☆ 4.7 Review

Multi-Omics and Management of Follicular Carcinoma of the Thyroid

BIOMEDICINES (2023)

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Annotation-Free Deep Learning-Based Prediction of Thyroid Molecular Cancer Biomarker BRAF (V600E) from Cytological Slides

Ching-Wei Wang et al.

Summary: Thyroid cancer is the most common endocrine cancer, and fine needle aspiration cytology (FNAC) is the most cost-effective and accurate diagnostic method for diagnosing papillary thyroid cancer (PTC). Identifying the BRAF (V600E) mutation in thyroid neoplasia is beneficial for prognosis prediction and potential targeted therapies.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

[18F]FDG-PET/CT to prevent futile surgery in indeterminate thyroid nodules: a blinded, randomised controlled multicentre trial

Elizabeth J. de Koster et al.

Summary: The study aimed to assess the impact of an [F-18]FDG-PET/CT-driven diagnostic workup on patients with indeterminate thyroid nodules. The results showed that this workup accurately reduced futile surgeries by 40% and should be limited to non-Hurthle cell nodules.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Exosomes as a new frontier of cancer liquid biopsy

Dan Yu et al.

Summary: Liquid biopsy, a revolutionary strategy for cancer diagnosis and prognosis prediction, uses minimally invasive detection through biofluids such as blood, saliva, and urine. Exosomes, a subset of extracellular vesicles, play a crucial role in intercellular communication and are considered as potential biomarkers in liquid biopsy. However, the lack of high-quality separation and component analysis methods has limited the further clinical application of exosomes.

MOLECULAR CANCER (2022)

Add to Collection
Article Oncology

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

Poupak Fallahi et al.

Summary: Thyroid cancer is a common cancer with a rising incidence worldwide. Surgery is the primary treatment strategy, but some patients experience recurrence during follow-up. Resistance to radioactive iodine is a poor prognostic factor. Significant advances have been made in understanding the molecular pathways of thyroid cancer, leading to the development of tyrosine kinase inhibitors as new treatment options. However, further research is needed.

SEMINARS IN CANCER BIOLOGY (2022)

Add to Collection
Article Endocrinology & Metabolism

Surgical Management of Low-/Intermediate-Risk Node Negative Thyroid Cancer: A Single-Institution Study Using Propensity Matching Analysis to Compare Thyroid Lobectomy and Total Thyroidectomy

Danielli Matsuura et al.

Summary: This study aimed to compare the effectiveness of total thyroidectomy (TT) and thyroid lobectomy (TL) in patients with low-/intermediate-risk T1T2N0/Nx thyroid cancer. Using propensity score matching, the study found that patients selected for TL had similar survival outcomes to a comparable group treated with TT.

THYROID (2022)

Add to Collection
Article Surgery

Impact of Extent of Surgery on Long-Term Prognosis of Follicular Thyroid Carcinoma Without Extrathyroidal Extension and Distant Metastasis

Xiaofei Wang et al.

Summary: For FTC patients without extrathyroidal extension and distant metastasis, total thyroidectomy (TT) and thyroid lobectomy (LT) have equivalent disease-specific survival (DSS) outcomes regardless of tumor size. Additional thyroidectomy after LT may not be necessary unless patients experience recurrence, but recurrence rates and metastasis development were not evaluated in this study.

WORLD JOURNAL OF SURGERY (2022)

Add to Collection
Article Medicine, Research & Experimental

KDM1A promotes thyroid cancer progression and maintains stemness through the Wnt/β-catenin signaling pathway

Wei Zhang et al.

Summary: The study reveals that KDM1A regulates the stemness of thyroid cancer and promotes cancer progression through the Wnt/beta-catenin pathway. Inhibiting KDM1A can significantly inhibit thyroid cancer progression and enhance sensitivity to chemotherapy.

THERANOSTICS (2022)

Add to Collection
Review Oncology

Molecular diagnosis and targeted treatment of advanced follicular cell-derived thyroid cancer in the precision medicine era

Jaume Capdevila et al.

Summary: Most malignant thyroid tumours are initially treated with surgery or a combination of surgery and radioactive iodine therapy. However, in patients with metastatic disease, many tumours become refractory to radioactive iodine (RAI), and these patients require alternative treatments, such as locoregional therapies and/or systemic treatment with multikinase inhibitors. Targeted therapies based on genetic alterations have shown clinical efficacy in thyroid cancer, including NTRK gene fusions, RET and BRAF inhibitions. Effective testing strategies for these genetic alterations are crucial for identifying patients who could benefit from targeted treatments.

CANCER TREATMENT REVIEWS (2022)

Add to Collection
Article Endocrinology & Metabolism

Assesment of attainment of recommended TSH levels and levothyroxine compliance in differentiated thyroid cancer patients

Dilek Gogas Yavuz et al.

Summary: The study aimed to investigate TSH levels, adherence to LT4 suppression treatment, and the frequency of reaching target TSH levels in DTC patients after surgery. The results showed that a majority of patients did not achieve target TSH levels, and adherence to treatment had an impact on TSH levels. Simplified and practical guidelines are needed to achieve TSH targets.

CLINICAL ENDOCRINOLOGY (2022)

Add to Collection
Article Endocrinology & Metabolism

Overview of the 2022 WHO Classification of Thyroid Neoplasms

Zubair W. Baloch et al.

Summary: This review summarizes the changes in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new classification provides a more detailed understanding of the different types of thyroid tumors based on their cell of origin, pathologic features, molecular profiles, and biological behavior. It also introduces new categories, such as thyroid follicular nodular disease, non-invasive follicular thyroid neoplasm with papillary-like nuclear features, and high-grade differentiated thyroid carcinomas. The classification emphasizes the importance of biomarkers in diagnosis and prognosis.

ENDOCRINE PATHOLOGY (2022)

Add to Collection
Review Biochemistry & Molecular Biology

State of the Art in the Current Management and Future Directions of Targeted Therapy for Differentiated Thyroid Cancer

Horatiu Silaghi et al.

Summary: This article summarizes the conventional management of differentiated thyroid cancer (DTC) and introduces the first-line and alternative approaches using tyrosine kinase inhibitors (TKIs) in treating refractory DTC. It also discusses strategies to overcome resistance to MAPK and PI3K pathway inhibitors. Additionally, the article highlights the latest achievements in redifferentiation therapy, immunotherapy, and targeted gene rearrangement therapies for advanced DTC.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection
Article Oncology

Stratification of follicular thyroid tumours using data-independent acquisition proteomics and a comprehensive thyroid tissue spectral library

Yaoting Sun et al.

Summary: Thyroid nodules are common in about 60% of the population. Differentiating between follicular adenoma (FA) and carcinoma (FTC) is a challenge in thyroid nodule diagnosis. This study presents a comprehensive thyroid spectral library and identifies nine proteins that could potentially distinguish FA and FTC.

MOLECULAR ONCOLOGY (2022)

Add to Collection
Article Oncology

The Role of Artificial Intelligence in Early Cancer Diagnosis

Benjamin Hunter et al.

Summary: This article emphasizes the importance of early cancer diagnosis and the potential of machine learning in revolutionizing early cancer diagnosis. It discusses how artificial intelligence algorithms can assist doctors in diagnosis and presents some key artificial intelligence approaches and data types, as well as a discussion on the potential clinical implications and limitations.

CANCERS (2022)

Add to Collection
Review Surgery

A rare case of follicular thyroid carcinoma metastasis to the sacral region: A case report with literature review

Berrada Omar et al.

Summary: This case report describes a rare case of metastatic thyroid follicular carcinoma to the sacral region in a 74-year-old woman with a history of right thyroid lobectomy. Treatment included analgesic radiotherapy, surgical totalisation of thyroidectomy, and Radioactive Iodine, leading to a significant reduction in symptoms and improved quality of life. Early detection of rare metastases in thyroid cancer patients is crucial for improving survival rates and quality of life.

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS (2022)

Add to Collection
Article Otorhinolaryngology

EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles

Noha Elsherbini et al.

Summary: This study investigated the prevalence and co-mutations of EIF1AX mutations in thyroid nodules, and found that the coexistence of EIF1AX mutations with other driver mutations increases the risk of malignancy. These findings can assist clinicians in making treatment decisions for patients with thyroid nodules.

JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2022)

Add to Collection
Article Oncology

The miR-199a-5p/PD-L1 axis regulates cell proliferation, migration and invasion in follicular thyroid carcinoma

Jianguang Lin et al.

Summary: This study revealed that PD-L1 expression was elevated in follicular thyroid carcinoma (FTC) and was closely associated with tumor aggressiveness and progression. MiR-199a-5p has a functional role in the progression and metastasis of FTC by regulating PD-L1 and Claudin-1 expression.

BMC CANCER (2022)

Add to Collection
Review Endocrinology & Metabolism

Meta-analysis of TSH suppression therapy and the risk of cardiovascular events after thyroid cancer surgery

Xiao Yang et al.

Summary: This study investigated the relationship between TSH suppression therapy and cardiovascular events in patients with thyroid cancer after surgery. The results showed that TSH suppression therapy increases the risk of atrial fibrillation in patients. Furthermore, it was found that the patients had higher heart rate, systolic blood pressure, and diastolic blood pressure compared to the control group.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Review Oncology

Revisiting the Warburg Effect with Focus on Lactate

Eva Kocianova et al.

Summary: This review discusses the role and significance of lactate in cancer, as well as recent findings on lactate metabolism and signaling pathways in cancer.

CANCERS (2022)

Add to Collection
Article Chemistry, Analytical

Personal Digital Twin: A Close Look into the Present and a Step towards the Future of Personalised Healthcare Industry

Radhya Sahal et al.

Summary: Digital twins are crucial for revolutionizing the healthcare industry through personalized, intelligent, and proactive healthcare. Personal digital twins, as an enhanced version of digital twins, can provide valuable insights for accurate decision making and treatment selection for patients. However, personal digital twins are still in their early stages of development, and more efforts are needed.

SENSORS (2022)

Add to Collection
Article Endocrinology & Metabolism

Proteotypic Differences of Follicular-Patterned Thyroid Neoplasms

Dongdong Huang et al.

Summary: This study investigated the molecular differences among follicular-patterned thyroid tumors through proteomic analysis. The results identified differentially regulated proteins that can differentiate between different types of thyroid tumors.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Review Endocrinology & Metabolism

Target Therapy in Thyroid Cancer: Current Challenge in Clinical Use of Tyrosine Kinase Inhibitors and Management of Side Effects

Ivana Puliafito et al.

Summary: Thyroid cancer is the most common endocrine malignancy, and its subtypes have been studied for novel therapeutic options. These treatments often come with side effects that require optimal management.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Article Endocrinology & Metabolism

Efficacy of radiofrequency ablation for metastatic papillary thyroid cancer with and without initial biochemical complete status

Wen-Chieh Chen et al.

Summary: This study demonstrates that RFA can achieve both structural and biochemical improvements for locoregionally recurrent thyroid cancer, with a low complication rate. Nearly half of the patients achieved an excellent response after RFA, while a favorable treatment response can be achieved despite the lesion abutting the trachea, with a mean VRR of 84.74%.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Article Biology

High frequency of KRAS and EGFR mutation profiles in BRAF-negative thyroid carcinomas in Indonesia

Didik Setyo Heriyanto et al.

Summary: This study analyzed KRAS and EGFR mutation profiles in BRAF-V600E negative thyroid cancer samples and found that nearly half of the thyroid carcinoma samples harbored either KRAS or EGFR mutations. This suggests that testing for RAS and EGFR mutations may be warranted for further therapeutic consideration in BRAF-V600E negative thyroid carcinoma samples.

BMC RESEARCH NOTES (2022)

Add to Collection
Article Endocrinology & Metabolism

An artificial intelligence ultrasound system's ability to distinguish benign from malignant follicular-patterned lesions

Dong Xu et al.

Summary: This study evaluated the application value of a generally trained AI automatic diagnosis system in malignancy diagnosis of FPTL and compared its performance with radiologists of different experience levels. The results showed that the AI system had higher accuracy than the radiologists, but the radiologists had higher sensitivity and specificity.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Editorial Material Endocrinology & Metabolism

Editorial: The role of genetic alterations in thyroid carcinoma

Joachim Feldkamp

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Review Oncology

The Immune Landscape of Papillary Thyroid Cancer in the Context of Autoimmune Thyroiditis

Fabiana Pani et al.

Summary: The relationship between papillary thyroid cancer (PTC) and Hashimoto's thyroiditis has been the subject of debate. Emerging evidence from a novel mouse model suggests that pre-existing thyroiditis has a beneficial effect on PTC growth and progression. A better understanding of the immune response and the molecular biomarkers connecting inflammation and PTC is crucial for future research and potential implications in cancer immunotherapy.

CANCERS (2022)

Add to Collection
Review Nutrition & Dietetics

Iodine nutrition and papillary thyroid cancer

Xueqi Zhang et al.

Summary: The reasons for the increasing incidence of thyroid cancer are unclear, but lifestyle, environmental factors, and complications may play a role. Iodine intake may affect papillary thyroid carcinoma, but the available evidence is limited due to various factors.

FRONTIERS IN NUTRITION (2022)

Add to Collection
Review Endocrinology & Metabolism

Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach

Chan Kwon Jung et al.

Summary: The fifth edition of the WHO classification of thyroid neoplasms in 2022 introduces new tumor types, subtypes, and a grading system, providing more detailed and refined classifications for thyroid tumors. The inclusion of salivary gland-type carcinomas of the thyroid and thyroid tumors of uncertain histogenesis as new categories are of significant clinical relevance.

ENDOCRINOLOGY AND METABOLISM (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Machine learning on thyroid disease: a review

Kwang-Sig Lee et al.

Summary: This study reviews the recent progress of machine learning for the early diagnosis of thyroid disease and finds that different machine learning methods are suitable for different types of data.

FRONTIERS IN BIOSCIENCE-LANDMARK (2022)

Add to Collection
Article Endocrinology & Metabolism

Thyroid and Breast Cancer in 2 Sisters With Monoallelic Mutations in the Ataxia Telangiectasia Mutated (ATM) Gene

Fabiola Y. Miasaki et al.

Summary: A monoallelic ATM gene mutation, in conjunction with other genetic and/or nongenetic factors, may increase the risk of developing PTC and breast cancer.

JOURNAL OF THE ENDOCRINE SOCIETY (2022)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

Thyroid Follicular Epithelial Cell-Derived Cancer: New Approaches and Treatment Strategies

Julie Bolin

Summary: Thyroid cancer incidence has risen in the past 30 years, but patient mortality rates have not significantly increased. Advanced detection methods like high-resolution imaging aid in early detection and characterization of thyroid malignancies. Research on genetic mutations is essential for understanding tumor initiation and progression, as well as for potential use as diagnostic, prognostic, and therapeutic indicators.

JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY (2021)

Add to Collection
Article Medicine, Research & Experimental

Tracheal Resection in the Management of Thyroid Cancer: AnEvidence-BasedApproach

Meredith Allen et al.

Summary: This study aimed to determine the impact of patient demographics and surgical approach on patient outcomes after tracheal resection in thyroid cancer management. The systematic review and meta-analysis revealed that the surgical approach and patient demographics play a significant role in postoperative complications and outcomes.

LARYNGOSCOPE (2021)

Add to Collection
Article Endocrinology & Metabolism

Advanced thyroid carcinomas: neural network analysis of ultrasonographic characteristics

Michael Cordes et al.

Summary: This study found that advanced thyroid carcinomas exhibit distinct clinical and sonographic characteristics, including higher age and male patients, as well as larger and irregularly shaped tumors. The neural network showed a high accuracy in discriminating advanced from non-advanced tumors, suggesting its potential utility in classifying thyroid malignancies. Further prospective investigations with larger patient cohorts are needed to validate these findings.

THYROID RESEARCH (2021)

Add to Collection
Article Oncology

Vitamin C sensitizes BRAFV600E thyroid cancer to PLX4032 via inhibiting the feedback activation of MAPK/ERK signal by PLX4032

Xi Su et al.

Summary: Combination therapy of PLX4032 and Vitamin C significantly inhibits proliferation and tumor growth of BRAF(MT) thyroid cancer cells, inducing cell apoptosis and cell cycle arrest. The therapy relieves the pathway feedback activation caused by PLX4032 monotherapy.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)

Add to Collection
Article Pathology

Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features

James M. Dolezal et al.

Summary: Deep learning prediction of the BRAF-RAS gene expression spectrum can aid in distinguishing indolent NIFTP from PTCs, by detecting histologic features associated with the spectrum.

MODERN PATHOLOGY (2021)

Add to Collection
Article Oncology

Prevalence of cancer and the benign call rate of afirma gene classifier in 18F-Fluorodeoxyglucose positron emission tomography positive cytologically indeterminate thyroid nodules

Mayumi Endo et al.

Summary: The study aimed to investigate the cancer risk of PET-positive ITNs and the benign call rate of Afirma gene classifier in these cases. Results showed a higher BCR with Afirma GSC-tested ITNs and a higher BCR in ITNs with low-risk sonographic pattern.

CANCER MEDICINE (2021)

Add to Collection
Article Oncology

High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS

Menghui Li et al.

Summary: The study demonstrated the importance of the modified TI-RADS report system in distinguishing malignant and benign thyroid nodules, especially in managing high-risk nodules. Changes in nodule grade status were mainly observed in grades 4a and above over a 5-year follow-up period, with higher grades indicating more malignant progression.

CANCER MANAGEMENT AND RESEARCH (2021)

Add to Collection
Article Surgery

Clinical and pathologic features for predicting malignancy in thyroid follicular neoplasms

Kwangsoon Kim et al.

Summary: The prevalence of malignancy in patients with a preoperative diagnosis of follicular neoplasm was higher in this study than in previous reports. PTC-related nuclear changes serve as a useful predictor for diagnosing malignancy. Further studies are needed to confirm these results.

GLAND SURGERY (2021)

Add to Collection
Article Endocrinology & Metabolism

Bone metastasis from noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP); a case report

Yasaman Fakhar et al.

Summary: This case report highlights the rare occurrence of distant metastasis in NIFTP and emphasizes the importance of individualized analysis and ongoing post-operative follow-up for detection of residual or recurrent disease.

BMC ENDOCRINE DISORDERS (2021)

Add to Collection
Review Endocrinology & Metabolism

Levothyroxine Therapy in Thyrodectomized Patients

Paolo Miccoli et al.

Summary: Administration of the optimal dose of levothyroxine is crucial after total thyroidectomy to avoid hypothyroidism or thyrotoxicosis. Most methods rely on thyroid function test results and patient symptoms for dose adjustments. Factors beyond body weight may also play a role in determining the proper dose of LT4.

FRONTIERS IN ENDOCRINOLOGY (2021)

Add to Collection
Article Multidisciplinary Sciences

Diagnosing thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance cytology with the deep convolutional neural network

Inyoung Youn et al.

Summary: The study compared the diagnostic performances of physicians and a deep convolutional neural network in predicting malignancy with ultrasound images of thyroid nodules with AUS/FLUS cytology. The results showed that for thyroid nodules with AUS/FLUS cytology, the diagnostic performance of the CNN was comparable to that of physicians with varying experience levels.

SCIENTIFIC REPORTS (2021)

Add to Collection
Article Oncology

Artificial intelligence for clinical oncology

Benjamin H. Kann et al.

Summary: This article discusses the challenges faced in clinical oncology, proposes a pathway for narrow-task AI applications in clinical cancer care, and emphasizes the importance of clinical validity, utility, and usability.

CANCER CELL (2021)

Add to Collection
Article Biotechnology & Applied Microbiology

The prognostic value of plasma complement factor B (CFB) in thyroid carcinoma

Pu Wu et al.

Summary: The study found that plasma complement factor B (CFB) is significantly associated with the development and prognosis of papillary thyroid carcinoma (PTC), mainly enriched in immune response pathways. The expression level of CFB is related to the infiltration of different types of immune cells in the tumor microenvironment.

BIOENGINEERED (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Cancer-Associated Adipocytes in Breast Cancer: Causes and Consequences

Ilona Rybinska et al.

Summary: Breast cancer progression is heavily influenced by the interaction between tumor cells and cancer-associated adipocytes (CAAs), and understanding the molecular pathways related to adipocyte differentiation is crucial for devising new therapeutic interventions. Recent studies have highlighted the mechanisms through which CAAs impact breast cancer progression, including adipokine regulation, metabolic reprogramming, extracellular matrix remodeling, and immune cell modulation.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Thyroid Cancers: From Surgery to Current and Future Systemic Therapies through Their Molecular Identities

Loredana Lorusso et al.

Summary: Differentiated and undifferentiated thyroid cancers require different treatment approaches, with targeted therapies like TKIs showing efficacy. Systemic treatments for advanced cases are becoming more targeted based on the molecular identity of the tumor.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Article Oncology

Pan-Genomic Sequencing Reveals Actionable CDKN2A/2B Deletions and Kataegis in Anaplastic Thyroid Carcinoma

Adam Stenman et al.

Summary: Anaplastic thyroid carcinoma is a deadly tumor with limited treatment options once it spreads. Research found genetic abnormalities in the patients that may respond to CDK inhibitors, as well as a phenomenon called kataegis, which could be therapeutically relevant.

CANCERS (2021)

Add to Collection
Article Biochemistry & Molecular Biology

Using Deep Convolutional Neural Networks for Enhanced Ultrasonographic Image Diagnosis of Differentiated Thyroid Cancer

Wai-Kin Chan et al.

Summary: The study demonstrated that deep convolutional neural networks (CNNs) showed good performance in diagnosing thyroid cancer, with CNNs performing better than physicians in classifying malignant and benign thyroid tumors. Retrained CNNs improved diagnostic accuracy in most DTC patients.

BIOMEDICINES (2021)

Add to Collection
Article Endocrinology & Metabolism

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer American Thyroid Association Anaplastic Thyroid Cancer Guidelines Task Force

Keith C. Bible et al.

Summary: The guidelines for the management of anaplastic thyroid cancer (ATC) aim to provide evidence-based recommendations to inform clinical decision-making, encompassing diagnosis, treatment goals, locoregional and advanced disease approaches, palliative care, surveillance, and ethical considerations.

THYROID (2021)

Add to Collection
Review Radiology, Nuclear Medicine & Medical Imaging

PET/CT in the management of differentiated thyroid cancer

Emilia Zampella et al.

Summary: The standard treatment for differentiated thyroid cancer usually involves surgery and iodine-131 treatment, with follow-up including monitoring of serum thyroglobulin levels, neck ultrasound, and whole-body scans. PET/CT plays a crucial role in evaluating patients, especially high-risk and metastatic cases.

DIAGNOSTIC AND INTERVENTIONAL IMAGING (2021)

Add to Collection
Review Oncology

Radiomics in Differentiated Thyroid Cancer and Nodules: Explorations, Application, and Limitations

Yuan Cao et al.

Summary: Differentiated thyroid cancer (DTC) is the most common endocrine malignancy with a high incidence rate in females. The COVID-19 epidemic has increased the risk of treatment delay, leading to increased morbidity and mortality rates of DTC. Radiomics, as an emerging technique, allows for the quantitative extraction of high-throughput features from medical images and may improve clinical decision-making for DTC patients.

CANCERS (2021)

Add to Collection
Review Cell Biology

The Genomic Landscape of Thyroid Cancer Tumourigenesis and Implications for Immunotherapy

Amandeep Singh et al.

Summary: Thyroid cancer, including differentiated and aggressive variants, can be better understood and targeted through next-generation sequencing and advanced data analysis, potentially leading to improved treatment options like immunotherapy. Understanding the genetic aberrations involved in thyroid cancer development and progression is crucial for developing effective therapeutic strategies.

CELLS (2021)

Add to Collection
Review Oncology

Thyroid cancer, recent advances in diagnosis and therapy

Fadi Nabhan et al.

Summary: The diagnosis and management of patients with follicular cell-derived thyroid cancer has evolved to be more personalized over recent decades, with advancements in molecular technologies enabling tailored treatment options for patients with more aggressive forms of the disease. Guidelines from various societies worldwide emphasize the importance of an individualized approach to clinical management in this field.

INTERNATIONAL JOURNAL OF CANCER (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Opportunities and Challenges of Liquid Biopsy in Thyroid Cancer

Chiara Romano et al.

Summary: Liquid biopsy is a non-invasive approach that can detect and analyze biological samples released from tumors into the bloodstream, providing valuable molecular information for defining diagnosis, estimating prognosis, and monitoring tumor recurrence or treatment response.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Article Endocrinology & Metabolism

Risk stratification in differentiated thyroid cancer with RAI-avid lung metastases

Keiko Ohkuwa et al.

Summary: The study revealed that factors such as age ≥55 years, follicular carcinoma, lung metastasis tumor ≥ 10mm in diameter, and NLR ≥ 2.6 can lead to decreased cause-specific survival in DTC patients with RAI-accumulating lung metastasis. Multivariate analysis identified lung metastatic tumor size ≥10mm and NLR ≥ 2.6 as independent prognostic factors. Patients in the high-risk group with both factors had significantly poorer survival rates, suggesting they may benefit from tyrosine kinase inhibitor therapy in the future.

ENDOCRINE CONNECTIONS (2021)

Add to Collection
Review Oncology

Current Management of Bone Metastases from Differentiated Thyroid Cancer

Satoshi Kato et al.

Summary: Patients with bone metastases from differentiated thyroid carcinoma have better prognosis compared to other cancers, especially with advanced local treatments like surgery, radiotherapy, and percutaneous procedures. Achieving long-term control of thyroid BMs is desired, especially in patients with a single metastasis or oligometastases, to improve quality of life and survival rates. Recent advancements in local therapies offer potential for better long-term tumor control and prognosis.

CANCERS (2021)

Add to Collection
Article Oncology

The Role of Vitamin D as a Prognostic Marker in Papillary Thyroid Cancer

Ashank Bains et al.

Summary: Thyroid cancer is the most common endocrine malignancy in the United States, with papillary thyroid cancer as the most common subtype. Despite controversial debates, the potential role of vitamin D in cancer-related pathways and its significance as a prognostic marker in papillary thyroid cancer has gained attention. Previous literature has highlighted the anti-proliferative, anti-inflammatory, and pro-differentiation effects of vitamin D in various cancers, while ongoing studies aim to establish a definitive link between vitamin D status and papillary thyroid carcinoma.

CANCERS (2021)

Add to Collection
Review Oncology

Translational Utility of Liquid Biopsies in Thyroid Cancer Management

Ayanthi A. Wijewardene et al.

Summary: Liquid biopsies are a novel technique that assess for circulating tumor cells (CTC), circulating tumor DNA (ctDNA), and microRNA in peripheral blood samples of cancer patients. The diagnostic role of liquid biopsy in oncology has expanded in recent years, especially in lung, colorectal, and breast cancer. In thyroid cancer, liquid biopsy's role in diagnosis or prognosis is transitioning from the lab to clinical practice.

CANCERS (2021)

Add to Collection
Review Health Care Sciences & Services

Digital Twins: From Personalised Medicine to Precision Public Health

Maged N. Kamel Boulos et al.

Summary: A digital twin is a virtual model of a physical entity, increasingly used in various industry sectors. In the fields of medicine and public health, digital twin technology can drive radical transformation towards precision medicine and personalized treatments. Digital twins enable learning, discovering new knowledge, and hypothesis generation, while also playing a key role in formulating highly personalized treatments and interventions.

JOURNAL OF PERSONALIZED MEDICINE (2021)

Add to Collection
Article Medicine, General & Internal

Usefulness of pre-thyroidectomy neutrophil-lymphocyte, platelet-lymphocyte, and monocyte-lymphocyte ratios for discriminating lymph node and distant metastases in differentiated thyroid cancer

Cinthia Minatel Riguetto et al.

Summary: The study focused on examining the relationships of NLR, PLR, and MLR with clinicopathological characteristics of patients with differentiated thyroid cancer. PLR was higher in patients with distant metastasis, while MLR was associated with active disease. Cut-off values of NLR, PLR, and MLR were able to differentiate distant metastasis from lymph node metastasis with good sensitivity and accuracy.

CLINICS (2021)

Add to Collection
Article Public, Environmental & Occupational Health

Artificial Intelligence (AI) in medicine as a strategic valuable tool

Andreas Larentzakis et al.

Summary: Human creativity has led to the creation of machines that surpass human capabilities in workload, efficiency, precision, endurance, strength, and repetitiveness. Artificial intelligence aims to mimic human intelligence and critical thinking, playing a central role in the field of healthcare.

PAN AFRICAN MEDICAL JOURNAL (2021)

Add to Collection
Review Endocrinology & Metabolism

Malignancy risk of hyperfunctioning thyroid nodules compared with non-toxic nodules: systematic review and a meta-analysis

Lorraine W. Lau et al.

Summary: Hot nodules have a lower risk of malignancy compared to non-toxic nodules, but the incidence of malignancy in hot nodules was higher than expected, highlighting the need for further research.

THYROID RESEARCH (2021)

Add to Collection
Article Oncology

A study of 17 cases for the identification of prognostic factors for anaplastic thyroid carcinoma

Takashi Masui et al.

Summary: Anaplastic thyroid cancer (ATC) has a poor prognosis with no established treatment protocols. Factors indicating longer survival in patients under 70 years old include absence of distant metastasis and treatment by radical resection. Tumor size and white blood cell count were not associated with ATC prognosis in the studied cohort, and tracheostomy did not contribute to improved prognosis. Prognostic factors like these are crucial for clinicians in determining appropriate treatment strategies for ATC patients.

MOLECULAR AND CLINICAL ONCOLOGY (2021)

Add to Collection
Review Pathology

Artificial Intelligence in Thyroid Fine Needle Aspiration Biopsies

Brie Kezlarian et al.

Summary: The review summarizes the application of AI technology to thyroid cytopathology, tracing the evolution from morphometric analysis to convolutional neural networks. It explores various applications of AI, such as distinguishing different types of thyroid nodules, and highlights the potential for future advancements in cytopathology practice through AI technology.

ACTA CYTOLOGICA (2021)

Add to Collection
Article Surgery

Ultrasonographic features for differentiating follicular thyroid carcinoma and follicular adenoma

Ting-Chun Kuo et al.

ASIAN JOURNAL OF SURGERY (2020)

Add to Collection
Article Oncology

Application of a machine learning algorithm to predict malignancy in thyroid cytopathology

Danielle D. Elliott Range et al.

CANCER CYTOPATHOLOGY (2020)

Add to Collection
Review Oncology

Artificial intelligence in oncology

Hideyuki Shimizu et al.

CANCER SCIENCE (2020)

Add to Collection
Review Ecology

Big data in digital healthcare: lessons learnt and recommendations for general practice

Raag Agrawal et al.

HEREDITY (2020)

Add to Collection
Review Endocrinology & Metabolism

Updates on the Management of Thyroid Cancer

Katherine A. Araque et al.

HORMONE AND METABOLIC RESEARCH (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Multikinase Inhibitor Treatment in Thyroid Cancer

Ole Vincent Ancker et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Cell Biology

Impact of image analysis and artificial intelligence in thyroid pathology, with particular reference to cytological aspects

Ilaria Girolami et al.

CYTOPATHOLOGY (2020)

Add to Collection
Review Biochemistry & Molecular Biology

The Impact of Transcription Factor Prospero Homeobox 1 on the Regulation of Thyroid Cancer Malignancy

Magdalena Rudzinska et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Chemistry, Analytical

Ultrasound Image-Based Diagnosis of Malignant Thyroid Nodule Using Artificial Intelligence

Dat Tien Nguyen et al.

SENSORS (2020)

Add to Collection
Article Environmental Sciences

Network-Based Genetic Profiling Reveals Cellular Pathway Differences Between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma

Md. Ali Hossain et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Add to Collection
Review Endocrinology & Metabolism

Update on Fundamental Mechanisms of Thyroid Cancer

Alessandro Prete et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection
Review Endocrinology & Metabolism

New Therapies for Advanced Thyroid Cancer

Diprajan Laha et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection
Review Radiology, Nuclear Medicine & Medical Imaging

Radioactive Iodine Therapy in Differentiated Thyroid Cancer: 2020 Update

Anthony Ciarallo et al.

AMERICAN JOURNAL OF ROENTGENOLOGY (2020)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

Comparison of thyroid hormone withdrawal and recombinant human thyroid-stimulating hormone administration for adjuvant therapy in patients with intermediate- to high-risk differentiated thyroid cancer

Yusuke Iizuka et al.

ANNALS OF NUCLEAR MEDICINE (2020)

Add to Collection
Article Endocrinology & Metabolism

Transcription Factor Profiling Identifies Spatially Heterogenous Mediators of Follicular Thyroid Cancer Invasion

Norman G. Nicolson et al.

ENDOCRINE PATHOLOGY (2020)

Add to Collection
Article Medicine, General & Internal

Thyroid Cancer Incidence in Bulgaria before and after the Introduction of Universal Salt Iodization: An Analysis of the National Cancer Registry Data

Ludmila Borislavova Ivanova et al.

BALKAN MEDICAL JOURNAL (2020)

Add to Collection
Article Oncology

A Clinical Assessment of an Ultrasound Computer-Aided Diagnosis System in Differentiating Thyroid Nodules With Radiologists of Different Diagnostic Experience

Yichun Zhang et al.

FRONTIERS IN ONCOLOGY (2020)

Add to Collection
Article Multidisciplinary Sciences

Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

Motoyasu Saji et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Article Oncology

Digital gene expression analysis might aid in the diagnosis of thyroid cancer

H. Armanious et al.

CURRENT ONCOLOGY (2020)

Add to Collection
Article Endocrinology & Metabolism

Distribution and Prognostic Significance of Estrogen Receptor α (ERα), Estrogen Receptor β (ERβ), and Human Epidermal Growth Factor Receptor 2 (HER-2) in Thyroid Carcinoma

Anjali Mishra et al.

JOURNAL OF THYROID RESEARCH (2020)

Add to Collection
Review Endocrinology & Metabolism

Progression and dormancy in metastatic thyroid cancer: concepts and clinical implications

Neel Rajan et al.

ENDOCRINE (2020)

Add to Collection
Review Endocrinology & Metabolism

Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers

Scong-Keun Yoo et al.

ENDOCRINOLOGY AND METABOLISM (2020)

Add to Collection
Review Medicine, General & Internal

Ultrasound Classification of Thyroid Nodules: A Systematic Review

Rakesh Mistry et al.

CUREUS JOURNAL OF MEDICAL SCIENCE (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Artificial intelligence (AI) and big data in cancer and precision oncology

Zodwa Dlamini et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)

Add to Collection
Article Pediatrics

Surgical management of follicular thyroid carcinoma in children and adolescents: A study of 30 cases

Claudio Spinelli et al.

JOURNAL OF PEDIATRIC SURGERY (2019)

Add to Collection
Article Surgery

Introduction to artificial intelligence in medicine

Yoav Mintz et al.

MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES (2019)

Add to Collection
Review Biochemistry & Molecular Biology

Clinical validity of saliva and novel technology for cancer detection

Karolina Elzbieta Kaczor-Urbanowicz et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

Add to Collection
Article Oncology

PI3K/mTOR inhibition potentiates and extends palbociclib activity in anaplastic thyroid cancer

Kristen Wong et al.

ENDOCRINE-RELATED CANCER (2019)

Add to Collection
Review Pathology

Pathology Image Analysis Using Segmentation Deep Learning Algorithms

Shidan Wang et al.

AMERICAN JOURNAL OF PATHOLOGY (2019)

Add to Collection
Review Surgery

Radioisotope imaging for discriminating benign from malignant cytologically indeterminate thyroid nodules

Olivier Rager et al.

GLAND SURGERY (2019)

Add to Collection
Article Oncology

Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

S. Filetti et al.

ANNALS OF ONCOLOGY (2019)

Add to Collection
Article Oncology

A computer-aided diagnosing system in the evaluation of thyroid nodules-experience in a specialized thyroid center

Shujun Xia et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2019)

Add to Collection
Review Endocrinology & Metabolism

Advances in metabolomics of thyroid cancer diagnosis and metabolic regulation

Raziyeh Abooshahab et al.

ENDOCRINE (2019)

Add to Collection
Article Endocrinology & Metabolism

Expression and clinicopathological role of miR146a in thyroid follicular carcinoma

Elisa Pignatti et al.

ENDOCRINE (2019)

Add to Collection
Article Biotechnology & Applied Microbiology

Expression of long non-coding RNA H19 predicts distant metastasis in minimally invasive follicular thyroid carcinoma

Yan Dai et al.

BIOENGINEERED (2019)

Add to Collection
Review Endocrinology & Metabolism

Medical Big Data Is Not Yet Available: Why We Need Realism Rather than Exaggeration

Hun-Sung Kim et al.

ENDOCRINOLOGY AND METABOLISM (2019)

Add to Collection
Review Oncology

Long Non-Coding RNAs in Thyroid Cancer: Implications for Pathogenesis, Diagnosis, and Therapy

Mohammad-Reza Mahmoudian-Sani et al.

ONCOLOGY RESEARCH AND TREATMENT (2019)

Add to Collection
Article Oncology

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers

Nikita Pozdeyev et al.

CLINICAL CANCER RESEARCH (2018)

Add to Collection
Review Biochemistry & Molecular Biology

Novel targeted therapies and immunotherapy for advanced thyroid cancers

George E. Naoum et al.

MOLECULAR CANCER (2018)

Add to Collection
Article Cell Biology

Heterogeneity of Thyroid Cancer

Ewa Chmielik et al.

PATHOBIOLOGY (2018)

Add to Collection
Article Endocrinology & Metabolism

Comparing the Prognostic Value of the Eighth Edition of the American Joint Committee on Cancer/Tumor Node Metastasis Staging System Between Papillary and Follicular Thyroid Cancer

Evert F. S. van Velsen et al.

THYROID (2018)

Add to Collection
Article Oncology

Racial disparities of differentiated thyroid carcinoma: clinical behavior, treatments, and long-term outcomes

Jianing Tang et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2018)

Add to Collection
Article Surgery

Outcomes and prognostic factors in thyroid cancer patients with cranial metastases: A retrospective cohort study of 4,683 patients

Yi-Wen Hong et al.

INTERNATIONAL JOURNAL OF SURGERY (2018)

Add to Collection
Review Endocrinology & Metabolism

Follicular thyroid cancer and Hurthle cell carcinoma: challenges in diagnosis, treatment, and clinical management

Giorgio Grani et al.

LANCET DIABETES & ENDOCRINOLOGY (2018)

Add to Collection
Article Endocrinology & Metabolism

Role of Chemokines in Thyroid Cancer Microenvironment: is CXCL8 the Main Player?

Mario Rotondi et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Add to Collection
Article Endocrinology & Metabolism

A six-gene panel to label follicular adenoma, low- and high-risk follicular thyroid carcinoma

Anello Marcello Poma et al.

ENDOCRINE CONNECTIONS (2018)

Add to Collection
Review Radiology, Nuclear Medicine & Medical Imaging

Differentiated thyroid cancer theranostics: radioiodine and beyond

Partha S. Choudhury et al.

BRITISH JOURNAL OF RADIOLOGY (2018)

Add to Collection
Article Oncology

Neck Ultrasound in Patients with Follicular Thyroid Carcinoma

Konstantinos Segkos et al.

HORMONES & CANCER (2018)

Add to Collection
Article Medical Laboratory Technology

Artificial neural network model to distinguish follicular adenoma from follicular carcinoma on fine needle aspiration of thyroid

Rajiv Savala et al.

DIAGNOSTIC CYTOPATHOLOGY (2018)

Add to Collection
Article Medicine, General & Internal

Thyroid follicular carcinoma in a teenager: A case report

Kosuke Oka et al.

JOURNAL OF GENERAL AND FAMILY MEDICINE (2018)

Add to Collection
Article Endocrinology & Metabolism

Should subcentimeter non-invasive encapsulated, follicular variant of papillary thyroid carcinoma be included in the noninvasive follicular thyroid neoplasm with papillary-like nuclear features category?

Bin Xu et al.

ENDOCRINE (2018)

Add to Collection
Review Oncology

Thyroid nodules and cancer management guidelines: comparisons and controversies

Fadi Nabhan et al.

ENDOCRINE-RELATED CANCER (2017)

Add to Collection
Review Endocrinology & Metabolism

The History of the Follicular Variant of Papillary Thyroid Carcinoma

Giovanni Tallini et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)

Add to Collection
Review Biochemistry & Molecular Biology

Current Advances in Thyroid Cancer Management. Are We Ready for the Epidemic Rise of Diagnoses?

Dagmara Rusinek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Add to Collection
Review Biochemistry & Molecular Biology

Differentiated Thyroid Cancer-Treatment: State of the Art

Benedikt Schmidbauer et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Add to Collection
Article Cell Biology

GPER/ERK&B pathway is involved in cadmium-induced proliferation, invasion and migration of GPER-positive thyroid cancer cells

Ping Zhu et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)

Add to Collection
Article Endocrinology & Metabolism

Defining Radioiodine-Refractory Differentiated Thyroid Cancer: Efficacy and Safety of Lenvatinib by Radioiodine-Refractory Criteria in the SELECT Trial

Naomi Kiyota et al.

THYROID (2017)

Add to Collection
Article Endocrinology & Metabolism

Estimation of Second Primary Cancer Risk After Treatment with Radioactive Iodine for Differentiated Thyroid Carcinoma

Nilton Lavatori Correa et al.

THYROID (2017)

Add to Collection
Article Endocrinology & Metabolism

The 2017 Bethesda System for Reporting Thyroid Cytopathology

Edmund S. Cibas et al.

THYROID (2017)

Add to Collection
Article

Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution

Geneviève Dom et al.

Oncotarget (2017)

Add to Collection
Article Multidisciplinary Sciences

Differentiating malignant from benign thyroid nodules with indeterminate cytology by 99mTc-MIBI scan: a new quantitative method for improving diagnostic accuracy

A. Campenni et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Article Surgery

Comparison of prognostic scoring systems in follicular thyroid cancer

K. W. Teo et al.

ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND (2017)

Add to Collection
Article Surgery

Patterns of metastasis in follicular thyroid carcinoma and the difference between early and delayed presentation

R. Parameswaran et al.

ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND (2017)

Add to Collection
Article Multidisciplinary Sciences

Long-term follow-up of papillary and follicular thyroid carcinomas with bone metastasis

Jen-Der Lin et al.

PLoS One (2017)

Add to Collection
Review Endocrinology & Metabolism

Epigenetic modulators of thyroid cancer

Sandra Rodriguez-Rodero et al.

ENDOCRINOLOGIA DIABETES Y NUTRICION (2017)

Add to Collection
Review Endocrinology & Metabolism

Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma-A meta-analysis

Huy Gia Vuong et al.

CLINICAL ENDOCRINOLOGY (2017)

Add to Collection
Article Oncology

Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence

Tihana Ibrahimpasic et al.

CLINICAL CANCER RESEARCH (2017)

Add to Collection
Review Medicine, Research & Experimental

Hepatocyte Growth Factor/C-Met Axis in Thyroid Cancer: From Diagnostic Biomarker to Therapeutic Target

Maria Trovato et al.

BIOMARKER INSIGHTS (2017)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

[18F]FDG PET/CT outperforms [18F]FDG PET/MRI in differentiated thyroid cancer

Alexis Vrachimis et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2016)

Add to Collection
Article Medicine, Research & Experimental

Comparative Evaluation of β-Catenin and E-Cadherin Expression in Liquid Aspiration Biopsy Specimens of Thyroid Nodules

A. V. Isaeva et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2016)

Add to Collection
Article Oncology

Iodine deficiency and thyroid cancer trends in three regions of Thailand, 1990-2009

Susanna D. Mitro et al.

CANCER EPIDEMIOLOGY (2016)

Add to Collection
Review Cell Biology

Molecular Markers Involved in Tumorigenesis of Thyroid Carcinoma: Focus on Aggressive Histotypes

Gustavo C. Penna et al.

CYTOGENETIC AND GENOME RESEARCH (2016)

Add to Collection
Article Medicine, Research & Experimental

Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

Inigo Lancia et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Add to Collection
Editorial Material Computer Science, Artificial Intelligence

Image analysis and machine learning in digital pathology: Challenges and opportunities

Anant Madabhushi et al.

MEDICAL IMAGE ANALYSIS (2016)

Add to Collection
Article Cell Biology

Somatic mutation profiling of follicular thyroid cancer by next generation sequencing

Michal Swierniak et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)

Add to Collection
Article Endocrinology & Metabolism

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer

Bryan R. Haugen et al.

THYROID (2016)

Add to Collection
Article Surgery

Prognosis After Brain Metastasis from Differentiated Thyroid Carcinoma

Fumi Saito et al.

WORLD JOURNAL OF SURGERY (2016)

Add to Collection
Review Biotechnology & Applied Microbiology

Hurthle cell carcinoma: current perspectives

Sara Ahmadi et al.

ONCOTARGETS AND THERAPY (2016)

Add to Collection
Article Cell Biology

Histone Modifications and Cancer

James E. Audia et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Add to Collection
Article Oncology

Genetic alterations of differentiated thyroid carcinoma in iodine-rich and iodine-deficient countries

Huy Gia Vuong et al.

CANCER MEDICINE (2016)

Add to Collection
Review Medicine, General & Internal

Cytopathologic diagnosis of fine needle aspiration biopsies of thyroid nodules

Evangelos P. Misiakos et al.

WORLD JOURNAL OF CLINICAL CASES (2016)

Add to Collection
Article Multidisciplinary Sciences

The Largest Known Survival Analysis of Patients with Brain Metastasis from Thyroid Cancer Based on Prognostic Groups

Jinhyun Choi et al.

PLOS ONE (2016)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

Diffusion-weighted MRI and apparent diffusion coefficient in differentiation of benign from malignant solitary thyroid nodule

Hossam M. Abdel-Rahman et al.

EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE (2016)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

Risk for malignancy of thyroid nodules: Comparative study between TIRADS and US based classification system

Germeen Albair Ashamallah et al.

EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE (2016)

Add to Collection
Article Oncology

Genes and pathways identified in thyroid carcinoma based on bioinformatics analysis

J. W. Yu et al.

NEOPLASMA (2016)

Add to Collection
Review Pathology

Pathobiology of MicroRNAs and Their Emerging Role in Thyroid Fine-Needle Aspiration

Marie Ludvikova et al.

ACTA CYTOLOGICA (2015)

Add to Collection
Article Endocrinology & Metabolism

Mutations of TSHR and TP53 Genes in an Aggressive Clear Cell Follicular Carcinoma of the Thyroid

Guo-Xia Tong et al.

ENDOCRINE PATHOLOGY (2015)

Add to Collection
Article Endocrinology & Metabolism

Reassessing the NTCTCS Staging Systems for Differentiated Thyroid Cancer, Including Age at Diagnosis

Donald S. A. McLeod et al.

THYROID (2015)

Add to Collection
Article Endocrinology & Metabolism

Follicular Thyroid Carcinoma: How Have Histologic Diagnoses Changed in the Last Half-Century and What Are the Prognostic Implications?

Nicole A. Cipriani et al.

THYROID (2015)

Add to Collection
Article Oncology

Follicular thyroid carcinoma: differences in clinical relevance between minimally invasive and widely invasive tumors

Mauro Podda et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2015)

Add to Collection
Review Endocrinology & Metabolism

Molecular Targeted Therapies of Aggressive Thyroid Cancer

Silvia Martina Ferrari et al.

FRONTIERS IN ENDOCRINOLOGY (2015)

Add to Collection
Article Oncology

Lymph Node Metastases do not Impact Survival in Follicular Variant Papillary Thyroid Cancer

David F. Schneider et al.

ANNALS OF SURGICAL ONCOLOGY (2015)

Add to Collection
Article Surgery

Follicular variant papillary thyroid carcinoma with a twist

Obinna Nwaeze et al.

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS (2015)

Add to Collection
Review Endocrinology & Metabolism

Iodine intake as a risk factor for thyroid cancer: a comprehensive review of animal and human studies

Michael B. Zimmermann et al.

THYROID RESEARCH (2015)

Add to Collection
Article Otorhinolaryngology

Comparison of Survival Rates Between Papillary and Follicular Thyroid Carcinomas Among 36,725 Patients

Sam L. Oyer et al.

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY (2014)

Add to Collection
Review Oncology

New insights in risk stratification of differentiated thyroid cancer

Maria Papaleontiou et al.

CURRENT OPINION IN ONCOLOGY (2014)

Add to Collection
Article Endocrinology & Metabolism

Follicular thyroid carcinoma with distant metastasis: outcome and prognostic factor

Kiminori Sugino et al.

ENDOCRINE JOURNAL (2014)

Add to Collection
Article Endocrinology & Metabolism

Follicular Variant of Papillary Thyroid Carcinoma: Accuracy of FNA Diagnosis and Implications for Patient Management

Berrin Ustun et al.

ENDOCRINE PATHOLOGY (2014)

Add to Collection
Review Surgery

Classification of aerodigestive tract invasion from thyroid cancer

Michael Brauckhoff

LANGENBECKS ARCHIVES OF SURGERY (2014)

Add to Collection
Review Radiology, Nuclear Medicine & Medical Imaging

Adverse effects of radioactive iodine-131 treatment for differentiated thyroid carcinoma

Armaghan Fard-Esfahani et al.

NUCLEAR MEDICINE COMMUNICATIONS (2014)

Add to Collection
Article Multidisciplinary Sciences

Actual Incidence and Clinical Behaviour of Follicular Thyroid Carcinoma: An Institutional Experience

Carmela De Crea et al.

SCIENTIFIC WORLD JOURNAL (2014)

Add to Collection
Editorial Material Medicine, General & Internal

Clinical implications of follicular and Hurthle cell carcinoma in an iodine-sufficient area

Dong Yeob Shin et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2014)

Add to Collection
Article Surgery

Unusual presentation of follicular carcinoma thyroid with special emphasis on their management

Sangram Keshari Panda et al.

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS (2014)

Add to Collection
Review Radiology, Nuclear Medicine & Medical Imaging

Ultrasound elastography for thyroid nodules: recent advances

Jin Young Kwak et al.

ULTRASONOGRAPHY (2014)

Add to Collection
Article Endocrinology & Metabolism

Therapeutic strategy for low-risk thyroid cancer in Kanaji Thyroid Hospital [Review]

Makoto Kammori et al.

ENDOCRINE JOURNAL (2013)

Add to Collection
Article Multidisciplinary Sciences

Utility of a Histone Deacetylase Inhibitor (PXD101) for Thyroid Cancer Treatment

Shu-Fu Lin et al.

PLOS ONE (2013)

Add to Collection
Article Endocrinology & Metabolism

Molecular Genotyping of Follicular Variant of Papillary Thyroid Carcinoma Correlates with Diagnostic Category of Fine-Needle Aspiration Cytology: Values of RAS Mutation Testing

Sang Ryung Lee et al.

THYROID (2013)

Add to Collection
Article Endocrinology & Metabolism

Thyroid Lobectomy Is Associated with Excellent Clinical Outcomes in Properly Selected Differentiated Thyroid Cancer Patients with Primary Tumors Greater Than 1 cm

Fernanda Vaisman et al.

JOURNAL OF THYROID RESEARCH (2013)

Add to Collection
Article Endocrinology & Metabolism

Mixed Medullary-Follicular Carcinoma of the Thyroid

Maasumeh Tohidi et al.

CASE REPORTS IN ENDOCRINOLOGY (2013)

Add to Collection
Review Pathology

Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer

Kennichi Kakudo et al.

PATHOLOGY INTERNATIONAL (2012)

Add to Collection
Article Biology

Follow-up of patients treated with retinoic acid for the control of radioiodine non-responsive advanced thyroid carcinoma

S. M. Coelho et al.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2011)

Add to Collection
Article Pathology

Follicular thyroid carcinoma

Manuel Sobrinho-Simoes et al.

MODERN PATHOLOGY (2011)

Add to Collection
Article Radiology, Nuclear Medicine & Medical Imaging

Thyroid Imaging Reporting and Data System for US Features of Nodules : A Step in Establishing Better Stratification of Cancer Risk

Jin Young Kwak et al.

RADIOLOGY (2011)

Add to Collection
Review Endocrinology & Metabolism

Thyroid Carcinoma in Children and Adolescents-Systematic Review of the Literature

Fernanda Vaisman et al.

JOURNAL OF THYROID RESEARCH (2011)

Add to Collection
Review Pathology

Thyroid Cancer of Follicular Cell Origin in Inherited Tumor Syndromes

Vania Nose

ADVANCES IN ANATOMIC PATHOLOGY (2010)

Add to Collection
Review Pathology

Diagnostic Utility of Galectin-3 in Thyroid Cancer

Connie G. Chiu et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Add to Collection
Article Oncology

Complications of Radioactive Iodine Treatment of Thyroid Carcinoma

Stephanie L. Lee

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2010)

Add to Collection
Review Cell Biology

The PI3K-Akt-mTOR pathway in initiation and progression of thyroid tumors

Motoyasu Saji et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Add to Collection
Article Endocrinology & Metabolism

The Bethesda System for Reporting Thyroid Cytopathology

Edmund S. Cibas et al.

THYROID (2009)

Add to Collection
Review Surgery

A pathologic re-review of follicular thyroid neoplasms: The impact of changing the threshold for the diagnosis of the follicular variant of papillary thyroid carcinoma

Sandy Widder et al.

SURGERY (2008)

Add to Collection
Article Surgery

The impact of lymph node involvement on survival in patients with papillary and follicular thyroid carcinoma

Victor Zaydfudim et al.

SURGERY (2008)

Add to Collection
Article Endocrinology & Metabolism

Poorly differentiated follicular thyroid carcinoma: Prognostic factors and relevance of histological classification

Melania Pulcrano et al.

THYROID (2007)

Add to Collection
Article Medical Laboratory Technology

Follicular neoplasm of the thyroid - Vanishing cytologic diagnosis?

Umesh Kapur et al.

DIAGNOSTIC CYTOPATHOLOGY (2007)

Add to Collection
Article Oncology

Prognostic value of E-cadherin expression in thyroid follicular carcinoma

E Brecelj et al.

EJSO (2005)

Add to Collection
Article Pathology

Follicular carcinoma of the thyroid with hyperthyroidism - A case report

P Sharma et al.

ACTA CYTOLOGICA (2004)

Add to Collection
Article Endocrinology & Metabolism

Mixed medullary-follicular thyroid carcinoma - Report of a case and review of the literature

I Kostoglou-Athanassiou et al.

HORMONE RESEARCH (2004)

Add to Collection
Article Otorhinolaryngology

Differentiated thyroid carcinoma: Comparison between papillary and follicular carcinoma in a single institute

SM Chow et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2002)

Add to Collection
Article Surgery

Death from thyroid cancer of follicular cell origin

HS Wu et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2000)

Add to Collection
Article Pathology

Follicular lesions of the thyroid - W(h)ither follicular carcinoma?

RM DeMay

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2000)

Add to Collection
Article Pathology

Retinoblastoma expression in thyroid neoplasms

F Anwar et al.

MODERN PATHOLOGY (2000)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.