Recent advances in metal-, organo-, and biocatalyzed one-pot tandem reactions under environmentally responsible conditions

Because of their handedness and wide scope, transitionmetal-, organo-, and biocatalyzed tandem processes have become routine and highly sought-after methodologies because they dramatically increase synthetic efficiency, while decreasing the number of laboratory operations, the quantities of chemicals and solvents used, producing in a simpler way highly complex organic molecules with the desired selectivity. In this current opinion, recent examples of the use of metal-, organo-, and biocatalyzed tandem processes run under environmentally responsible conditions (e.g., use of water, biobased solvents, or without additional solvents) are showcased, highlighting practical and valuable aspects.

Automated summary

Due to their handedness and wide scope, transition-metal, organo-, and biocatalyzed tandem processes are routine and highly sought-after methods as they increase synthetic efficiency and simplify the production of complex organic molecules with desired selectivity by reducing the number of laboratory operations and the quantities of chemicals and solvents used.