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ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2013)
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
Melba C. Jaramillo et al.
GENES & DEVELOPMENT (2013)
Understanding the Molecular Aspects of Tetrahydrocannabinol and Cannabidiol as Antioxidants
Rosivaldo S. Borges et al.
MOLECULES (2013)
Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
M. Mecha et al.
NEUROBIOLOGY OF DISEASE (2013)
Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells
Ana Juknat et al.
PLOS ONE (2013)
Endocannabinoid system and mood disorders: Priming a target for new therapies
Vincenzo Micale et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses
Sergiy Sylantyev et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Why should Cannabis be Considered Doping in Sports?
Mateus M. Bergamaschi et al.
Frontiers in Psychiatry (2013)
Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington's Disease: Role of CB1 and CB2 Receptors
Sara Valdeolivas et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells
Ana Juknat et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis
Tatiana Barichello et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Endocannabinoid Signaling and Synaptic Function
Pablo E. Castillo et al.
NEURON (2012)
Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
M. R. Pazos et al.
NEUROPHARMACOLOGY (2012)
CANNABINOID TYPE 1 RECEPTORS AND TRANSIENT RECEPTOR POTENTIAL VANILLOID TYPE 1 CHANNELS IN FEAR AND ANXIETY-TWO SIDES OF ONE COIN?
F. A. Moreira et al.
NEUROSCIENCE (2012)
CONTRIBUTIONS OF ENDOCANNABINOID SIGNALING TO PSYCHIATRIC DISORDERS IN HUMANS: GENETIC AND BIOCHEMICAL EVIDENCE
C. J. Hillard et al.
NEUROSCIENCE (2012)
Phytocannabinoids as novel therapeutic agents in CNS disorders
Andrew J. Hill et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
Elen V. Fagherazzi et al.
PSYCHOPHARMACOLOGY (2012)
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
F. M. Leweke et al.
TRANSLATIONAL PSYCHIATRY (2012)
Cannabidiol in Humans-The Quest for Therapeutic Targets
Simon Zhornitsky et al.
PHARMACEUTICALS (2012)
Prospects for cannabinoid therapies in basal ganglia disorders
Javier Fernandez-Ruiz et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes
Luciano De Petrocellis et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Cannabinoids: Occurrence and Medicinal Chemistry
G. Appendino et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
George W. Booz
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Neuroprotective Effects of Phytocannabinoid-Based Medicines in Experimental Models of Huntington's Disease
Onintza Sagredo et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania
Samira S. Valvassori et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2011)
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
Jose Alexandre S. Crippa et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2011)
Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy
Ashutosh Shrivastava et al.
MOLECULAR CANCER THERAPEUTICS (2011)
Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease
Ana Maria Martin-Moreno et al.
MOLECULAR PHARMACOLOGY (2011)
Cannabidiol Reduces Ab- Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
Giuseppe Esposito et al.
PLOS ONE (2011)
The dopamine and cannabinoid interaction in the modulation of emotions and cognition: assessing the role of cannabinoid CB1 receptor in neurons expressing dopamine D1 receptors
Ana Luisa Terzian et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2011)
Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice
Hye-Youn Cho et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Thioredoxin and thioredoxin reductase: Current research with special reference to human disease
Arne Holmgren et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture
Omar J. Cassol- et al.
BRAIN RESEARCH (2010)
Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
I. Magen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
CB2: a cannabinoid receptor with an identity crisis
Brady K. Atwood et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Impact of cannabidiol on the acute and psychotomimetic effects of smoked cannabis: naturalistic study
Celia J. A. Morgan et al.
BRITISH JOURNAL OF PSYCHIATRY (2010)
Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription
Marcus J. Calkins et al.
EXPERIMENTAL NEUROLOGY (2010)
The endocannabinoid system as a target for the treatment of neuronal damage
Javier Fernandez-Ruiz et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Eicosanoids and the endogenous control of acute inflammatory resolution
Derek W. Gilroy
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells
Ewa Kozela et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
William R. Marrs et al.
NATURE NEUROSCIENCE (2010)
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB2 and adenosine receptors
A. Castillo et al.
NEUROBIOLOGY OF DISEASE (2010)
Performance of schizophrenic patients in the Stroop Color Word Test and electrodermal responsiveness after acute administration of cannabidiol (CBD)
Jaime E. C. Hallak et al.
REVISTA BRASILEIRA DE PSIQUIATRIA (2010)
CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages
Ki Hoon Han et al.
CARDIOVASCULAR RESEARCH (2009)
Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation
Iddo Magen et al.
JOURNAL OF HEPATOLOGY (2009)
Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death
Hao Pan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Cannabidiol for the treatment of psychosis in Parkinson's disease
A. W. Zuardi et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2009)
NEUROPROTECTIVE EFFECTS OF R,R-TETRAHYDROCHRYSENE AGAINST GLUTAMATE-INDUCED CELL DEATH THROUGH ANTI-EXCITOTOXIC AND ANTIOXIDANT ACTIONS INVOLVING ESTROGEN RECEPTOR-DEPENDENT AND -INDEPENDENT PATHWAYS
Y. Xia et al.
NEUROSCIENCE (2009)
Endocannabinoid-Mediated Control of Synaptic Transmission
Masanobu Kano et al.
PHYSIOLOGICAL REVIEWS (2009)
Cannabidiol in Medicine: A Review of its Therapeutic Potential in CNS Disorders
Caterina Scuderi et al.
PHYTOTHERAPY RESEARCH (2009)
Accumulation of 15-deoxy-Δ12,14-prostaglandin J2 adduct formation with Keap1 over time:: effects on potency for intracellular antioxidant defence induction
Joo Yeun Oh et al.
BIOCHEMICAL JOURNAL (2008)
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Delta(9)-tetrahydrocannabinol, cannabidiol and Delta(9)-tetrahydrocannabivarin
R. G. Pertwee
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2
Jingbo Pi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Time-dependent behavioral recovery after sepsis in rats
Lisiane Tuon et al.
INTENSIVE CARE MEDICINE (2008)
Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor
Gregory I. Liou et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
G. Esposito et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
Jacqueline L. Blankman et al.
CHEMISTRY & BIOLOGY (2007)
Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors
Onintza Sagredo et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Detecting oxidative post-translational modifications in proteins
E. Gianazza et al.
AMINO ACIDS (2007)
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease:: Importance of antioxidant and cannabinoid receptor-independent properties
Moises Garcia-Arencibia et al.
BRAIN RESEARCH (2007)
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
Barbara Costa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells
P. Massi et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in β-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-κB involvement
Giuseppe Esposito et al.
NEUROSCIENCE LETTERS (2006)
The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway rescue in PC12 cells
G Esposito et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Cannabinoid receptors regulate Ca2+ signals and insulin secretion in pancreatic β-cell
P Juan-Picó et al.
CELL CALCIUM (2006)
Peripheral cannabinoid receptor, CB2, regulates bone mass
O Ofek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes
AB El-Remessy et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
E Russo et al.
MEDICAL HYPOTHESES (2006)
Oxidative stress and neurodegeneration: where are we now?
Barry Halliwell
JOURNAL OF NEUROCHEMISTRY (2006)
Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
C Hamelink et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Endocannabinoid signaling in rat somatosensory cortex:: Laminar differences and involvement of specific interneuron types
AL Bodor et al.
JOURNAL OF NEUROSCIENCE (2005)
Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro:: Relevance to Parkinson's disease
I Lastres-Becker et al.
NEUROBIOLOGY OF DISEASE (2005)
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription
MJ Calkins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on β-amyloid-induced toxicity in PC12 cells
T Iuvone et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw
B Costa et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Brain β-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1
BJ Turner et al.
NEUROCHEMICAL RESEARCH (2004)
Inducible nitric oxide synthase and argininosuccinate synthetase:: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with β-amyloid 1-42 in vitro
J Haas et al.
NEUROSCIENCE LETTERS (2002)
Evidence of oxidative damage in Alzheimer's disease brain:: central role for amyloid β-peptide
DA Butterfield et al.
TRENDS IN MOLECULAR MEDICINE (2001)
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
BF Cravatt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)