4.6 Article

Pharmaceutical polymers and P-glycoprotein: Current trends and possible outcomes in drug delivery

Related references

Note: Only part of the references are listed.
Article Chemistry, Physical

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

Nehal E. Elsadek et al.

Summary: Electrospinning is a customizable drug delivery technique that fabricates drug-loaded nanofibers using various polymers. These nanofibers have applications in cancer therapy, microbial infections, and regenerative medicine. They offer controlled drug release, high loading capability, and cost-effectiveness, making them promising for improving chemotherapy efficiency, antimicrobial drug delivery, wound healing, and tissue regeneration.

MATERIALS (2022)

Article Biochemistry & Molecular Biology

Biofabrication of Sodium Alginate Hydrogel Scaffolds for Heart Valve Tissue Engineering

Yannick Rioux et al.

Summary: This article presents a novel technique for rapid fabrication of native-like tricuspid aortic valve scaffolds using an alginate-based hydrogel. The technique involves injecting a sodium alginate hydrogel formulation into a mold produced using a custom-made sugar glass 3D printer, and dissolving the mold using a custom-made dissolving module. The results of CT scans and tests in a cardiac bioreactor demonstrate the functional repeatability of this new biofabrication method, suggesting its potential for rapid fabrication of cell-seeded sodium alginate scaffolds for heart valve tissue engineering.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Review Biochemistry & Molecular Biology

Recent Advances of Chitosan Formulations in Biomedical Applications

Mohammed A. S. Abourehab et al.

Summary: Chitosan, a naturally abundant cationic polymer, offers attractive characteristics such as renewability, hydrophilicity, biodegradability, biocompatibility, and antimicrobial activity. It has a wide range of applications in drug delivery, protective coatings, food packaging, and wastewater treatment. The structure of chitosan allows for various reactions and electrochemical interactions, improving its physicochemical properties. This review article discusses the extensive research on chitosan-based composites for drug, gene, protein, and vaccine delivery applications, as well as its applications in tissue engineering and wound healing. The challenges and future perspectives for chitosan in biomedical applications are also addressed.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Chemistry, Medicinal

Development of Biocomposite Alginate-Cuttlebone-Gelatin 3D Printing Inks Designed for Scaffolds with Bone Regeneration Potential

Filis Curti et al.

Summary: Fabricating three-dimensional scaffolds using natural biomaterials has great potential in bone tissue reconstruction and regeneration. This study developed paste-like 3D printing inks based on marine materials, including sodium alginate, cuttlebone, and fish gelatin. The results showed that these inks can produce macroporous scaffolds with microporous biocomposite filaments, demonstrating promising mechanical properties and cell adhesion.

MARINE DRUGS (2022)

Review Polymer Science

Gellan Gum in Wound Dressing Scaffolds

Zizo Feketshane et al.

Summary: Factors such as bacterial infections, underlying conditions, malnutrition, obesity, aging, and smoking contribute to delayed wound healing. Gellan gum, a biopolymer with excellent properties, can be utilized for the development of wound dressings that promote accelerated wound healing.

POLYMERS (2022)

Review Polymer Science

Poloxamer-Based Scaffolds for Tissue Engineering Applications: A Review

Naiyu Cui et al.

Summary: Poloxamer, as a triblock copolymer with amphiphilicity and reversible thermal responsiveness, has wide application prospects in biomedicine. It plays a crucial role as injectable scaffolds in tissue engineering and 3D printing, creating an appropriate microenvironment for cell growth and vascular network formation.
Review Biochemistry & Molecular Biology

Thiolated Chitosans: A Multi-talented Class of Polymers for Various Applications

Christoph Federer et al.

Summary: Thiolation of chitosan allows for customization of various properties to meet specific needs in a wide range of application areas, with advantageous characteristics such as adhesion, adjustable cross-linking and swelling behavior, controllable drug release, cellular uptake enhancement, complexation of metal ions, and antioxidative properties, while remaining biodegradable without increased toxicity.

BIOMACROMOLECULES (2021)

Article Medicine, Research & Experimental

Poloxamer 188-Coated Ammonium Methacrylate Copolymer Nanocarriers Enhance Loperamide Permeability across Pgp-Expressing Epithelia

Johanna Catalan-Figueroa et al.

Summary: The study shows that formulating loperamide into nanocarriers enhances its uptake and transport permeability. P188, as a potential negative Pgp modulator, can increase loperamide uptake when used in preincubation conditions, which could be significant for overcoming Pgp limitations.

MOLECULAR PHARMACEUTICS (2021)

Article Chemistry, Applied

Computational and experimental approaches for chitosan-based nano PECs design: Insights on a deeper comprehension of nanostructure formation

Fernanda Isadora Boni et al.

Summary: Nanostructured polyelectrolyte complexes based on biopolymers are designed through computational studies to target drugs more effectively to specific action and absorption sites. The optimal pH range for preparing nano PECs was determined experimentally and computationally, resulting in successful preparation of spherical nano-sized particles with positive surface charge. The study also rationalized the addition order of biopolymers and drug, maximizing their interactions and drug entrapment efficiency.

CARBOHYDRATE POLYMERS (2021)

Review Chemistry, Medicinal

Chitosan-Based Scaffold for Mineralized Tissues Regeneration

Teerawat Sukpaita et al.

Summary: This review provides an overview of chitosan-based biomaterials for bone tissue engineering and their applications in treating bone defects. The focus is on the characteristics of chitosan, scaffold fabrication processes, advantages and disadvantages, and future directions in the field.

MARINE DRUGS (2021)

Review Education, Scientific Disciplines

Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs

Mohamed Salah Attia et al.

Summary: Solid dispersion is an old and widely used technique to improve the solubility of slowly dissolving drugs, with various methods and carriers available. Novel methods such as KinetiSol, electrospinning, and hot-melt extrusion are being applied to enhance the scalability of the approach.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2021)

Review Pharmacology & Pharmacy

Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability

Thi-Thao-Linh Nguyen et al.

Summary: P-glycoprotein (P-gp) plays a crucial role in the active transport of substrates out of cells, leading to poor intestinal permeation. Utilizing P-gp inhibitors and pharmaceutically inert excipients can help enhance the oral absorption and bioavailability of P-gp substrates. Different formulations with inherent P-gp inhibitory activity have been developed, offering a promising strategy to bypass P-gp and improve drug delivery.

PHARMACEUTICS (2021)

Article Chemistry, Multidisciplinary

Preparation and characterization of sodium alginate-PVA polymeric scaffolds by electrospinning method for skin tissue engineering applications

Sorour Jadbabaei et al.

Summary: By optimizing the ratio of SA and PVA, this study successfully improved the spinnability of SA and determined the best electrospinning parameters. The fabricated nanofiber scaffolds exhibited good physical, chemical, mechanical, and biological properties, making them suitable candidates for skin tissue engineering.

RSC ADVANCES (2021)

Review Chemistry, Multidisciplinary

Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery

Liwang Shi et al.

Summary: This review discusses the impact of PEG coverage density and thickness on the biophysical and chemical properties of nanoparticles, as well as the related techniques used to detect these coverages.

NANOSCALE (2021)

Review Pharmacology & Pharmacy

Challenges and opportunities in the delivery of cancer therapeutics: update on recent progress

Mathilde Lorscheider et al.

Summary: Global cancer prevalence has been increasing, leading to the importance of drug administration route choice and innovative drug-delivery systems. The diverse physicochemical properties of therapeutic cancer drugs present challenges, but innovative DDS has made progress to address them.

THERAPEUTIC DELIVERY (2021)

Review Cell Biology

Nanoparticles and cancer therapy: Perspectives for application of nanoparticles in the treatment of cancers

Ali Aghebati-Maleki et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Review Oncology

Perplexing Role of P-Glycoprotein in Tumor Microenvironment

Kianna Robinson et al.

FRONTIERS IN ONCOLOGY (2020)

Article Pharmacology & Pharmacy

Molecular dynamics study on the encapsulation and release of anti-cancer drug doxorubicin by chitosan

Jiachen Li et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Chemistry, Medicinal

Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening

Tanya Smit et al.

ACS MEDICINAL CHEMISTRY LETTERS (2020)

Article Biochemistry & Molecular Biology

An injectable chitosan-based hydrogel scaffold containing gold nanoparticles for tissue engineering applications

Parinaz Nezhad-Mokhtari et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Thiolated sodium alginate conjugates for mucoadhesive and controlled release behavior of metformin microspheres

Siddra Khalid et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

High-resolution 3D printing of xanthan gum/nanocellulose bio-inks

Hossein Baniasadi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Pharmacology & Pharmacy

Optimization and in-vitro/in-vivo evaluation of doxorubicin-loaded chitosan-alginate nanoparticles using a melanoma mouse model

Krassimira Yoncheva et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Pharmacology & Pharmacy

Solubility and bioavailability enhancement study of lopinavir solid dispersion matrixed with a polymeric surfactant - Soluplus

Peng Zi et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

Review Pharmacology & Pharmacy

Poloxamer Hydrogels for Biomedical Applications

Eleonora Russo et al.

PHARMACEUTICS (2019)

Review Pharmacology & Pharmacy

Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy

Eun-Kyung Lim et al.

CURRENT DRUG TARGETS (2018)

Article Nanoscience & Nanotechnology

Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine

Wei Xiong et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

Article Chemistry, Multidisciplinary

Tacrolimus Loaded PEG-Cholecalciferol Based Micelles for Treatment of Ocular Inflammation

Shallu Kutlehria et al.

PHARMACEUTICAL RESEARCH (2018)

Review Multidisciplinary Sciences

Progress and challenges towards targeted delivery of cancer therapeutics

Daniel Rosenblum et al.

NATURE COMMUNICATIONS (2018)

Article Pharmacology & Pharmacy

Emerging advances in P-glycoprotein inhibitory nanomaterials for drug delivery

Longfa Kou et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

Article Medicine, Research & Experimental

Inhibitory Effects of Commonly Used Excipients on P-Glycoprotein in Vitro

Rohan Gurjar et al.

MOLECULAR PHARMACEUTICS (2018)

Review Engineering, Biomedical

Formulation of Poloxamers for Drug Delivery

Andrew M. Bodratti et al.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2018)

Article Biotechnology & Applied Microbiology

Role of P-Glycoprotein Inhibitors in the Bioavailability Enhancement of Solid Dispersion of Darunavir

Saleha Rehman et al.

BIOMED RESEARCH INTERNATIONAL (2017)

Article Pharmacology & Pharmacy

Development of an Ointment Formulation Using Hot-Melt Extrusion Technology

Ajinkya M. Bhagurkar et al.

AAPS PHARMSCITECH (2016)

Article Biophysics

Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment

Rahul Pratap Singh et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2016)

Article Pharmacology & Pharmacy

Polymeric Drug-Delivery Systems: Role in P-gp Efflux System Inhibition

Preeti Gupta et al.

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2015)

Article Materials Science, Biomaterials

Co-delivery of docetaxel and Poloxamer 235 by PLGA-TPGS nanoparticles for breast cancer treatment

Xiaolong Tang et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2015)

Article Medicine, Research & Experimental

Oral Absorption Enhancement of Probucol by PEGylated G5 PAMAM Dendrimer Modified Nanoliposomes

Qian Ma et al.

MOLECULAR PHARMACEUTICS (2015)

Review Pharmacology & Pharmacy

Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy

Renata Silva et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Review Polymer Science

Natural and Synthetic Polymers as Drug Carriers for Delivery of Therapeutic Proteins

Muhammad Sajid Hamid Akash et al.

POLYMER REVIEWS (2015)

Review Biotechnology & Applied Microbiology

Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy

Famida G. Hoosain et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Review Pharmacology & Pharmacy

Guar gum as platform for the oral controlled release of therapeutics

Tejraj M. Aminabhavi et al.

EXPERT OPINION ON DRUG DELIVERY (2014)

Review Chemistry, Medicinal

Marine Natural Products with P-Glycoprotein Inhibitor Properties

Dioxelis Lopez et al.

MARINE DRUGS (2014)

Review Polymer Science

Dendrimer as nanocarrier for drug delivery

Prashant Kesharwani et al.

PROGRESS IN POLYMER SCIENCE (2014)

Review Pharmacology & Pharmacy

Pharmaceutical nanotechnology for oral delivery of anticancer drugs

Lin Mei et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

Review Oncology

Acidic extracellular microenvironment and cancer

Yasumasa Kato et al.

CANCER CELL INTERNATIONAL (2013)

Article Pharmacology & Pharmacy

Poly(amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin

S. Sadekar et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Review Pharmacology & Pharmacy

P-glycoprotein Inhibition for Optimal Drug Delivery

Md. Lutful Amin

DRUG TARGET INSIGHTS (2013)

Article Chemistry, Applied

In vitro properties of gellan gum sponge as the dental filling to maintain alveolar space

Shwu Jen Chang et al.

CARBOHYDRATE POLYMERS (2012)

Article Pharmacology & Pharmacy

Oral administration of paclitaxel with pegylated poly(anhydride) nanoparticles: Permeability and pharmacokinetic study

Virginia Zabaleta et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)

Article Pharmacology & Pharmacy

Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects

Yu Mi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)

Review Polymer Science

Alginate: Properties and biomedical applications

Kuen Yong Lee et al.

PROGRESS IN POLYMER SCIENCE (2012)

Review Pharmacology & Pharmacy

Formulation strategies for drug delivery of tacrolimus: An overview

Pranav Patel et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2012)

Article Cardiac & Cardiovascular Systems

Dabigatran Etexilate A New Oral Thrombin Inhibitor

Graeme J. Hankey et al.

CIRCULATION (2011)

Review Chemistry, Medicinal

The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review

Naseem Akhtar et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2011)

Article Chemistry, Multidisciplinary

G3.5 PAMAM dendrimers enhance transepithelial transport of SN38 while minimizing gastrointestinal toxicity

Deborah S. Goldberg et al.

JOURNAL OF CONTROLLED RELEASE (2011)

Article Chemistry, Medicinal

Enhanced Oral Absorption of Paclitaxel in N-Deoxycholic Acid-N, O-Hydroxyethyl Chitosan Micellar System

Hong Li et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Chemistry, Applied

Electrospinning of chitosan nanofibers: Processing optimization

Homa Homayoni et al.

CARBOHYDRATE POLYMERS (2009)

Review Pharmacology & Pharmacy

Dendrimers: Emerging polymers for drug-delivery systems

Basavaraj K. Nanjwade et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

Article Chemistry, Physical

Molecular structure, lipophilicity, solubility, absorption, and polar surface area of novel anticoagulant agents

Milan Remko

JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM (2009)

Article Pharmacology & Pharmacy

A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery:: Rheological, mucoadhesive and in vitro release properties

Laura Mayol et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2008)

Article Pharmacology & Pharmacy

Effect of pluronic F68 block copolymer on P-glycoprotein transport and CYP3A4 metabolism

Jiangeng Huang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)

Review Chemistry, Multidisciplinary

Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers

Elena V. Batrakova et al.

JOURNAL OF CONTROLLED RELEASE (2008)

Review Pharmacology & Pharmacy

Thiolated chitosans: useful excipients for oral drug delivery

Martin Werle et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2008)

Review Chemistry, Multidisciplinary

Natural and synthetic polymers as inhibitors of drug efflux pumps

Martin Werle

PHARMACEUTICAL RESEARCH (2008)

Review Pharmacology & Pharmacy

The effects of pharmaceutical excipients on drug disposition

Talia R. Buggins et al.

ADVANCED DRUG DELIVERY REVIEWS (2007)

Article Medicine, Research & Experimental

Surfactant-polymer nanoparticles overcome P-glycoprotein-mediated drug efflux

Mahesh D. Chavanpatil et al.

MOLECULAR PHARMACEUTICS (2007)

Article Chemistry, Medicinal

Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum

Gemma O'Donnell et al.

PHYTOTHERAPY RESEARCH (2007)

Article Pharmacology & Pharmacy

In vitro evaluation of dendrimer prodrugs for oral drug delivery

Mohammad Najlah et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Pharmacology & Pharmacy

Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan

Florian Foegert et al.

JOURNAL OF DRUG TARGETING (2007)

Review Pharmacology & Pharmacy

Thermo- and pH-responsive polymers in drug delivery

Dirk Schmaljohann

ADVANCED DRUG DELIVERY REVIEWS (2006)

Article Microbiology

Role of P glycoprotein in absorption of novel antimalarial drugs

Andrew Crowe et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

Article Engineering, Biomedical

In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan

Florian Foeger et al.

BIOMATERIALS (2006)

Article Chemistry, Multidisciplinary

Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine

M Werle et al.

JOURNAL OF CONTROLLED RELEASE (2006)

Article Medicine, Research & Experimental

Scientific perspectives on drug transporters and their role in drug interactions

Lei Zhang et al.

MOLECULAR PHARMACEUTICS (2006)

Review Pharmacology & Pharmacy

Dendrimers in gene delivery

C Dufès et al.

ADVANCED DRUG DELIVERY REVIEWS (2005)

Review Pharmacology & Pharmacy

PEGylation, successful approach to drug delivery

FM Veronese et al.

DRUG DISCOVERY TODAY (2005)

Article Pharmacology & Pharmacy

Enhanced oral paclitaxel absorption with vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo

MVS Varma et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2005)

Review Medicine, Research & Experimental

PAMAM dendrimer based macromolecules as improved contrast agents

Vincent J. Venditto et al.

MOLECULAR PHARMACEUTICS (2005)

Article Pharmacology & Pharmacy

Surface morphology control of polylactide microspheres enclosing irinotecan hydrochloride

H Yoshizawa et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2005)

Review Pharmacology & Pharmacy

Dendrimers and dendritic polymers in drug delivery

ER Gillies et al.

DRUG DISCOVERY TODAY (2005)

Article Chemistry, Multidisciplinary

The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability

A D'Emanuele et al.

JOURNAL OF CONTROLLED RELEASE (2004)

Review Pharmacology & Pharmacy

Importance of P-glycoprotein at blood-tissue barriers

MF Fromm

TRENDS IN PHARMACOLOGICAL SCIENCES (2004)

Article Biochemistry & Molecular Biology

Pyronaridine, a novel modulator of P-glycoprotein-mediated multidrug resistance in tumor cells in vitro and in vivo

J Qi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Review Biochemistry & Molecular Biology

Antibacterial resistance worldwide: causes, challenges and responses

SB Levy et al.

NATURE MEDICINE (2004)

Article Engineering, Biomedical

Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth

NO Dhoot et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2004)

Review Biochemistry & Molecular Biology

Mechanisms of resistance to antibiotics

GD Wright

CURRENT OPINION IN CHEMICAL BIOLOGY (2003)

Article Pharmacology & Pharmacy

P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement

MVS Varma et al.

PHARMACOLOGICAL RESEARCH (2003)

Article Chemistry, Multidisciplinary

Engineering of dendrimer surfaces to enhance transepithelial transport and reduce cytotoxicity

R Jevprasesphant et al.

PHARMACEUTICAL RESEARCH (2003)

Article Chemistry, Medicinal

The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins

K Bogman et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2003)

Article Microbiology

Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages

C Seral et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)

Review Pharmacology & Pharmacy

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

AH Schinkel et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)

Article Infectious Diseases

A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus

S Gibbons et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2003)

Review Pharmacology & Pharmacy

Role of P-glycoprotein in pharmacokinetics - Clinical implications

JH Lin et al.

CLINICAL PHARMACOKINETICS (2003)

Article Chemistry, Medicinal

Automated analysis of polyethylene glycol-induced inhibition of P-glycoprotein activity in vitro

ED Hugger et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2003)

Article Pharmacology & Pharmacy

Interaction of cytochrome P450 3A inhibitors with P-glycoprotein

K Yasuda et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)

Review Chemistry, Multidisciplinary

Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery

AV Kabanov et al.

JOURNAL OF CONTROLLED RELEASE (2002)

Article Biotechnology & Applied Microbiology

Mechanisms of bacterial biocide and antibiotic resistance

K Poole

JOURNAL OF APPLIED MICROBIOLOGY (2002)

Article Biochemistry & Molecular Biology

Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT

YT Pham et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2000)

Article Medical Laboratory Technology

Role of P-glycoprotein in drug disposition

Y Tanigawara

THERAPEUTIC DRUG MONITORING (2000)