Related references
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Review
Medicine, General & Internal
Mayumi Matsuda et al.
Summary: COVID-19 vaccines have been distributed to prevent and mitigate COVID-19 since December 2020. However, there is limited information on the long-term safety of these vaccines. This report presents three cases of adult-onset Still's disease (AOSD) that occurred after COVID-19 vaccination, along with a literature review. The cases included moderate to severe AOSD, with two cases complicated by macrophage activation syndrome. Glucocorticoid therapy, immunosuppressive drugs, and biologic agents were effective in treating all 17 cases of new-onset or relapsed AOSD following COVID-19 vaccination.
Article
Rheumatology
Shu-Yi Koh et al.
Summary: This is the first case report of newly diagnosed seronegative peripheral SpA in an autoimmunity-disease-free individual following mRNA BNT coronavirus disease 2019 vaccination. Treatment with etanercept resulted in significant improvement of symptoms.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2023)
Review
Rheumatology
Shivraj Padiyar et al.
Summary: We report three cases of AOSD-like presentations following vaccination with the ChAdOx1 nCoV-19 vaccine in previously healthy females. These cases highlight the immunogenicity of COVID-19 vaccines and the potential occurrence of new-onset systemic hyper-inflammation illness, ranging in severity from mild to life-threatening.
CLINICAL RHEUMATOLOGY
(2022)
Review
Rheumatology
Ji-Won Kim et al.
Summary: This study reports a case of a 49-year-old female who experienced a flare of adult-onset Still's disease (AOSD) after receiving the first dose of BNT162b2 mRNA COVID-19 vaccination. The patient presented with fever and nausea 4 days after vaccination and was ultimately treated with steroid pulse therapy. The study also discusses possible mechanisms linking vaccination with a flare of AOSD.
CLINICAL RHEUMATOLOGY
(2022)
Review
Surgery
Avinash Mani et al.
Summary: Thromboembolic events can occur after COVID-19 vaccination, most commonly after the AstraZeneca vaccine. Cerebral sinus thrombosis is the most common manifestation noted in vaccinated individuals.
ANNALS OF VASCULAR SURGERY
(2022)
Letter
Virology
Rohit Singh et al.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Rheumatology
Lisa G. Rider et al.
Summary: The study found that disease flares requiring changes in treatment after COVID-19 vaccination were uncommon among patients with systemic rheumatic diseases. Certain SRD types like systemic lupus erythematosus, psoriatic arthritis, and polymyalgia rheumatica were associated with higher odds of flare, while idiopathic inflammatory myopathies were associated with lower odds. The Oxford-AstraZeneca vaccine, a prior reaction to a non-COVID-19 vaccine, and female sex were identified as potential risk factors for disease flares following vaccination.
Letter
Rheumatology
Ludwig Knabl et al.
Article
Immunology
Tomohiro Watanabe et al.
Summary: COVID-19 vaccination may induce autoimmune responses, leading to the development of autoimmune diseases. This article reports a case of new-onset rheumatoid arthritis (RA) following COVID-19 vaccination, and the study found that the production of cytokines IL-6, TNF-α, and type I IFN may be involved in this new-onset RA.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Haruka Yonezawa et al.
Summary: Although COVID-19 mRNA vaccines have been effective in reducing the severity of the disease, some patients may experience severe adverse reactions and newly onset autoimmune phenomena, such as rheumatoid arthritis. This report presents a case of new-onset seropositive rheumatoid arthritis following COVID-19 mRNA vaccination.
Article
Medicine, General & Internal
Hiroshi Shimagami et al.
Summary: Exacerbation of rheumatic disease has been reported after SARS-CoV-2 vaccination, although there are few cases of new-onset rheumatic diseases. We present two cases of new-onset persistent polyarthritis following mRNA vaccination against SARS-CoV-2. One patient developed bilateral pleural effusions with significantly elevated serum interferon (IFN)-beta levels, while the other patient had no effusion and serum IFN-beta levels comparable to healthy individuals. Treatment with 20 mg prednisolone was effective for both patients. Although further investigations are needed, the marked increase in serum IFN-beta levels observed in the patient with pleural effusion may suggest an excessive response from the innate immune system to mRNA vaccines.
Article
Rheumatology
Eliska Vanaskova et al.
Summary: This article reports a rare case of synovitis in the knee joint after the first dose of mRNA vaccine. Through comprehensive examination and treatment, the patient eventually made a full recovery.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2022)
Review
Immunology
Poramed Winichakoon et al.
Summary: This study reported a rare case of Adult-onset Still's disease (AOSD)-like syndrome as a complication of COVID-19 vaccination. A total of 11 cases, including the one in this report, developed AOSD-like syndrome after vaccination, with fever and joint pain being the main clinical findings. Treatment with non-steroidal anti-inflammatory drugs and high-dose corticosteroids showed good responses.
Article
Medicine, General & Internal
Carson Flores et al.
Summary: Shoulder injury related to vaccine administration (SIRVA) is a recognized complication caused by incorrectly administered intramuscular deltoid vaccinations. This case report illustrates a patient with shoulder pain and focal osseous edema in the humeral head due to suboptimal needle placement, leading to the diagnosis of SIRVA.
Article
Medicine, General & Internal
Nicolas Roux et al.
Summary: A woman in her 30s developed unilateral acute sacroiliitis after receiving the COVID-19 vaccine. The pelvic scan revealed inflammatory joint edges, bone erosion, and a mass in the muscle. The patient didn't show any signs of infection or inflammation, suggesting that this could be a reaction to the vaccine.
Article
Immunology
Xiang-He Chua et al.
Summary: This article reports a case of a 30-year-old woman who developed symptoms of general weakness, sore throat, skin rashes, arthralgia, and persistent fever after receiving the Moderna COVID-19 vaccine. The patient was diagnosed with adult-onset Still's disease (AOSD), and the study suggests a potential association between COVID-19 vaccination and immunogenicity and inflammatory responses.
Article
Surgery
Prapakorn Klabklay et al.
Summary: This is a case report of a patient who developed septic arthritis of the shoulder after receiving the Astra-Zeneca COVID-19 vaccine. The patient, a 45-year-old Thai female, presented with left shoulder pain, limited range of motion, and fever. The possible risk factors were underlying type II diabetes mellitus and vaccine administration technique. The joint fluid culture showed Staphylococcus aureus. The patient was treated with combined arthroscopic debridement and intravenous antibiotics for 1 week, followed by oral antibiotics for 5 weeks. Her clinical symptoms gradually improved over the 2 weeks following the initiation of treatment.
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS
(2022)
Article
Medicine, General & Internal
Sebastian E. Ibanez Vodnizza et al.
Summary: A woman in her 60s with a history of adult-onset Still's disease received the ChAdOx1-S vaccine as a booster and experienced reactivation of AOSD. Treatment with tocilizumab resulted in complete remission of symptoms and normalization of laboratory tests.
Letter
Rheumatology
Arvind Nune et al.
INDIAN JOURNAL OF RHEUMATOLOGY
(2022)
Letter
Immunology
Amir Sharabi et al.
CLINICAL IMMUNOLOGY
(2021)
Letter
Medicine, General & Internal
Aoife Sweeney et al.
INTERNAL MEDICINE JOURNAL
(2021)
Article
Immunology
Ayse Unal Enginar
Summary: While most COVID-19 patients have mild symptoms, a small percentage may develop severe pneumonia or even arthritis. Some patients may experience joint pain or arthritis after receiving the COVID-19 vaccine.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Letter
Rheumatology
Chokan Baimukhamedov et al.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2021)
Editorial Material
Rheumatology
Flavia Leone et al.
LANCET RHEUMATOLOGY
(2021)
Letter
Rheumatology
Chokan Baimukhamedov
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
Qi-jun An et al.
Summary: Reactive arthritis (ReA) following COVID-19 vaccination is rare but the benefits of vaccination outweigh potential risks. Future attention should focus on identifying individuals at higher risk for developing autoimmune diseases after COVID-19 vaccination and exploring more versatile and safer vaccines.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Review
Immunology
Konstantinos Katsikas Triantafyllidis et al.
Summary: After receiving COVID-19 vaccines, some individuals may experience reactivation of varicella zoster virus (VZV) leading to herpes zoster (HZ), with hypertension and autoimmune conditions such as rheumatoid arthritis being common comorbidities. Treatment with oral valacyclovir is commonly used, and increased awareness and early recognition of this condition are crucial for optimal management.
Article
Medicine, General & Internal
Seong Yeon Park et al.
Summary: A case of adult-onset Still's disease (AOSD) developing in a 36-year-old woman after receiving the first dose of the Pfizer COVID-19 vaccine is reported. The patient experienced high fever and sore throat, leading to the diagnosis of AOSD and treatment with steroids and tocilizumab. This report suggests a potential link between COVID-19 vaccines and the triggering of AOSD through activation of the innate immune system.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Hakjun Hyun et al.
Summary: Several unusual cases of polyarthralgia and myalgia syndrome were reported in South Korea after receiving the AstraZeneca vaccine, with patients having a median age of 67 years. Symptoms lasted for up to 47 days and were relieved with medication treatment. Further monitoring is needed to understand the long-term prognosis of this syndrome.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Robert Costigan Flowers et al.
Summary: A 68-year-old female presented with left shoulder pain, decreased ROM, and fever following COVID-19 vaccination. Investigations revealed septic arthritis due to Streptococcus gordonii. Proper vaccination technique should be followed to avoid complications. Symptoms such as pain, fever, and decreased ROM following vaccination should raise suspicion for septic arthritis.
Editorial Material
Virology
Hongzhou Lu et al.
JOURNAL OF MEDICAL VIROLOGY
(2020)
Review
Rheumatology
Edward M. Behrens et al.
ARTHRITIS & RHEUMATOLOGY
(2017)
Editorial Material
Public, Environmental & Occupational Health
Andreas Stang
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2010)