Undernutrition Scored Using the CONUT Score with Hypoglycemic Status in ICU-Admitted Elderly Patients with Sepsis Shows Increased ICU Mortality

This study aimed to clarify whether the influence of undernutrition status and the degree of glycemic disorders affected the prognosis of patients with sepsis. A total of 307 adult patients with sepsis were retrospectively enrolled and analyzed. Characteristics, including nutrition status, calculated according to the Controlling Nutritional Status (CONUT) score of survivors and non-survivors, were examined. The independent prognostic factors of these patients with sepsis were extracted using multivariable logistic regression analysis. The CONUT scores in three glycemic categories were compared. Most patients with sepsis (94.8%) in the study had an undernutrition status according to their CONUT scores. High CONUT scores (odds ratio, 1.214; p = 0.002), indicating a poor nutritional status, were associated with high mortality. The CONUT scores in the hypoglycemic group were significantly higher than those in other groups with an undernutrition status (vs. hyperglycemic, p < 0.001; vs. intermediate glycemic, p = 0.006). The undernutrition statuses of patients with sepsis in the study scored using the CONUT were independent predictors of prognostic factors.

Automated summary

This study aimed to investigate whether undernutrition status and the degree of glycemic disorders had an impact on the prognosis of sepsis patients. A total of 307 adult patients with sepsis were included in the retrospective analysis. The study found that most sepsis patients had an undernutrition status according to their CONUT scores. High CONUT scores were associated with higher mortality rates, and the CONUT scores in the hypoglycemic group were significantly higher than those in other groups with undernutrition status. The undernutrition statuses of sepsis patients, as evaluated by the CONUT scores, were independent predictors of prognosis factors.