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Snail and Slug Promote Epithelial-Mesenchymal Transition through β-Catenin-T-Cell Factor-4-dependent Expression of Transforming Growth Factor-β3
Damian Medici et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
p53: The Janus of autophagy?
Beth Levine et al.
NATURE CELL BIOLOGY (2008)
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions
Vera V. Teplova et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2007)
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance
Jennifer S. Carew et al.
BLOOD (2007)
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation
Anna Colell et al.
CELL (2007)
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
Ravi K. Amaravadi et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Autophagy delays apoptotic death in breast cancer cells following DNA damage
M. J. Abedin et al.
CELL DEATH AND DIFFERENTIATION (2007)
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
Shida Yousefi et al.
NATURE CELL BIOLOGY (2006)
Rapamycin pre-treatment protects against apoptosis
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2006)
Adding chloroquine to conventional treatment for glioblastoma multiforme -: A randomized, double-blind, placebo-controlled trial
J Sotelo et al.
ANNALS OF INTERNAL MEDICINE (2006)
Kinesin-2 is a motor for late endosomes and lysosomes
CL Brown et al.
TRAFFIC (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Differential lysosomal proteolysis in antigen-presenting CeRs determines antigen fate
L Delamarre et al.
SCIENCE (2005)
Inhibition of macroautophagy triggers apoptosis
P Boya et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
T Kanzawa et al.
CELL DEATH AND DIFFERENTIATION (2004)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
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