4.6 Editorial Material

Editorial for the Special Issue: Current Technique for Antibiotic Susceptibility Test: Advantages and Limitations; Need for Next-Generation Test

Related references

Note: Only part of the references are listed.
Article Infectious Diseases

Cumulative Antibiogram: A Rapid Method to Hinder Transmission of Resistant Bacteria to Oral Cavity of Newborn Babies

Madalina Adriana Malita et al.

Summary: This study assessed the antibiotic resistance profile in childbearing women and newborns, and found a prevalence of 11.32% for antibiotic resistance. The prevalence of specific antibiotic-resistant strains, such as ESBL-E, CRE, VRE, MRSA, and VR-GBS, was 8.34%. Resistant bacteria were also detected in the oral cavity of newborns. Overall, the cumulative antibiogram is useful for empirical treatment in various emergency situations, including the transmission of resistant bacteria to the oral cavity of newborns.

ANTIBIOTICS-BASEL (2023)

Article Infectious Diseases

Relationship between Phenotypic and Genotypic Resistance of Subgingival Biofilm Samples in Patients with Periodontitis

Moritz Sparbrod et al.

Summary: This study analyzed the relationship between phenotypic and genotypic resistance against several antibiotics in subgingival biofilm samples from periodontitis patients. The genetic profile of 8 patients completely matched with phenotypic resistance. The absence of nimI gene and the presence of erm gene correlated with phenotypic resistance to metronidazole and clindamycin, respectively.

ANTIBIOTICS-BASEL (2023)

Article Infectious Diseases

Antimicrobial Susceptibility Profile of Rare Anaerobic Bacteria

Lena Josephine Wolf et al.

Summary: Anaerobes play a crucial role in clinically relevant infections and their resistance is becoming more widespread. In this study, 120 rare anaerobic isolates from 16 genera were tested for antimicrobial resistance using two different methods. Results showed low resistance to certain antibiotics, while moderate to high rates of resistance were observed for others, depending on the testing methodology. The findings highlight the importance of routine susceptibility testing and further investigations are needed to improve testing for fastidious anaerobes.

ANTIBIOTICS-BASEL (2023)

Article Infectious Diseases

Trends in Antibiotic Resistance of Nosocomial and Community-Acquired Infections in Italy

Paola Cerini et al.

Summary: The World Health Organization has identified three categories of pathogens based on the need for new antibiotics: critical, high, and medium priority. The prevalence of antibiotic resistant bacteria, such as CPO, MRSA, and VRE, has increased from 2019 to 2022 in both nosocomial and community patients. This highlights the importance of implementing preventive and control measures to reduce the spread of multidrug-resistant pathogens.

ANTIBIOTICS-BASEL (2023)

Article Infectious Diseases

Anti-Infective Treatment and Resistance Is Rarely Problematic with Eye Infections

Regis P. Kowalski et al.

Summary: This article discusses the treatment and diagnosis of eye infections, the development of anti-infective resistance, and alternative therapies. It emphasizes the importance of laboratory diagnosis and prompt and potent anti-infective therapy in reducing the severity of eye infections. It also highlights the need for monitoring susceptibility and exploring new treatment methods.

ANTIBIOTICS-BASEL (2022)

Article Infectious Diseases

Conventional and Real-Time PCR Targeting blaOXA Genes as Reliable Methods for a Rapid Detection of Carbapenem-Resistant Acinetobacter baumannii Clinical Strains

Dagmara Depka et al.

Summary: This study aimed to evaluate different detection methods for carbapenemases and found that both conventional PCR and real-time PCR showed high sensitivity in detecting carbapenem-resistant strains, making them valuable tools for accurate diagnosis.

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Review Infectious Diseases

Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods

Ina Gajic et al.

Summary: Antimicrobial resistance poses a significant threat to global public health. Accurate and rapid detection of antibiotic resistance and appropriate treatment methods are crucial for controlling its emergence. However, traditional testing methods are time-consuming and costly, highlighting the need for innovative approaches.

ANTIBIOTICS-BASEL (2022)

Article Infectious Diseases

Bacterial Infection Diagnosis and Antibiotic Prescription in 3 h as an Answer to Antibiotic Resistance: The Case of Urinary Tract Infections

Eleonora Nicolai et al.

Summary: The current methods for the diagnosis of UTIs and antimicrobial susceptibility testing take 2-3 days and lack rapid point-of-care AST, leading to antibiotic misuse and multi-drug-resistant organisms. A novel rapid phenotypic AST device can determine antibiotic susceptibility/resistance within 3 hours, which could help in early recognition of effective treatment options for individual patients.

ANTIBIOTICS-BASEL (2021)

Article Infectious Diseases

A Combined Phenotypic-Genotypic Predictive Algorithm for In Vitro Detection of Bicarbonate: β-Lactam Sensitization among Methicillin-Resistant Staphylococcus aureus (MRSA)

Selvi C. Ersoy et al.

Summary: Antimicrobial susceptibility testing (AST) is used to predict antibiotic resistance in bacterial pathogens for treatment. A novel phenotype, NaHCO3-responsiveness, was identified in clinical MRSA strains, showing susceptibility to beta-lactams in the presence of NaHCO3. Combining AMC disk susceptibility testing with mecA and spa genotyping can predict MRSA strains' responsiveness to NaHCO3 with high sensitivity and specificity.

ANTIBIOTICS-BASEL (2021)