4.6 Editorial Material

Editorial for Special Issue Unleashing the Hidden Potential of Anaerobic Fungi

Related references

Note: Only part of the references are listed.
Article Microbiology

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Summary: This study reveals the selective enrichment of certain genera in media with rumen fluid and depleted rumen fluid from rumen and non-rumen samples,respectively. Additionally, five new clades were defined from fecal samples of llama, guanaco, yak, and elephant. Therefore, the non-rumen fluid medium is recommended for isolating anaerobic fungi from non-rumen environments.

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Summary: Lignocellulose is a promising feedstock for biofuel production, but pretreatments are needed to overcome its natural recalcitrance. Anaerobic fungi have potential for biofuel production due to their effective ability to hydrolyse lignocellulose and convert it to H-2 and ethanol, as well as produce volatile fatty acid precursors for further conversion.

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Summary: The study investigates the isolation and identification of five strains of anaerobic fungi, revealing their main metabolic products with a preference for hydrogen, acetate, and formate. Differences in growth and metabolic products on different carbon sources, as well as reactions to elevated sugar concentrations, were discussed.

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Anaerobic Fungal Mevalonate Pathway Genomic Biases Lead to Heterologous Toxicity Underpredicted by Codon Adaptation Indices

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Summary: Anaerobic fungi have rich biosynthetic potential, but their biosynthetic pathways have limited success in model hosts like E. coli. This is due to the extreme AT bias in the genome of anaerobic fungi like P. indianae, which causes growth defects in E. coli. Codon optimization rescues growth and enables gene evaluation in otherwise difficult to express genes.

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