Journal
METABOLITES
Volume 13, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/metabo13030341
Keywords
gene expression; phenylpropanoids; terpenoids; alkaloids; biosynthesis
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Despite a rich history and economic importance, the potential of medicinal plants has not been fully explored under different abiotic stress conditions. The penetration of UV-B radiation and contamination of heavy metals have a significant impact on the defense-related and pharmaceutically important secondary metabolites of medicinal plants, which can affect both the quality and quantity of these metabolites. Understanding the effects of UV-B and heavy metal contamination on the biosynthesis and accumulation of secondary metabolites is important for the comprehensive study of medicinal plants.
Despite a rich history and economic importance, the potential of medicinal plants has not been fully explored under different abiotic stress conditions. Penetration of UV-B radiation and contamination of heavy metals are two important environmental stress for plants with remarkable influence on the defense-related and pharmaceutically important secondary metabolites of medicinal plants. UV-B and heavy metal contamination may become a critical issue that either positively or negatively affects the quality and quantity of secondary metabolites. Such effects may result from changes in the expression level of genes that encode the corresponding enzymes or the inactivation and/or stimulation of specific enzymes involved in the different biosynthetic pathways of the secondary metabolites. Therefore, a comprehensive study of the impact of UV-B and heavy metals individually and in combination on the biosynthesis and accumulation of secondary metabolites in medicinal plants is discussed in the present review.
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