic factors for prostate cancer

Juliana Alves de Camargo et al.

Summary: This study evaluated the role of SNP rs1834306 of miR100 and rs2910164 of miR146a in the development and prognosis of prostate cancer, finding that the SNP of miR146a acts as a poor prognostic factor, while the SNP of miR100 is linked to better prognostic data. MiR100 was overexpressed in prostate cancer with worse prognostic factors.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS (2021)

Article Biochemistry & Molecular Biology

miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1

Jun Chen et al.

JOURNAL OF BIOCHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Tumor Necrosis Factor-Induced miR-146a Upregulation Promotes Human Lung Adenocarcinoma Metastasis by Targeting Merlin

Nilda C. Sanchez et al.

DNA AND CELL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

A genetic variant in microRNA-146a is associated with sporadic breast cancer in a Southern Brazilian Population

Heloisa Magagnin Brincas et al.

GENETICS AND MOLECULAR BIOLOGY (2019)

Article Environmental Sciences

Spatial Analysis of Ambient PM2.5 Exposure and Bladder Cancer Mortality in Taiwan

Hsin-Ling Yeh et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2017)

Review Oncology

Urologic cancer in Taiwan

Chi-Feng Hung et al.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2016)

Article Oncology

miR146a-mediated targeting of FANCM during inflammation compromises genome integrity

Devakumar Sundaravinayagam et al.

ONCOTARGET (2016)

Article Environmental Sciences

Parity, Age at First Birth, and Risk of Death from Bladder Cancer: A Population-Based Cohort Study in Taiwan

Hui-Fen Chiu et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2016)

Article Biochemistry & Molecular Biology

Merlin negative regulation by miR-146a promotes cell transformation

Erick I. Perez-Garcia et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Oncology

Common genetic polymorphisms in pre-microRNAs and risk of bladder cancer

Shi Deng et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2015)

Article Oncology

Genetic Variants in miRNAs Predict Bladder Cancer Risk and Recurrence

Meilin Wang et al.

CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

Investigative Role of Pre-MicroRNAs in Bladder Cancer Patients: A Case-Control Study in North India

Rama Devi Mittal et al.

DNA AND CELL BIOLOGY (2011)

Review Oncology

The microRNA pathway and cancer

Pieter Bas Kwak et al.

CANCER SCIENCE (2010)

Review Biotechnology & Applied Microbiology

Targeting microRNAs in cancer: rationale, strategies and challenges

Ramiro Garzon et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Article Medical Laboratory Technology

Detection and characterization of placental MicroRNAs in maternal plasma

Stephen S. C. Chim et al.

CLINICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Serum MicroRNAs Are Promising Novel Biomarkers

Shlomit Gilad et al.

PLOS ONE (2008)

Article Genetics & Heredity

Impaired microRNA processing enhances cellular transformation and tumorigenesis

Madhu S. Kumar et al.

NATURE GENETICS (2007)

Review Oncology

Oncomirs - microRNAs with a role in cancer

A Esquela-Kerscher et al.

NATURE REVIEWS CANCER (2006)

Article Multidisciplinary Sciences

The functions of animal microRNAs

V Ambros

NATURE (2004)