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Flourishing tumor organoids: History, emerging technology, and application

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Organoids: An intermediate modeling platform in precision oncology

Ming-Zhu Jin et al.

CANCER LETTERS (2018)

Article Biochemistry & Molecular Biology

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs et al.

Article Biochemistry & Molecular Biology

Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer

Suk Hyung Lee et al.

Article Gastroenterology & Hepatology

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

Andrea Lampis et al.

GASTROENTEROLOGY (2018)

Article Multidisciplinary Sciences

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis et al.

SCIENCE (2018)

Review Oncology

Patient-derived tumor organoids for prediction of cancer treatment response

Peter W. Nagle et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Biotechnology & Applied Microbiology

Personalized Cancer Medicine: An Organoid Approach

Hamidreza Aboulkheyr Es et al.

TRENDS IN BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

Patient derived organoids to model rare prostate cancer phenotypes

Loredana Puca et al.

NATURE COMMUNICATIONS (2018)

Article Cell & Tissue Engineering

Use of bioreactors for culturing human retinal organoids improves photoreceptor yields

Patrick Ovando-Roche et al.

STEM CELL RESEARCH & THERAPY (2018)

Review Oncology

Organoid technology and applications in cancer research

Hanxiao Xu et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

Article Multidisciplinary Sciences

Intra-tumour diversification in colorectal cancer at the single-cell level

Sophie F. Roerink et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Organoid Modeling of the Tumor Immune Microenvironment

James T. Neal et al.

Review Biochemistry & Molecular Biology

Tissue-Engineered Grafts from Human Decellularized Extracellular Matrices: A Systematic Review and Future Perspectives

Andrea Porzionato et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemical Research Methods

Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells

Ryuji Morizane et al.

NATURE PROTOCOLS (2017)

Review Respiratory System

What is precision medicine?

Inke R. Koenig et al.

EUROPEAN RESPIRATORY JOURNAL (2017)

Article Immunology

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Daniel Ohlund et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Genetics & Heredity

Patient-derived xenografts undergo mouse-specific tumor evolution

Uri Ben-David et al.

NATURE GENETICS (2017)

Article Multidisciplinary Sciences

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids

Arianna Fumagalli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Oncology

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Chantal Pauli et al.

CANCER DISCOVERY (2017)

Article Multidisciplinary Sciences

High Shear Stresses under Exercise Condition Destroy Circulating Tumor Cells in a Microfluidic System

Sagar Regmi et al.

SCIENTIFIC REPORTS (2017)

Article Engineering, Biomedical

Bioprinted Osteogenic and Vasculogenic Patterns for Engineering 3D Bone Tissue

Batzaya Byambaa et al.

ADVANCED HEALTHCARE MATERIALS (2017)

Article Engineering, Biomedical

Direct 3D cell-printing of human skin with functional transwell system

Byoung Soo Kim et al.

BIOFABRICATION (2017)

Article Biochemistry & Molecular Biology

Systemic Immunity Is Required for Effective Cancer Immunotherapy

Matthew H. Spitzer et al.

Review Engineering, Biomedical

Current advances and future perspectives in extrusion-based bioprinting

Ibrahim T. Ozbolat et al.

BIOMATERIALS (2016)

Article Biochemistry & Molecular Biology

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors

Sergio Ruiz et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Designer matrices for intestinal stem cell and organoid culture

Nikolce Glorevski et al.

NATURE (2016)

Review Oncology

Microfluidics: A New Tool for Modeling Cancer-Immune Interactions

Alexandra Boussommier-Calleja et al.

TRENDS IN CANCER (2016)

Article Engineering, Biomedical

Towards artificial tissue models: past, present, and future of 3D bioprinting

Ahu Arslan-Yildiz et al.

BIOFABRICATION (2016)

Review Biochemistry & Molecular Biology

Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

Atul A. Chaudhari et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Oncology

Mouse models in oncoimmunology

Laurence Zitvogel et al.

NATURE REVIEWS CANCER (2016)

Article Engineering, Biomedical

3D printing of layered brain-like structures using peptide modified gellan gum substrates

Rodrigo Lozano et al.

BIOMATERIALS (2015)

Article Biochemistry & Molecular Biology

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch et al.

Article Biochemistry & Molecular Biology

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering et al.

Article Biochemistry & Molecular Biology

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj et al.

Article Gastroenterology & Hepatology

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

Sina Bartfeld et al.

GASTROENTEROLOGY (2015)

Review Pharmacology & Pharmacy

Inkjet printing for pharmaceutics - A review of research and manufacturing

Ronan Daly et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

Article Biotechnology & Applied Microbiology

A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype

Luke Cassereau et al.

JOURNAL OF BIOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost et al.

NATURE (2015)

Article Biotechnology & Applied Microbiology

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Ryuji Morizane et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids

Mami Matano et al.

NATURE MEDICINE (2015)

Review Multidisciplinary Sciences

Neoantigens in cancer immunotherapy

Ton N. Schumacher et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Naiyer A. Rizvi et al.

SCIENCE (2015)

Article Biotechnology & Applied Microbiology

Proteome array identification of bioactive soluble proteins/peptides in Matrigel: relevance to stem cell responses

Neil C. Talbot et al.

CYTOTECHNOLOGY (2015)

Review Nanoscience & Nanotechnology

Rheology of peptide- and protein-based physical hydrogels: Are everyday measurements just scratching the surface?

Sameer Sathaye et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2015)

Article Engineering, Biomedical

Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro

Aleksander Skardal et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

Review Pharmacology & Pharmacy

Matrigel: From discovery and ECM mimicry to assays and models for cancer research

Gabriel Benton et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Article Engineering, Biomedical

A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

Simone Bersini et al.

BIOMATERIALS (2014)

Article Biochemistry & Molecular Biology

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

Dong Gao et al.

Editorial Material Biochemistry & Molecular Biology

Genes, the environment and personalized medicine

Chris Carlsten et al.

EMBO REPORTS (2014)

Review Cardiac & Cardiovascular Systems

Bioprinting of artificial blood vessels: current approaches towards a demanding goal

Eva Hoch et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2014)

Article Cell Biology

Rotary bioreactor culture can discern specific behavior phenotypes in Trk-null and Trk-expressing neuroblastoma cell lines

Robert A. Redden et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2014)

Article Nanoscience & Nanotechnology

Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels

Shreyas S. Rao et al.

ACS APPLIED MATERIALS & INTERFACES (2013)

Review Biotechnology & Applied Microbiology

Biofabrication: an overview of the approaches used for printing of living cells

Cameron J. Ferris et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)

Article Biochemistry & Molecular Biology

Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

Kevin J. Cheung et al.

Editorial Material Oncology

Precision Oncology: An Overview

Levi A. Garraway et al.

JOURNAL OF CLINICAL ONCOLOGY (2013)

Article Multidisciplinary Sciences

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster et al.

NATURE (2013)

Review Biochemistry & Molecular Biology

Microenvironmental regulation of tumor progression and metastasis

Daniela F. Quail et al.

NATURE MEDICINE (2013)

Article Biochemical Research Methods

Three-dimensional cell culturing by magnetic levitation

William L. Haisler et al.

NATURE PROTOCOLS (2013)

Article Multidisciplinary Sciences

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

Kim-Vy Nguyen-Ngoc et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Multidisciplinary Sciences

Designing Cell-Compatible Hydrogels for Biomedical Applications

Dror Seliktar

SCIENCE (2012)

Review Biochemistry & Molecular Biology

Biopolymer-Based Hydrogels As Scaffolds for Tissue Engineering Applications: A Review

S. Van Vlierberghe et al.

BIOMACROMOLECULES (2011)

Article Biochemical Research Methods

Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting

Huiping Liu et al.

JOURNAL OF VIROLOGICAL METHODS (2011)

Article Pharmacology & Pharmacy

Effect of crosslinker concentration on characteristics of superporous hydrogel

H. V. Chavda et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2011)

Article Reproductive Biology

Development and Characterization of a Three-Dimensional Organotypic Human Vaginal Epithelial Cell Model

Brooke E. Hjelm et al.

BIOLOGY OF REPRODUCTION (2010)

Review Biochemistry & Molecular Biology

The tumor microenvironment and its role in promoting tumor growth

T. L. Whiteside

ONCOGENE (2008)

Review Immunology

Foreign body reaction to biomaterials

James M. Anderson et al.

SEMINARS IN IMMUNOLOGY (2008)

Review Biochemistry & Molecular Biology

Tumor metastasis: mechanistic insights and clinical challenges

Patricia S. Steeg

NATURE MEDICINE (2006)

Article Engineering, Electrical & Electronic

Acoustic picoliter droplets for emerging applications in semiconductor industry and biotechnology

Utkan Demirci

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2006)

Review Oncology

Matrigel: Basement membrane matrix with biological activity

HK Kleinman et al.

SEMINARS IN CANCER BIOLOGY (2005)

Article Biochemical Research Methods

A simple technique for reducing edge effect in cell-based assays

BK Lundholt et al.

JOURNAL OF BIOMOLECULAR SCREENING (2003)

Article Engineering, Biomedical

Photopolymerizable hydrogels for tissue engineering applications

KT Nguyen et al.

BIOMATERIALS (2002)

Review Chemistry, Multidisciplinary

Hydrogels for tissue engineering

KY Lee et al.

CHEMICAL REVIEWS (2001)